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Hui-Ju Tseng
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Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach
KC Hsu, CY Liu, TE Lin, JH Hsieh, TY Sung, HJ Tseng, JM Yang, ...
Scientific Reports 7 (1), 3228, 2017
512017
Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease
HJ Tseng, MH Lin, YJ Shiao, YC Yang, JC Chu, CY Chen, YY Chen, ...
European Journal of Medicinal Chemistry 192, 112193, 2020
432020
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for …
HJ Tseng, S Banerjee, B Qian, MJ Lai, TY Wu, TI Hsu, TE Lin, KC Hsu, ...
European Journal of Medicinal Chemistry 256, 115459, 2023
342023
Biological evaluation of selected flavonoids as inhibitors of MNKs targeting acute myeloid leukemia
LC Chen, HL Huang, WC HuangFu, SC Yen, ST Ngo, YW Wu, TE Lin, ...
Journal of Natural Products 83 (10), 2967-2975, 2020
232020
Investigation of selected flavonoid derivatives as potent FLT3 inhibitors for the potential treatment of acute myeloid leukemia
SC Yen, LC Chen, HL Huang, ST Ngo, YW Wu, TE Lin, TY Sung, ST Lien, ...
Journal of Natural Products 84 (1), 1-10, 2021
172021
Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors
KC Hsu, JC Chu, HJ Tseng, CI Liu, HC Wang, TE Lin, HS Lee, LW Hsin, ...
European Journal of Medicinal Chemistry 219, 113419, 2021
132021
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative
LC Chen, KC Hsu, LC Chiou, HJ Tseng, WJ Huang
Molecules 22 (11), 1897, 2017
132017
Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach
SC Yen, LC Chen, HL Huang, WC HuangFu, YY Chen, TE Lin, ST Lien, ...
Bioorganic Chemistry 121, 105675, 2022
122022
Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation
LC Chen, HJ Tseng, CY Liu, YY Huang, CC Yen, JR Weng, YL Lu, ...
Frontiers in Pharmacology 9, 708, 2018
82018
O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia
SC Yen, YW Wu, CC Huang, MW Chao, HJ Tu, LC Chen, TE Lin, TY Sung, ...
Phytomedicine 100, 154061, 2022
72022
Synthesis of Yakuchinone B-inspired inhibitors against islet amyloid polypeptide aggregation
JY Hsu, A Rao Sathyan, KC Hsu, LC Chen, CC Yen, HJ Tseng, KC Wu, ...
Journal of Natural Products 84 (4), 1096-1103, 2021
52021
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
JY Hsu, KC Hsu, C Sun, CH Chou, TE Lin, TY Sung, HJ Tseng, SC Yen, ...
Biomedicine & Pharmacotherapy 159, 114258, 2023
42023
Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities
JC Chu, HJ Tseng, SB Lee, KC Hsu, LW Hsin, RH Liang, TE Lin, NC Gao, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2212326, 2023
12023
Method for preparing hispidulin and its derivatives
WJ Huang, KC Hsu, LC Chiou, LC Chen, HJ Tseng, PC Fan
US Patent 10,532,991, 2020
2020
Discovery of novel class IIa-selective histone deacetylase inhibitors using an in silico virtual screening approach
HJ Tseng, CY Liu, CY Chen, KC Hsu, WJ Huang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Synthesis of Yakuchinone-derived compounds that inhibit beta-amyloid aggregation
LC Chen, CC Yen, HJ Tseng, YY Huang, YL Lu, WC Hou, KC Hsu, I Pan, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
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