Variable prediction accuracy of polygenic scores within an ancestry group H Mostafavi*, A Harpak*, I Agarwal, D Conley, JK Pritchard, M Przeworski eLife 9, e48376, 2020 | 368 | 2020 |
Reduced signal for polygenic adaptation of height in UK Biobank JJ Berg*, A Harpak*, N Sinnott-Armstrong*, AM Joergensen, H Mostafavi, ... eLife 8, e39725, 2019 | 363 | 2019 |
Between-region genetic divergence reflects the mode and tempo of tumor evolution R Sun, Z Hu, A Sottoriva, TA Graham, A Harpak, Z Ma, JM Fischer, ... Nature genetics 49 (7), 1015-1024, 2017 | 171 | 2017 |
Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling A Raj, SH Wang, H Shim, A Harpak, YI Li, B Engelmann, M Stephens, ... eLife 5, e13328, 2016 | 146 | 2016 |
Mutation rate variation is a primary determinant of the distribution of allele frequencies in humans A Harpak*, A Bhaskar*, JK Pritchard PLoS Genetics 12 (12), 2016 | 90 | 2016 |
Evidence for weak selective constraint on human gene expression EC Glassberg*, Z Gao*, A Harpak, X Lan, JK Pritchard Genetics 211 (2), 757-772, 2019 | 55 | 2019 |
The evolution of group differences in changing environments A Harpak, M Przeworski PLoS Biology 19 (1), e3001072, 2021 | 44 | 2021 |
Amplification is the primary mode of gene-by-sex interaction in complex human traits C Zhu, MJ Ming, JM Cole, M Kirkpatrick, MD Edge, A Harpak Cell Genomics 3 (5), 2023 | 41 | 2023 |
Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates A Harpak*, X Lan*, Z Gao, JK Pritchard Proceedings of the National Academy of Sciences 114 (48), 12779-12784, 2017 | 39 | 2017 |
Concerted evolution reveals co-adapted amino acid substitutions in Na+ K+-ATPase of frogs that prey on toxic toads S Mohammadi*, L Yang*, A Harpak*, S Herrera-Álvarez, ... Current Biology, 2021 | 28 | 2021 |
Genetic adaptation in New York city rats A Harpak, N Garud, NA Rosenberg, DA Petrov, M Combs, PS Pennings, ... Genome Biology and Evolution 13 (1), evaa247, 2021 | 23 | 2021 |
1,000 ancient genomes uncover 10,000 years of natural selection in Europe MK Le, OS Smith, A Akbari, A Harpak, D Reich, VM Narasimhan bioRxiv, 2023 | 12 | 2023 |
Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium V Garcia, EC Glassberg, A Harpak, MW Feldman Journal of The Royal Society Interface 15 (140), 20170921, 2018 | 10 | 2018 |
Calibrated prediction intervals for polygenic scores across diverse contexts K Hou, Z Xu, Y Ding, R Mandla, Z Shi, K Boulier, A Harpak, B Pasaniuc Nature Genetics, 1-11, 2024 | 6 | 2024 |
Mutability of demographic noise in microbial range expansions QQ Yu, M Gralka, MC Duvernoy, M Sousa, A Harpak, O Hallatschek The ISME journal 15 (9), 2643-2654, 2021 | 6 | 2021 |
Accounting for statistical non-additive interactions enables the recovery of missing heritability from GWAS summary statistics SP Smith, G Darnell, D Udwin, A Harpak, S Ramachandran, L Crawford bioRxiv, 2022.07. 21.501001, 2022 | 5* | 2022 |
GWAS deems parents guilty by association A Harpak, MD Edge Proceedings of the National Academy of Sciences 118 (27), e2109433118, 2021 | 3 | 2021 |
Neutral Null Models For Diversity In Serial Transfer Evolution Experiments A Harpak, G Sella Evolution 68 (9), 2727-2736, 2014 | 3 | 2014 |
Tradeoffs in Modeling Context Dependency in Complex Trait Genetics E Weine, SP Smith, RK Knowlton, A Harpak bioRxiv, 2023.06. 21.545998, 2023 | 1 | 2023 |
Does standard adjustment for genomic population structure capture direct genetic effects? R Sotoudeh, S Trejo, A Harpak, D Conley bioRxiv, 2024.05. 03.592431, 2024 | | 2024 |