The regulation and functions of DNA and RNA G-quadruplexes D Varshney, J Spiegel, K Zyner, D Tannahill, S Balasubramanian Nature reviews Molecular cell biology 21 (8), 459-474, 2020 | 844 | 2020 |
The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues S Al-Mahdawi, RM Pinto, O Ismail, D Varshney, S Lymperi, C Sandi, ... Human molecular genetics 17 (5), 735-746, 2008 | 318 | 2008 |
GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology S Al-Mahdawi, RM Pinto, D Varshney, L Lawrence, MB Lowrie, S Hughes, ... Genomics 88 (5), 580-590, 2006 | 271 | 2006 |
Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts B Herdy, C Mayer, D Varshney, G Marsico, P Murat, C Taylor, C D'Santos, ... Nucleic Acids Research 46 (21), 11592-11604, 2018 | 119 | 2018 |
SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation D Varshney, J Vavrova-Anderson, AJ Oler, VH Cowling, BR Cairns, ... Nature communications 6 (1), 6569, 2015 | 99 | 2015 |
Promoter G-quadruplex folding precedes transcription and is controlled by chromatin J Shen, D Varshney, A Simeone, X Zhang, S Adhikari, D Tannahill, ... Genome biology 22 (1), 143, 2021 | 74 | 2021 |
Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM D Varshney, AP Petit, JA Bueren-Calabuig, C Jansen, DA Fletcher, ... Nucleic acids research 44 (21), 10423-10436, 2016 | 66 | 2016 |
CDK1-cyclin B1 activates RNMT, coordinating mRNA cap methylation with G1 phase transcription M Aregger, A Kaskar, D Varshney, ME Fernandez-Sanchez, ... Molecular cell 61 (5), 734-746, 2016 | 48 | 2016 |
mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II-dependent transcription D Varshney, O Lombardi, G Schweikert, S Dunn, O Suska, VH Cowling Cell reports 23 (5), 1530-1542, 2018 | 42 | 2018 |
AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11 D Piscitello, D Varshney, S Lilla, MG Vizioli, C Reid, V Gorbunova, ... Oncogene 37 (4), 427-438, 2018 | 42 | 2018 |
DNA G-quadruplex recognition in vitro and in live cells by a structure-specific nanobody S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, ... Journal of the American Chemical Society 144 (50), 23096-23103, 2022 | 29 | 2022 |
RNA G-quadruplex structures control ribosomal protein production D Varshney, SM Cuesta, B Herdy, UB Abdullah, D Tannahill, ... Scientific Reports 11 (1), 22735, 2021 | 29 | 2021 |
RNA isolation and quantitative PCR from HOPE-and formalin-fixed bovine lymph node tissues J Witchell, D Varshney, T Gajjar, A Wangoo, M Goyal Pathology-Research and Practice 204 (2), 105-111, 2008 | 23 | 2008 |
c-Myc deregulation induces mRNA capping enzyme dependency O Lombardi, D Varshney, NM Phillips, VH Cowling Oncotarget 7 (50), 82273, 2016 | 20 | 2016 |
Selective repression of SINE transcription by RNA polymerase III D Varshney, J Vavrova-Anderson, AJ Oler, BR Cairns, RJ White Mobile genetic elements 5 (6), 86-91, 2015 | 8 | 2015 |
Regulation of RNA polymerase III transcription by DNA methylation and chromatin D Varshney University of Glasgow, 2012 | 1 | 2012 |