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William P Clarke
William P Clarke
Professor of Pharmacology, University of Texas Health Science Center
在 uthscsa.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
13142007
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus
KA Berg, S Maayani, J Goldfarb, C Scaramellini, P Leff, WP Clarke
Molecular pharmacology 54 (1), 94-104, 1998
6111998
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens
P De Deurwaerdère, S Navailles, KA Berg, WP Clarke, U Spampinato
Journal of Neuroscience 24 (13), 3235-3241, 2004
3822004
RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity
KA Berg, JD Cropper, CM Niswender, E Sanders‐Bush, RB Emeson, ...
British journal of pharmacology 134 (2), 386-392, 2001
1772001
Bradykinin-induced functional competence and trafficking of the δ-opioid receptor in trigeminal nociceptors
AM Patwardhan, KA Berg, AN Akopain, NA Jeske, N Gamper, WP Clarke, ...
Journal of Neuroscience 25 (39), 8825-8832, 2005
1752005
Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems.
KA Berg, WP Clarke, C Sailstad, A Saltzman, S Maayani
Molecular pharmacology 46 (3), 477-484, 1994
1661994
Making sense of pharmacology: inverse agonism and functional selectivity
KA Berg, WP Clarke
International Journal of Neuropsychopharmacology 21 (10), 962-977, 2018
1522018
Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors
KA Berg, JA Harvey, U Spampinato, WP Clarke
Trends in pharmacological sciences 26 (12), 625-630, 2005
1522005
Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors
VJ Aloyo, KA Berg, U Spampinato, WP Clarke, JA Harvey
Pharmacology & therapeutics 121 (2), 160-173, 2009
1342009
Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats.
WP Clarke, FD Yocca, S Maayani
Journal of Pharmacology and Experimental Therapeutics 277 (3), 1259-1266, 1996
1341996
The elusive nature of intrinsic efficacy
WP Clarke, RA Bond
Trends in pharmacological sciences 19 (7), 270-276, 1998
1331998
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT) 2A and 5-HT2C receptors
PR Moya, KA Berg, MA Gutierrez-Hernandez, P Saez-Briones, ...
Journal of Pharmacology and Experimental Therapeutics 321 (3), 1054-1061, 2007
1312007
Novel actions of inverse agonists on 5-HT2C receptor systems
KA Berg, BD Stout, JD Cropper, S Maayani, WP Clarke
Molecular pharmacology 55 (5), 863-872, 1999
1221999
Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications
KA Berg, WP Clarke, KA Cunningham, U Spampinato
Neuropharmacology 55 (6), 969-976, 2008
1142008
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter
ME Gnegy, H Khoshbouei, KA Berg, JA Javitch, WP Clarke, M Zhang, ...
Molecular pharmacology 66 (1), 137-143, 2004
1102004
Conflicting responses: the experiences of fathers of infants diagnosed with severe congenital heart disease
SM Clark, MS Miles
Journal for Specialists in Pediatric Nursing 4 (1), 7-14, 1999
1101999
Physiological and therapeutic relevance of constitutive activity of 5-HT2A and 5-HT2C receptors for the treatment of depression
KA Berg, JA Harvey, U Spampinato, WP Clarke
Progress in brain research 172, 287-305, 2008
1032008
Pleiotropic Behavior of 5‐HT2A and 5‐HT2C Receptor Agonists
KA Berg, WP Clarke, S Maayani, J Goldfarb
Annals of the New York Academy of Sciences 861 (1), 104-110, 1998
971998
Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation
KA Berg, BD Stout, S Maayani, WP Clarke
Journal of Pharmacology and Experimental Therapeutics 299 (2), 593-602, 2001
902001
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms.
KA Berg, WP Clarke, Y Chen, BJ Ebersole, RD McKay, S Maayani
Molecular Pharmacology 45 (5), 826-836, 1994
891994
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