Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach KC Hsu, CY Liu, TE Lin, JH Hsieh, TY Sung, HJ Tseng, JM Yang, ... Scientific Reports 7 (1), 3228, 2017 | 51 | 2017 |
Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease HJ Tseng, MH Lin, YJ Shiao, YC Yang, JC Chu, CY Chen, YY Chen, ... European Journal of Medicinal Chemistry 192, 112193, 2020 | 43 | 2020 |
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for … HJ Tseng, S Banerjee, B Qian, MJ Lai, TY Wu, TI Hsu, TE Lin, KC Hsu, ... European Journal of Medicinal Chemistry 256, 115459, 2023 | 34 | 2023 |
Biological evaluation of selected flavonoids as inhibitors of MNKs targeting acute myeloid leukemia LC Chen, HL Huang, WC HuangFu, SC Yen, ST Ngo, YW Wu, TE Lin, ... Journal of Natural Products 83 (10), 2967-2975, 2020 | 23 | 2020 |
Investigation of selected flavonoid derivatives as potent FLT3 inhibitors for the potential treatment of acute myeloid leukemia SC Yen, LC Chen, HL Huang, ST Ngo, YW Wu, TE Lin, TY Sung, ST Lien, ... Journal of Natural Products 84 (1), 1-10, 2021 | 17 | 2021 |
Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors KC Hsu, JC Chu, HJ Tseng, CI Liu, HC Wang, TE Lin, HS Lee, LW Hsin, ... European Journal of Medicinal Chemistry 219, 113419, 2021 | 13 | 2021 |
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative LC Chen, KC Hsu, LC Chiou, HJ Tseng, WJ Huang Molecules 22 (11), 1897, 2017 | 13 | 2017 |
Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach SC Yen, LC Chen, HL Huang, WC HuangFu, YY Chen, TE Lin, ST Lien, ... Bioorganic Chemistry 121, 105675, 2022 | 12 | 2022 |
Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation LC Chen, HJ Tseng, CY Liu, YY Huang, CC Yen, JR Weng, YL Lu, ... Frontiers in Pharmacology 9, 708, 2018 | 8 | 2018 |
O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia SC Yen, YW Wu, CC Huang, MW Chao, HJ Tu, LC Chen, TE Lin, TY Sung, ... Phytomedicine 100, 154061, 2022 | 7 | 2022 |
Synthesis of Yakuchinone B-inspired inhibitors against islet amyloid polypeptide aggregation JY Hsu, A Rao Sathyan, KC Hsu, LC Chen, CC Yen, HJ Tseng, KC Wu, ... Journal of Natural Products 84 (4), 1096-1103, 2021 | 5 | 2021 |
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors JY Hsu, KC Hsu, C Sun, CH Chou, TE Lin, TY Sung, HJ Tseng, SC Yen, ... Biomedicine & Pharmacotherapy 159, 114258, 2023 | 4 | 2023 |
Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities JC Chu, HJ Tseng, SB Lee, KC Hsu, LW Hsin, RH Liang, TE Lin, NC Gao, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2212326, 2023 | 1 | 2023 |
Method for preparing hispidulin and its derivatives WJ Huang, KC Hsu, LC Chiou, LC Chen, HJ Tseng, PC Fan US Patent 10,532,991, 2020 | | 2020 |
Discovery of novel class IIa-selective histone deacetylase inhibitors using an in silico virtual screening approach HJ Tseng, CY Liu, CY Chen, KC Hsu, WJ Huang ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Synthesis of Yakuchinone-derived compounds that inhibit beta-amyloid aggregation LC Chen, CC Yen, HJ Tseng, YY Huang, YL Lu, WC Hou, KC Hsu, I Pan, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |