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Victor Lau
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An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease
V Lau, L Ramer, MÈ Tremblay
Nature Communications 14 (1), 1670, 2023
922023
Going Too Far Is the Same as Falling Short: Kinesin-3 Family Members in Hereditary Spastic Paraplegia
DR Gabrych, VZ Lau, S Niwa, MA Silverman
Frontiers in Cellular Neuroscience 13, 419, 2019
602019
Investigating microglial ultrastructural alterations and intimate relationships with neuronal stress, dystrophy, and degeneration in mouse models of Alzheimer’s disease
MK St-Pierre, M Carrier, V Lau, MÈ Tremblay
Neuronal Cell Death: Methods and Protocols, 29-58, 2022
132022
È (2023) An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease. Nat Commun 14: 1670
V Lau, L Ramer, M Tremblay
5
The inflammation-induced dysregulation of reelin homeostasis hypothesis of Alzheimer’s disease
BS Reive, V Lau, CL Sánchez-Lafuente, A Henri-Bhargava, LE Kalynchuk, ...
Journal of Alzheimer’s Disease 100 (4), 1099-1119, 2024
22024
Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2
HA Vecchiarelli, K Bisht, KP Sharma, S Weiser Novak, ME Traetta, ...
bioRxiv, 2024.10. 15.618087, 2024
12024
Chronic stress induces senescence build-up early in life
V Lau, I Awogbindin, MÈ Tremblay
Nature Aging, 1-3, 2025
2025
Exploring iron deposition patterns using light and electron microscopy in the mouse brain across aging and Alzheimer’s disease pathology conditions
V Lau, J VanderZwaag, C Murray, MÈ Tremblay
2024
Light and electron microscopy reveal iron deposition patterns and novel iron-rich cell states across aging and Alzheimer’s disease pathology conditions
V Lau
2024
The Glial Aging & Senescence Hypothesis of Late-onset Alzheimer’s
V Lau, L Ramer, MÈ Tremblay
Preprints, 2022
2022
How Senescent Glia Drive And Underlie Alzheimer’s Disease: A Predictive Model
VZ Lau, L Ramer, MÈ Tremblay
Preprints, 2021
2021
Alzheimer’s: Aging and Dysfunctional Glia? Giving a “DAM”!
V Lau
SFU Undergraduate Research Symposium Journal 2, 2021
2021
A Unified Framework of Alzheimer's Disease: Prioritizing & Targeting Dysfunctional Microglia
V Lau
SFU Undergraduate Research Symposium Journal 1 (1), 2020
2020
Going Too Far Is the Same as Falling Short
DR Gabrych, VZ Lau, S Niwa, MA Silverman
Frontiers in cellular neuroscience 13, 2019
2019
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