Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance MS Braza, MMT van Leent, M Lameijer, BL Sanchez-Gaytan, RJW Arts, ... Immunity 49 (5), 819-828. e6, 2018 | 205 | 2018 |
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ... Nature biomedical engineering 2 (5), 279-292, 2018 | 115 | 2018 |
Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183 (3), 786-801. e19, 2020 | 114 | 2020 |
Immune checkpoint inhibitor therapy aggravates T cell–driven plaque inflammation in atherosclerosis K Poels, MMT van Leent, C Boutros, H Tissot, S Roy, AE Meerwaldt, ... Cardio Oncology 2 (4), 599-610, 2020 | 90 | 2020 |
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... ACS nano 14 (7), 7832-7846, 2020 | 78 | 2020 |
High-density lipoprotein nanobiologics for precision medicine WJM Mulder, MMT Van Leent, M Lameijer, EA Fisher, ZA Fayad, ... Accounts of chemical research 51 (1), 127-137, 2018 | 71 | 2018 |
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species T Binderup, R Duivenvoorden, F Fay, MMT van Leent, J Malkus, S Baxter, ... Science translational medicine 11 (506), eaaw7736, 2019 | 64 | 2019 |
Regulating trained immunity with nanomedicine MMT van Leent, B Priem, DP Schrijver, A de Dreu, SRJ Hofstraat, ... Nature Reviews Materials 7 (6), 465-481, 2022 | 61 | 2022 |
Antibody-mediated inhibition of CTLA4 aggravates atherosclerotic plaque inflammation and progression in hyperlipidemic mice K Poels, MMT van Leent, ME Reiche, PJH Kusters, S Huveneers, ... Cells 9 (9), 1987, 2020 | 53 | 2020 |
Prosaposin mediates inflammation in atherosclerosis MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ... Science translational medicine 13 (584), eabe1433, 2021 | 52 | 2021 |
Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging ML Senders, AE Meerwaldt, MMT van Leent, BL Sanchez-Gaytan, ... Nature nanotechnology 15 (5), 398-405, 2020 | 52 | 2020 |
Nanoimmunotherapy to treat ischaemic heart disease R Duivenvoorden, ML Senders, MMT van Leent, C Pérez-Medina, ... Nature Reviews Cardiology 16 (1), 21-32, 2019 | 52 | 2019 |
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs M Nahrendorf, FF Hoyer, AE Meerwaldt, MMT van Leent, ML Senders, ... Circulation: Cardiovascular Imaging 13 (10), e010586, 2020 | 39 | 2020 |
Hydroxychloroquine inhibits the trained innate immune response to interferons N Rother, C Yanginlar, RGH Lindeboom, S Bekkering, MMT van Leent, ... Cell Reports Medicine 1 (9), 2020 | 34 | 2020 |
A modular approach toward producing nanotherapeutics targeting the innate immune system MMT van Leent, AE Meerwaldt, A Berchouchi, YC Toner, ME Burnett, ... Science advances 7 (10), eabe7853, 2021 | 24 | 2021 |
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation YC Toner, AA Ghotbi, S Naidu, K Sakurai, MMT van Leent, S Jordan, ... Scientific reports 12 (1), 6185, 2022 | 20 | 2022 |
FSH-blocking therapeutic for osteoporosis S Gera, TC Kuo, AA Gumerova, F Korkmaz, D Sant, V DeMambro, ... Elife 11, e78022, 2022 | 15 | 2022 |
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells DP Schrijver, RJ Röring, J Deckers, A de Dreu, YC Toner, G Prevot, ... Nature Biomedical Engineering 7 (9), 1097-1112, 2023 | 11 | 2023 |
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis P Panizzi, M Krohn-Grimberghe, E Keliher, YX Ye, J Grune, ... Science translational medicine 12 (568), eaay2104, 2020 | 8 | 2020 |
Multiparametric immunoimaging maps inflammatory signatures in murine myocardial infarction models A Maier, YC Toner, J Munitz, NAT Sullivan, K Sakurai, AE Meerwaldt, ... Basic to Translational Science 8 (7), 801-816, 2023 | 7 | 2023 |