Dual-function nanosystem for synergetic cancer chemo-/radiotherapy through ROS-mediated signaling pathways L He, H Lai, T Chen Biomaterials 51, 30-42, 2015 | 137 | 2015 |
Rational design and action mechanisms of chemically innovative organoselenium in cancer therapy Z Chen, H Lai, L Hou, T Chen Chemical Communications 56 (2), 179-196, 2020 | 129 | 2020 |
RGD peptide-conjugated selenium nanoparticles: antiangiogenesis by suppressing VEGF-VEGFR2-ERK/AKT pathway X Fu, Y Yang, X Li, H Lai, Y Huang, L He, W Zheng, T Chen Nanomedicine: Nanotechnology, Biology and Medicine 12 (6), 1627-1639, 2016 | 128 | 2016 |
Functionalization and cancer-targeting design of ruthenium complexes for precise cancer therapy J Liu, H Lai, Z Xiong, B Chen, T Chen Chemical Communications 55 (67), 9904-9914, 2019 | 120 | 2019 |
Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase Z Luo, L Yu, F Yang, Z Zhao, B Yu, H Lai, KH Wong, SM Ngai, W Zheng, ... Metallomics 6 (8), 1480-1490, 2014 | 105 | 2014 |
Boosting natural killer cell-based cancer immunotherapy with selenocystine/transforming growth factor-beta inhibitor-encapsulated nanoemulsion C Liu, H Lai, T Chen ACS nano 14 (9), 11067-11082, 2020 | 78 | 2020 |
Selenium-containing ruthenium complex synergizes with natural killer cells to enhance immunotherapy against prostate cancer via activating TRAIL/FasL signaling H Lai, D Zeng, C Liu, Q Zhang, X Wang, T Chen Biomaterials 219, 119377, 2019 | 65 | 2019 |
Antiangiogenic ruthenium(ii) benzimidazole complexes, structure-based activation of distinct signaling pathways H Lai, Z Zhao, L Li, W Zheng, T Chen Metallomics 7 (3), 439-447, 2015 | 65 | 2015 |
Selenadiazole derivatives as theranostic agents for simultaneous cancer chemo-/radiotherapy by targeting thioredoxin reductase L He, S Ji, H Lai, T Chen Journal of Materials Chemistry B 3 (42), 8383-8393, 2015 | 54 | 2015 |
Biomedical application of reactive oxygen species–responsive nanocarriers in cancer, inflammation, and neurodegenerative diseases J Liu, Y Li, S Chen, Y Lin, H Lai, B Chen, T Chen Frontiers in Chemistry 8, 838, 2020 | 41 | 2020 |
A Universally EDTA-assisted synthesis of polytypic bismuth telluride nanoplates with a size-dependent enhancement of tumor radiosensitivity and metabolism in vivo Z Song, T Liu, H Lai, X Meng, L Yang, J Su, T Chen ACS nano 16 (3), 4379-4396, 2022 | 22 | 2022 |
Facile synthesis of antioxidative nanotherapeutics using a microwave for efficient reversal of cisplatin-induced nephrotoxicity H Lai, X Zhang, Z Song, Z Yuan, L He, T Chen Chemical Engineering Journal 391, 123563, 2020 | 22 | 2020 |
Selenadiazole Derivatives Inhibit Angiogenesis‐Mediated Human Breast Tumor Growth by Suppressing the VEGFR2‐Mediated ERK and AKT Signaling Pathways H Lai, X Fu, C Sang, L Hou, P Feng, X Li, T Chen Chemistry–An Asian Journal 13 (11), 1447-1457, 2018 | 21 | 2018 |
Selenium substitution endows cystine with radiosensitization activity against cervical cancer cells Q Xie, L He, H Lai, W Zheng, T Chen RSC advances 4 (64), 34210-34216, 2014 | 21 | 2014 |
Enhancement of antiangiogenic efficacy of iron (II) complex by selenium substitution H Lai, X Zhang, P Feng, L Xie, J Chen, T Chen Chemistry–An Asian Journal 12 (9), 982-987, 2017 | 19 | 2017 |
Iron (II)− Polypyridyl Complexes Inhibit the Growth of Glioblastoma Tumor and Enhance TRAIL‐Induced Cell Apoptosis H Lin, Y Wang, H Lai, X Li, T Chen Chemistry–An Asian Journal 13 (18), 2730-2738, 2018 | 17 | 2018 |
TRPM8-regulated calcium mobilization plays a critical role in synergistic chemosensitization of Borneol on Doxorubicin H Lai, C Liu, L Hou, W Lin, T Chen, A Hong Theranostics 10 (22), 10154, 2020 | 14 | 2020 |
Thermosensitive selenium hydrogel boosts antitumor immune response for hepatocellular carcinoma chemoradiotherapy C Liu, R Lin, H Lai, F Pi, Q Xue, T Chen, W He Nano Today 50, 101823, 2023 | 12 | 2023 |
Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine H Lai, L Xu, C Liu, S Shi, Y Jiang, Y Yu, B Deng, T Chen Signal Transduction and Targeted Therapy 8 (1), 88, 2023 | 11 | 2023 |
Selenadiazole derivatives antagonize glucocorticoid-induced osteoblasts cells apoptosis by blocking ROS-mediated signaling, a new anti-osteoporosis strategy Y Du, H Li, B Chen, H Lai, X Li, T Chen RSC advances 7 (47), 29656-29664, 2017 | 6 | 2017 |