| Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function L Belloni, T Pollicino, F De Nicola, F Guerrieri, G Raffa, M Fanciulli, ... Proceedings of the National Academy of Sciences 106 (47), 19975-19979, 2009 | 557 | 2009 |
| Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas E Botti, G Spallone, F Moretti, B Marinari, V Pinetti, S Galanti, ... Proceedings of the National Academy of Sciences 108 (33), 13710-13715, 2011 | 166 | 2011 |
| KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden D Marinelli, M Mazzotta, S Scalera, I Terrenato, F Sperati, L D'Ambrosio, ... Annals of Oncology 31 (12), 1746-1754, 2020 | 163 | 2020 |
| Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint T Bruno, F De Nicola, S Iezzi, D Lecis, C D'Angelo, M Di Padova, N Corbi, ... Cancer cell 10 (6), 473-486, 2006 | 147 | 2006 |
| Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb T Bruno, R De Angelis, F De Nicola, C Barbato, M Di Padova, N Corbi, ... Cancer cell 2 (5), 387-399, 2002 | 96 | 2002 |
| CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells G Manic, M Signore, A Sistigu, G Russo, F Corradi, S Siteni, M Musella, ... Gut 67 (5), 903-917, 2018 | 89 | 2018 |
| Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy A Desantis, T Bruno, V Catena, F De Nicola, F Goeman, S Iezzi, C Sorino, ... The EMBO Journal 34 (9), 1214-1230, 2015 | 76 | 2015 |
| NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death MG Di Certo, N Corbi, T Bruno, S Iezzi, F De Nicola, A Desantis, MT Ciotti, ... Journal of cell science 120 (11), 1852-1858, 2007 | 73 | 2007 |
| Mutations in the KEAP1-NFE2L2 pathway define a molecular subset of rapidly progressing lung adenocarcinoma F Goeman, F De Nicola, S Scalera, F Sperati, E Gallo, L Ciuffreda, ... Journal of Thoracic Oncology 14 (11), 1924-1934, 2019 | 71 | 2019 |
| Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation T Bruno, A Desantis, G Bossi, S Di Agostino, C Sorino, F De Nicola, ... Cancer cell 18 (2), 122-134, 2010 | 64 | 2010 |
| Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter M Di Padova, T Bruno, F De Nicola, S Iezzi, C D'Angelo, R Gallo, ... Journal of Biological Chemistry 278 (38), 36496-36504, 2003 | 63 | 2003 |
| Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B M Musella, A Guarracino, N Manduca, C Galassi, E Ruggiero, A Potenza, ... Nature immunology 23 (9), 1379-1392, 2022 | 57 | 2022 |
| The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage F De Nicola, T Bruno, S Iezzi, M Di Padova, A Floridi, C Passananti, ... Journal of Biological Chemistry 282 (27), 19685-19691, 2007 | 53 | 2007 |
| VDR primary targets by genome-wide transcriptional profiling F Goeman, F De Nicola, PDO De Meo, M Pallocca, B Elmi, T Castrignanò, ... The Journal of steroid biochemistry and molecular biology 143, 348-356, 2014 | 50 | 2014 |
| Che-1 activates XIAP expression in response to DNA damage T Bruno, S Iezzi, F De Nicola, M Di Padova, A Desantis, M Scarsella, ... Cell Death & Differentiation 15 (3), 515-520, 2008 | 46 | 2008 |
| Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53 A Desantis, T Bruno, V Catena, F De Nicola, F Goeman, S Iezzi, C Sorino, ... Cell death & disease 6 (5), e1764-e1764, 2015 | 41 | 2015 |
| Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth L Aurisicchio, E Salvatori, L Lione, S Bandini, M Pallocca, R Maggio, ... Journal of Experimental & Clinical Cancer Research 38, 1-13, 2019 | 39 | 2019 |
| KEAP1 and TP53 frame genomic, evolutionary, and immunologic subtypes of lung adenocarcinoma with different sensitivity to immunotherapy S Scalera, M Mazzotta, G Corleone, F Sperati, I Terrenato, E Krasniqi, ... Journal of Thoracic Oncology 16 (12), 2065-2077, 2021 | 35 | 2021 |
| DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first‐line chemotherapy L Ronchetti, E Melucci, F De Nicola, F Goeman, B Casini, F Sperati, ... International Journal of Cancer 140 (11), 2587-2595, 2017 | 35 | 2017 |
| Conditionally reprogrammed cells (CRC) methodology does not allow the in vitro expansion of patient‐derived primary and metastatic lung cancer cells G Sette, V Salvati, I Giordani, E Pilozzi, D Quacquarini, E Duranti, ... International journal of cancer 143 (1), 88-99, 2018 | 29 | 2018 |
