Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ... Nature communications 8 (1), 15132, 2017 | 283 | 2017 |
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ... Nature communications 9 (1), 347, 2018 | 199 | 2018 |
Configurable user-interface component management system O Dando US Patent 6,944,829, 2005 | 190 | 2005 |
Amyloid beta and tau cooperate to cause reversible behavioral and transcriptional deficits in a model of Alzheimer’s disease EK Pickett, AG Herrmann, J McQueen, K Abt, O Dando, J Tulloch, P Jain, ... Cell reports 29 (11), 3592-3604. e5, 2019 | 150 | 2019 |
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley, D Hampton, M Torvell, ... Nature communications 13 (1), 135, 2022 | 112 | 2022 |
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis AR Mehta, JM Gregory, O Dando, RN Carter, K Burr, J Nanda, D Story, ... Acta neuropathologica 141, 257-279, 2021 | 102 | 2021 |
Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology C Zhao, AC Devlin, AK Chouhan, BT Selvaraj, M Stavrou, K Burr, V Brivio, ... Glia 68 (5), 1046-1064, 2020 | 101 | 2020 |
Cell-type-specific translation profiling reveals a novel strategy for treating fragile X syndrome SR Thomson, SS Seo, SA Barnes, SR Louros, M Muscas, O Dando, ... Neuron 95 (3), 550-563. e5, 2017 | 95 | 2017 |
Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes PS Baxter, O Dando, K Emelianova, X He, S McKay, GE Hardingham, ... Cell reports 34 (12), 2021 | 78 | 2021 |
Characterisation of CDKL5 Transcript Isoforms in Human and Mouse RD Hector, O Dando, N Landsberger, C Kilstrup-Nielsen, PC Kind, ... PloS one 11 (6), e0157758, 2016 | 73 | 2016 |
Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome A Asiminas, AD Jackson, SR Louros, SM Till, T Spano, O Dando, MF Bear, ... Science translational medicine 11 (494), eaao0498, 2019 | 67 | 2019 |
Altered dendritic spine function and integration in a mouse model of fragile X syndrome SA Booker, APF Domanski, OR Dando, AD Jackson, JTR Isaac, ... Nature communications 10 (1), 4813, 2019 | 50 | 2019 |
Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction EM Perkins, K Burr, P Banerjee, AR Mehta, O Dando, BT Selvaraj, ... Molecular neurodegeneration 16, 1-16, 2021 | 44 | 2021 |
Input-output relationship of CA1 pyramidal neurons reveals intact homeostatic mechanisms in a mouse model of fragile X syndrome SA Booker, LS De Oliveira, NJ Anstey, Z Kozic, OR Dando, AD Jackson, ... Cell Reports 32 (6), 2020 | 44 | 2020 |
Reversal of proliferation deficits caused by chromosome 16p13. 11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor … M Johnstone, NA Vasistha, MC Barbu, O Dando, K Burr, E Christopher, ... Molecular psychiatry 24 (2), 294-311, 2019 | 40 | 2019 |
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons J Qiu, J McQueen, B Bilican, O Dando, D Magnani, K Punovuori, ... Elife 5, e20337, 2016 | 36 | 2016 |
Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells P Banerjee, E Paza, EM Perkins, OG James, B Kenkhuis, AF Lloyd, K Burr, ... Stem Cell Research 49, 102046, 2020 | 35 | 2020 |
Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription J Qiu, O Dando, PS Baxter, P Hasel, S Heron, TI Simpson, ... Nature Protocols 13 (10), 2176-2199, 2018 | 33 | 2018 |
Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling NM Markus, P Hasel, J Qiu, KFS Bell, S Heron, PC Kind, O Dando, ... PloS one 11 (2), e0148164, 2016 | 33 | 2016 |
Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress BR Al-Mubarak, KFS Bell, S Chowdhry, PJ Meakin, PS Baxter, S McKay, ... Redox biology 47, 102158, 2021 | 20 | 2021 |