关注
Chen Li
Chen Li
在 bidmc.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
C Yan, L Gong, L Chen, M Xu, H Abou-Hamdan, M Tang, L Désaubry, ...
Autophagy 16 (3), 419-434, 2020
3132020
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development
Z Wu, M Zuo, L Zeng, K Cui, B Liu, C Yan, L Chen, J Dong, F Shangguan, ...
EMBO reports 22 (1), e50827, 2021
1072021
Sam50 regulates PINK1-Parkin-mediated mitophagy by controlling PINK1 stability and mitochondrial morphology
F Jian, D Chen, L Chen, C Yan, B Lu, Y Zhu, S Chen, A Shi, DC Chan, ...
Cell reports 23 (10), 2989-3005, 2018
992018
Sam50–Mic19–Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact
J Tang, K Zhang, J Dong, C Yan, C Hu, H Ji, L Chen, S Chen, H Zhao, ...
Cell Death & Differentiation 27 (1), 146-160, 2020
932020
Loss of Sam50 in hepatocytes induces cardiolipin‐dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury
L Chen, J Dong, S Liao, S Wang, Z Wu, M Zuo, B Liu, C Yan, Y Chen, ...
Hepatology 76 (5), 1389-1408, 2022
652022
The fate of damaged mitochondrial DNA in the cell
S Liao, L Chen, Z Song, H He
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (5), 119233, 2022
502022
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis
Y Chen, Z Wu, S Huang, X Wang, S He, L Liu, Y Hu, L Chen, P Chen, ...
Nature metabolism 4 (9), 1166-1184, 2022
332022
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease
J Dong, L Chen, F Ye, J Tang, B Liu, J Lin, PH Zhou, B Lu, M Wu, JH Lu, ...
Nature Communications 15 (1), 168, 2024
152024
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1
Z Wang, D Zhang, X Qiu, H Inuzuka, Y Xiong, J Liu, L Chen, H Chen, ...
Journal of the American Chemical Society 146 (11), 7584-7593, 2024
72024
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice
F Dang, L Bai, J Dong, X Hu, J Wang, JA Paulo, Y Xiong, X Liang, Y Sun, ...
Science Translational Medicine 15 (725), eadh7668, 2023
62023
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK
J Liu, X Hu, K Luo, Y Xiong, L Chen, Z Wang, H Inuzuka, C Qian, X Yu, ...
Journal of the American Chemical Society 146 (16), 11507-11514, 2024
32024
Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2
Z Wang, J Liu, X Qiu, D Zhang, H Inuzuka, L Chen, H Chen, L Xie, ...
Journal of the American Chemical Society 145 (40), 21871-21878, 2023
22023
The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS
Z Deng, L Chen, C Qian, J Liu, Q Wu, X Song, Y Xiong, Z Wang, X Hu, ...
Angewandte Chemie International Edition, e202415168, 0
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