Functional selectivity and classical concepts of quantitative pharmacology JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007 | 1314 | 2007 |
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus KA Berg, S Maayani, J Goldfarb, C Scaramellini, P Leff, WP Clarke Molecular pharmacology 54 (1), 94-104, 1998 | 611 | 1998 |
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens P De Deurwaerdère, S Navailles, KA Berg, WP Clarke, U Spampinato Journal of Neuroscience 24 (13), 3235-3241, 2004 | 382 | 2004 |
RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity KA Berg, JD Cropper, CM Niswender, E Sanders‐Bush, RB Emeson, ... British journal of pharmacology 134 (2), 386-392, 2001 | 177 | 2001 |
Bradykinin-induced functional competence and trafficking of the δ-opioid receptor in trigeminal nociceptors AM Patwardhan, KA Berg, AN Akopain, NA Jeske, N Gamper, WP Clarke, ... Journal of Neuroscience 25 (39), 8825-8832, 2005 | 175 | 2005 |
Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems. KA Berg, WP Clarke, C Sailstad, A Saltzman, S Maayani Molecular pharmacology 46 (3), 477-484, 1994 | 166 | 1994 |
Making sense of pharmacology: inverse agonism and functional selectivity KA Berg, WP Clarke International Journal of Neuropsychopharmacology 21 (10), 962-977, 2018 | 152 | 2018 |
Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors KA Berg, JA Harvey, U Spampinato, WP Clarke Trends in pharmacological sciences 26 (12), 625-630, 2005 | 152 | 2005 |
Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors VJ Aloyo, KA Berg, U Spampinato, WP Clarke, JA Harvey Pharmacology & therapeutics 121 (2), 160-173, 2009 | 134 | 2009 |
Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats. WP Clarke, FD Yocca, S Maayani Journal of Pharmacology and Experimental Therapeutics 277 (3), 1259-1266, 1996 | 134 | 1996 |
The elusive nature of intrinsic efficacy WP Clarke, RA Bond Trends in pharmacological sciences 19 (7), 270-276, 1998 | 133 | 1998 |
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT) 2A and 5-HT2C receptors PR Moya, KA Berg, MA Gutierrez-Hernandez, P Saez-Briones, ... Journal of Pharmacology and Experimental Therapeutics 321 (3), 1054-1061, 2007 | 131 | 2007 |
Novel actions of inverse agonists on 5-HT2C receptor systems KA Berg, BD Stout, JD Cropper, S Maayani, WP Clarke Molecular pharmacology 55 (5), 863-872, 1999 | 122 | 1999 |
Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications KA Berg, WP Clarke, KA Cunningham, U Spampinato Neuropharmacology 55 (6), 969-976, 2008 | 114 | 2008 |
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter ME Gnegy, H Khoshbouei, KA Berg, JA Javitch, WP Clarke, M Zhang, ... Molecular pharmacology 66 (1), 137-143, 2004 | 110 | 2004 |
Conflicting responses: the experiences of fathers of infants diagnosed with severe congenital heart disease SM Clark, MS Miles Journal for Specialists in Pediatric Nursing 4 (1), 7-14, 1999 | 110 | 1999 |
Physiological and therapeutic relevance of constitutive activity of 5-HT2A and 5-HT2C receptors for the treatment of depression KA Berg, JA Harvey, U Spampinato, WP Clarke Progress in brain research 172, 287-305, 2008 | 103 | 2008 |
Pleiotropic Behavior of 5‐HT2A and 5‐HT2C Receptor Agonists KA Berg, WP Clarke, S Maayani, J Goldfarb Annals of the New York Academy of Sciences 861 (1), 104-110, 1998 | 97 | 1998 |
Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation KA Berg, BD Stout, S Maayani, WP Clarke Journal of Pharmacology and Experimental Therapeutics 299 (2), 593-602, 2001 | 90 | 2001 |
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms. KA Berg, WP Clarke, Y Chen, BJ Ebersole, RD McKay, S Maayani Molecular Pharmacology 45 (5), 826-836, 1994 | 89 | 1994 |