Profiling of discrete gynecological cancers reveals novel transcriptional modules and common features shared by other cancer types and embryonic stem cells KI Pappa, A Polyzos, J Jacob-Hirsch, N Amariglio, GD Vlachos, ... PloS one 10 (11), e0142229, 2015 | 393 | 2015 |
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 287 | 2016 |
A new tumor suppressor role for the Notch pathway in bladder cancer T Rampias, P Vgenopoulou, M Avgeris, A Polyzos, K Stravodimos, ... Nature medicine 20 (10), 1199-1205, 2014 | 199 | 2014 |
A deep learning framework for predicting response to therapy in cancer T Sakellaropoulos, K Vougas, S Narang, F Koinis, A Kotsinas, A Polyzos, ... Cell reports 29 (11), 3367-3373. e4, 2019 | 180 | 2019 |
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks DC Di Giammartino, A Kloetgen, A Polyzos, Y Liu, D Kim, D Murphy, ... Nature cell biology 21 (10), 1179-1190, 2019 | 136 | 2019 |
The lysine‐specific methyltransferase KMT 2C/MLL 3 regulates DNA repair components in cancer T Rampias, D Karagiannis, M Avgeris, A Polyzos, A Kokkalis, Z Kanaki, ... EMBO reports 20 (3), e46821, 2019 | 130 | 2019 |
IFNα impairs autophagic degradation of mtDNA promoting autoreactivity of SLE monocytes in a STING-dependent fashion K Gkirtzimanaki, E Kabrani, D Nikoleri, A Polyzos, A Blanas, ... Cell reports 25 (4), 921-933. e5, 2018 | 109 | 2018 |
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining K Vougas, T Sakellaropoulos, A Kotsinas, GRP Foukas, A Ntargaras, ... Pharmacology & therapeutics 203, 107395, 2019 | 106 | 2019 |
Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells T Alissafi, A Hatzioannou, K Mintzas, RM Barouni, A Banos, S Sormendi, ... The Journal of clinical investigation 128 (9), 3840-3852, 2018 | 94 | 2018 |
Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer D Stellas, M Szabolcs, S Koul, Z Li, A Polyzos, C Anagnostopoulos, ... Journal of the National Cancer Institute 106 (12), dju320, 2014 | 91 | 2014 |
RbAp48 protein is a critical component of GPR158/OCN signaling and ameliorates age-related memory loss S Kosmidis, A Polyzos, L Harvey, M Youssef, CA Denny, A Dranovsky, ... Cell reports 25 (4), 959-973. e6, 2018 | 74 | 2018 |
Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer E Papadimitriou, E Pantazaka, P Castana, T Tsalios, A Polyzos, D Beis Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866 (2), 252-265, 2016 | 69 | 2016 |
Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements A Antonaki, C Demetriades, A Polyzos, A Banos, G Vatsellas, MD Lavigne, ... Journal of Biological Chemistry 286 (44), 38768-38782, 2011 | 67 | 2011 |
H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization B Pelham-Webb, A Polyzos, L Wojenski, A Kloetgen, J Li, ... Molecular cell 81 (8), 1732-1748. e8, 2021 | 66 | 2021 |
Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability P Galanos, G Pappas, A Polyzos, A Kotsinas, I Svolaki, NN Giakoumakis, ... Genome biology 19, 1-18, 2018 | 63 | 2018 |
Transcription factors: building hubs in the 3D space DC Di Giammartino, A Polyzos, E Apostolou Cell Cycle 19 (19), 2395-2410, 2020 | 51 | 2020 |
A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced … ES Komseli, IS Pateras, T Krejsgaard, K Stawiski, SV Rizou, A Polyzos, ... BMC genomics 19, 1-22, 2018 | 51 | 2018 |
Composite macroH2A/NRF-1 nucleosomes suppress noise and generate robustness in gene expression MD Lavigne, G Vatsellas, A Polyzos, E Mantouvalou, G Sianidis, ... Cell reports 11 (7), 1090-1101, 2015 | 47 | 2015 |
A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization CP Zampetidis, P Galanos, A Angelopoulou, Y Zhu, A Polyzou, ... Molecular Cell 81 (23), 4907-4923. e8, 2021 | 41 | 2021 |
Inflammatory bowel disease in children: the role of a positive family history ES Roma, J Panayiotou, J Pachoula, C Constantinidou, A Polyzos, ... European journal of gastroenterology & hepatology 22 (6), 710-715, 2010 | 41 | 2010 |