Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 103 | 2019 |
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle A Diaz-Vegas, S Madsen, KC Cooke, L Carroll, JXY Khor, N Turner, ... Elife 12, RP87340, 2023 | 25 | 2023 |
Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... American Journal of Respiratory Cell and Molecular Biology 67 (1), 99-111, 2022 | 14 | 2022 |
Protein dynamics underlying allosteric regulation MA Astore, AS Pradhan, EH Thiede, SM Hanson Current Opinion in Structural Biology 84, 102768, 2024 | 13 | 2024 |
Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... Iscience 25 (1), 2022 | 9 | 2022 |
S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy in vivo and in vitro in matched pediatric patient-derived cell models KM Allan, MA Astore, LK Fawcett, SL Wong, PC Chen, R Griffith, A Jaffe, ... Frontiers in Pediatrics 10, 1062766, 2022 | 5 | 2022 |
CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM M Jeon, R Raghu, M Astore, G Woollard, R Feathers, A Kaz, SM Hanson, ... arXiv preprint arXiv:2408.05526, 2024 | 4 | 2024 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt, Nat. Commun. 10 (2019) 5486 Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... | 4 | |
Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a … KM Allan, MA Astore, E Kardia, SL Wong, LK Fawcett, JL Bell, S Visser, ... Frontiers in Molecular Biosciences 10, 1148501, 2023 | 1 | 2023 |
Tracking Policy Implications and Impacts of the COVID-19 Pandemic and Related Executive Actions on a Sampling of Foreign-born Early Career Researchers in the US C Jorgensen, MA Astore, F Sancheznieto, S Vedachalam, A Mughal, ... OSF, 2022 | 1 | 2022 |
Probing heterogeneity of TRPV1: A comparison of state-of-the-art methods in cryo-EM MA Astore, R Blackwell, P Cossio, SM Hanson Biophysical Journal 123 (3), 134a, 2024 | | 2024 |
Heterogeneity in ligand-bound TRPV1: A comparison of methods in cryo-EM and molecular dynamics simulation MA Astore, R Blackwell, D Silva-Sanchez, PM Cossio, SM Hanson bioRxiv, 2024.10. 07.617120, 2024 | | 2024 |
Computer modelling the root cause of cystic fibrosis MA Astore, PC Chen, S Waters, S Kuyucak Biophysical Journal 121 (3), 506a, 2022 | | 2022 |
In silico and functional characterisation of an ultra-rare CFTR mutation identifies novel lasso motif interactions regulating channel gating SL Wong, NT Awatade, MA Astore, KM Allan, MJ Carnell, I Slapetova, ... bioRxiv, 2021.12. 12.472297, 2021 | | 2021 |
Molecular Dynamics to Explain the Pathogenesis of Gating Class Cystic Fibrosis Mutations MA Astore, PC Chen, S Waters, S Kuyucak Biophysical Journal 120 (3), 247a, 2021 | | 2021 |
FUNCTIONAL AND PHARMACOLOGICAL CHARACTERIZATION OF RARE R352Q CFTR MUTATION IN PATIENT-DERIVED DIFFERENTIATED NASAL EPITHELIAL CELLS AND INTESTINAL ORGANOIDS S Wong, N Awatade, K Allan, M Astore, M Carnell, E Pandzic, L Fawcett, ... RESPIROLOGY 25, 55-55, 2020 | | 2020 |
CryoBench: Datasets and Benchmarks for Heterogeneous Cryo-EM Reconstruction M Jeon, R Raghu, MA Astore, G Woollard, JR Feathers, A Kaz, ... The Thirty-eight Conference on Neural Information Processing Systems …, 0 | | |