FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons J Gilley, PJ Coffer, J Ham The Journal of cell biology 162 (4), 613-622, 2003 | 832 | 2003 |
Wallerian degeneration: an emerging axon death pathway linking injury and disease L Conforti, J Gilley, MP Coleman Nature Reviews Neuroscience 15 (6), 394-409, 2014 | 627 | 2014 |
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons J Gilley, MP Coleman PLoS biology 8 (1), e1000300, 2010 | 527 | 2010 |
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ... Science 365 (6455), 793-799, 2019 | 408 | 2019 |
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, ... Cell Death & Differentiation 22 (5), 731-742, 2015 | 261 | 2015 |
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons J Gilley, G Orsomando, I Nascimento-Ferreira, MP Coleman Cell reports 10 (12), 1974-1981, 2015 | 194 | 2015 |
Rescue of peripheral and CNS axon defects in mice lacking NMNAT2 J Gilley, R Adalbert, G Yu, MP Coleman Journal of Neuroscience 33 (33), 13410-13424, 2013 | 139 | 2013 |
Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo E Babetto, B Beirowski, L Janeckova, R Brown, J Gilley, D Thomson, ... Journal of Neuroscience 30 (40), 13291-13304, 2010 | 137 | 2010 |
WldS protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice L Conforti, A Wilbrey, G Morreale, L Janeckova, B Beirowski, R Adalbert, ... Journal of Cell Biology 184 (4), 491-500, 2009 | 131 | 2009 |
Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2 S Milde, J Gilley, MP Coleman PLoS biology 11 (4), e1001539, 2013 | 127 | 2013 |
Non-nuclear WldS determines its neuroprotective efficacy for axons and synapses in vivo B Beirowski, E Babetto, J Gilley, F Mazzola, L Conforti, L Janeckova, ... Journal of Neuroscience 29 (3), 653-668, 2009 | 119 | 2009 |
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ... Neurobiology of disease 134, 104678, 2020 | 114 | 2020 |
Sarm1 deletion, but not WldS, confers lifelong rescue in a mouse model of severe axonopathy J Gilley, RR Ribchester, MP Coleman Cell reports 21 (1), 10-16, 2017 | 113 | 2017 |
NMN deamidase delays Wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo M Di Stefano, A Loreto, G Orsomando, V Mori, F Zamporlini, RP Hulse, ... Current Biology 27 (6), 784-794, 2017 | 104 | 2017 |
Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a “P301L” tau knockin mouse J Gilley, A Seereeram, K Ando, S Mosely, S Andrews, M Kerschensteiner, ... Neurobiology of aging 33 (3), 621. e1-621. e15, 2012 | 100 | 2012 |
Aβ, tau and ApoE4 in Alzheimer's disease: the axonal connection R Adalbert, J Gilley, MP Coleman Trends in molecular medicine 13 (4), 135-142, 2007 | 94 | 2007 |
Difference Tracker: ImageJ plugins for fully automated analysis of multiple axonal transport parameters S Andrews, J Gilley, MP Coleman Journal of neuroscience methods 193 (2), 281-287, 2010 | 92 | 2010 |
Nicotinamide Mononucleotide Adenylyltransferase 2 (Nmnat2) Regulates Axon Integrity in the Mouse Embryo AN Hicks, D Lorenzetti, J Gilley, B Lu, KE Andersson, C Miligan, ... Public Library of Science 7 (10), e47869, 2012 | 89 | 2012 |
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons T Rodríguez-Martín, AM Pooler, DHW Lau, GM Mórotz, KJ De Vos, ... Neurobiology of disease 85, 1-10, 2016 | 72 | 2016 |
SARM1 is a multi-functional NAD (P) ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites C Angeletti, A Amici, J Gilley, A Loreto, AG Trapanotto, C Antoniou, ... Iscience 25 (2), 103812, 2022 | 60 | 2022 |