Search for nucleation sites in smaller fragments of chymotrypsin inhibitor 2 LS Itzhaki, JL Neira, J Ruiz-Sanz, G de Prat Gay, AR Fersht Journal of molecular biology 254 (2), 289-304, 1995 | 87 | 1995 |
Conformational pathway of the polypeptide chain of chymotrypsin inhibitor-2 growing from its N terminusin vitro. Parallels with the protein folding pathway G de Prat Gay, J Ruiz-Sanz, JL Neira, FJ Corrales, DE Otzen, ... Journal of molecular biology 254 (5), 968-979, 1995 | 77 | 1995 |
The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase AM Lambeir, J Backmann, J Ruiz‐Sanz, V Filimonov, JE Nielsen, ... European Journal of Biochemistry 267 (9), 2516-2524, 2000 | 72 | 2000 |
Folding of a nascent polypeptide chain in vitro: cooperative formation of structure in a protein module. G de Prat Gay, J Ruiz-Sanz, JL Neira, LS Itzhaki, AR Fersht Proceedings of the National Academy of Sciences 92 (9), 3683-3686, 1995 | 72 | 1995 |
New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells B Alburquerque-González, M Bernabé-García, S Montoro-García, ... Experimental & Molecular Medicine 52 (2), 281-292, 2020 | 53 | 2020 |
Protein fragments as models for events in protein folding pathways: protein engineering analysis of the association of two complementary fragments of the barley chymotrypsin … J Ruiz-Sanz, G de Gay, DE Otzen, AR Fersht Biochemistry 34 (5), 1695-1701, 1995 | 53 | 1995 |
The structure of the transition state for the association of two fragments of the barley chymotrypsin inhibitor 2 to generate native-like protein: implications for mechanisms … G de Prat Gay, J Ruiz-Sanz, B Davis, AR Fersht Proceedings of the National Academy of Sciences 91 (23), 10943-10946, 1994 | 49 | 1994 |
A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains ES Cobos, MT Pisabarro, MC Vega, E Lacroix, L Serrano, J Ruiz-Sanz, ... Journal of molecular biology 342 (1), 355-365, 2004 | 44 | 2004 |
Isothermal titration calorimetry: thermodynamic analysis of the binding thermograms of molecular recognition events by using equilibrium models JC Martinez, J Murciano-Calles, ES Cobos, M Iglesias-Bexiga, I Luque, ... Applications of calorimetry in a wide context—differential scanning …, 2013 | 41 | 2013 |
Two-state dynamics of the SH3–SH2 tandem of Abl kinase and the allosteric role of the N-cap C Corbi-Verge, F Marinelli, A Zafra-Ruano, J Ruiz-Sanz, I Luque, ... Proceedings of the National Academy of Sciences 110 (36), E3372-E3380, 2013 | 38 | 2013 |
The influence of effectors and subunit interactions on Escherichia coli carbamoyl-phosphate synthetase studied by differential scanning calorimetry J Cervera, F Conejero-Lara, J Ruiz-Sanz, ML Galisteo, PL Mateo, ... Journal of Biological Chemistry 268 (17), 12504-12511, 1993 | 35 | 1993 |
The FDA-approved antiviral raltegravir inhibits fascin1-dependent invasion of colorectal tumor cells in vitro and in vivo B Alburquerque-González, Á Bernabé-García, M Bernabé-García, ... Cancers 13 (4), 861, 2021 | 34 | 2021 |
Generation of a family of protein fragments for structure-folding studies. 2. Kinetics of association of the two chymotrypsin inhibitor-2 fragments G Prat Gay, J Ruiz-Sanz, AR Fersht Biochemistry 33 (25), 7964-7970, 1994 | 33 | 1994 |
Thermodynamic analysis of the unfolding and stability of the dimeric DNA‐binding protein HU from the hyperthermophilic eubacterium Thermotoga maritima and its … J Ruiz‐Sanz, VV Filimonov, E Christodoulou, CE Vorgias, PL Mateo European journal of biochemistry 271 (8), 1497-1507, 2004 | 32 | 2004 |
Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition JM Martin-Garcia, J Ruiz-Sanz, I Luque Biochemical Journal 442 (2), 443-451, 2012 | 31 | 2012 |
The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein JM Martin-Garcia, I Luque, J Ruiz-Sanz, A Camara-Artigas Acta Crystallographica Section D: Biological Crystallography 68 (8), 1030-1040, 2012 | 27 | 2012 |
Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation JM Martín-García, I Luque, PL Mateo, J Ruiz-Sanz, A Cámara-Artigas FEBS letters 581 (9), 1701-1706, 2007 | 27 | 2007 |
Thermodynamic characterization of the folding equilibrium of the human Nedd4-WW4 domain: at the frontiers of cooperative folding ES Cobos, M Iglesias-Bexiga, J Ruiz-Sanz, PL Mateo, I Luque, ... Biochemistry 48 (36), 8712-8720, 2009 | 25 | 2009 |
Thermodynamic analysis of the structural stability of phage 434 Cro protein S Padmanabhan, DV Laurents, AM Fernandez, M Elias-Arnanz, ... Biochemistry 38 (47), 15536-15547, 1999 | 25 | 1999 |
Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding A Cámara-Artigas, JM Martín-García, B Morel, J Ruiz-Sanz, I Luque FEBS letters 583 (4), 749-753, 2009 | 24 | 2009 |