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Phospholipase Cγ1 is required for metastasis development and progression G Sala, F Dituri, C Raimondi, S Previdi, T Maffucci, M Mazzoletti, C Rossi, ... Cancer research 68 (24), 10187-10196, 2008 | 178 | 2008 |
The G‐protein‐coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1 M Sallese, L Salvatore, E D'Urbano, G Sala, M Storto, T Launey, ... The FASEB Journal 14 (15), 2569-2580, 2000 | 158 | 2000 |
Feedback inhibition by RALT controls signal output by the ErbB network S Anastasi, L Fiorentino, M Fiorini, R Fraioli, G Sala, L Castellani, S Alema, ... Oncogene 22 (27), 4221-4234, 2003 | 145 | 2003 |
Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin S Anastasi, G Sala, C Huiping, E Caprini, G Russo, S Iacovelli, F Lucini, ... Oncogene 24 (28), 4540-4548, 2005 | 140 | 2005 |
Antibody-drug conjugates: the new frontier of chemotherapy S Ponziani, G Di Vittorio, G Pitari, AM Cimini, M Ardini, R Gentile, ... International Journal of Molecular Sciences 21 (15), 5510, 2020 | 120 | 2020 |
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine R Ferro, A Adamska, R Lattanzio, I Mavrommati, CE Edling, SA Arifin, ... Oncogene 37 (49), 6368-6382, 2018 | 107 | 2018 |
miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance A De Cola, S Volpe, MC Budani, M Ferracin, R Lattanzio, A Turdo, ... Cell death & disease 6 (7), e1823-e1823, 2015 | 94 | 2015 |
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages A Rosati, A Basile, R D’Auria, M d’Avenia, M De Marco, A Falco, M Festa, ... Nature communications 6 (1), 8695, 2015 | 91 | 2015 |
Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control M Fiorini, C Ballaro, G Sala, G Falcone, S Alema, O Segatto Oncogene 21 (42), 6530-6539, 2002 | 89 | 2002 |
Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer G Corda, G Sala, R Lattanzio, M Iezzi, M Sallese, G Fragassi, ... The Journal of pathology 241 (3), 350-361, 2017 | 80 | 2017 |
Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target E Capone, S Iacobelli, G Sala Journal of translational medicine 19 (1), 405, 2021 | 77 | 2021 |
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines M Momeny, JM Saunus, F Marturana, AEMC Reed, D Black, G Sala, ... Oncotarget 6 (6), 3932, 2015 | 74 | 2015 |
Role of BAG3 in cancer progression: A therapeutic opportunity M De Marco, A Basile, V Iorio, M Festa, A Falco, B Ranieri, M Pascale, ... Seminars in cell & developmental biology 78, 85-92, 2018 | 64 | 2018 |
Negative regulation of receptor tyrosine kinase signals M Fiorini, M Alimandi, L Fiorentino, G Sala, O Segatto FEBS letters 490 (3), 132-141, 2001 | 62 | 2001 |
A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation T Maffucci, C Raimondi, S Abu-Hayyeh, V Dominguez, G Sala, I Zachary, ... PloS one 4 (12), e8285, 2009 | 55 | 2009 |
Therapeutic efficacy of the novel stimuli-sensitive nano-ferritins containing doxorubicin in a head and neck cancer model V Damiani, E Falvo, G Fracasso, L Federici, M Pitea, V De Laurenzi, ... International journal of molecular sciences 18 (7), 1555, 2017 | 43 | 2017 |
ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) PR Prasetyanti, E Capone, D Barcaroli, D D'Agostino, S Volpe, ... Oncotarget 6 (19), 16902, 2015 | 39 | 2015 |
Secreted Gal-3BP is a novel promising target for non-internalizing Antibody–Drug Conjugates F Giansanti, E Capone, S Ponziani, E Piccolo, R Gentile, A Lamolinara, ... Journal of Controlled Release 294, 176-184, 2019 | 38 | 2019 |
Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8+ T cell number and tumour growth in pancreatic cancer V Iorio, A Rosati, R D’Auria, M De Marco, L Marzullo, A Basile, M Festa, ... Gut 67 (4), 780-782, 2018 | 36 | 2018 |