β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells AM Malebari, D Fayne, SM Nathwani, F O’Connell, S Noorani, B Twamley, ... European Journal of Medicinal Chemistry 189, 112050, 2020 | 34 | 2020 |
High cysteinyl leukotriene receptor 1 expression correlates with poor survival of uveal melanoma patients and cognate antagonist drugs modulate the growth, cancer secretome … K Slater, AB Heeran, S Garcia-Mulero, H Kalirai, R Sanz-Pamplona, ... Cancers 12 (10), 2950, 2020 | 23 | 2020 |
Diagnostic accuracy of blood-based biomarkers for pancreatic cancer: a systematic review and meta-analysis LE Kane, GS Mellotte, E Mylod, RM O'Brien, F O'Connell, CE Buckley, ... Cancer research communications 2 (10), 1229-1243, 2022 | 22 | 2022 |
Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells M Davern, NE Donlon, A Sheppard, F O’Connell, C Hayes, A Bhardwaj, ... Translational Oncology 14 (6), 101062, 2021 | 19 | 2021 |
Gold nanoparticles and obese adipose tissue microenvironment in cancer treatment N Essa, F O'Connell, A Prina-Mello, J O'Sullivan, S Marcone Cancer Letters 525, 1-8, 2022 | 17 | 2022 |
Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines NE Donlon, A Sheppard, M Davern, F O’Connell, JJ Phelan, R Power, ... Cancers 12 (11), 3356, 2020 | 17 | 2020 |
Help or hindrance: The obesity paradox in cancer treatment response F O'Connell, J O'Sullivan Cancer Letters 522, 269-280, 2021 | 15 | 2021 |
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients M Davern, NE Donlon, F O’Connell, C Gaughan, C O’Donovan, ... Cancer Immunology, Immunotherapy 72 (1), 55-71, 2023 | 13 | 2023 |
The iron chelator desferrioxamine increases the efficacy of bedaquiline in primary human macrophages infected with BCG C Cahill, F O’Connell, KM Gogan, DJ Cox, SA Basdeo, J O’Sullivan, ... International Journal of Molecular Sciences 22 (6), 2938, 2021 | 11 | 2021 |
The impact of esophageal oncological surgery on perioperative immune function; implications for adjuvant immune checkpoint inhibition NE Donlon, M Davern, AD Sheppard, F O’Connell, MR Dunne, C Hayes, ... Frontiers in Immunology 13, 823225, 2022 | 10 | 2022 |
The omentum in obesity-associated cancer: A hindrance to effective natural killer cell migration towards tumour which can be overcome by CX3CR1 antagonism E Mylod, F O’Connell, NE Donlon, C Butler, JV Reynolds, J Lysaght, ... Cancers 14 (1), 64, 2021 | 8 | 2021 |
Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma NE Donlon, M Davern, F O’Connell, A Sheppard, A Heeran, A Bhardwaj, ... World Journal of Gastroenterology 28 (21), 2302, 2022 | 6 | 2022 |
PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming … M Davern, MC Fitzgerald, CE Buckley, AB Heeran, NE Donlon, J McGrath, ... Translational oncology 19, 101381, 2022 | 6 | 2022 |
Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy M Davern, NE Donlon, F O’Connell, C Gaughan, C O’Donovan, J McGrath, ... Journal of Cancer Research and Clinical Oncology 149 (8), 5377-5395, 2023 | 5 | 2023 |
Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma M Davern, NE Donlon, F O’Connell, AD Sheppard, C Hayes, R King, ... Translational Oncology 20, 101406, 2022 | 5 | 2022 |
The prognostic value of the lymph node in oesophageal adenocarcinoma; incorporating clinicopathological and immunological profiling NE Donlon, M Davern, A Sheppard, R Power, F O’Connell, AB Heeran, ... Cancers 13 (16), 4005, 2021 | 5 | 2021 |
Obesity, dietary fats, and gastrointestinal cancer risk-potential mechanisms relating to lipid metabolism and inflammation KAJ Mitchelson, F O’Connell, J O’Sullivan, HM Roche Metabolites 14 (1), 42, 2024 | 4 | 2024 |
Energy metabolism, metabolite, and inflammatory profiles in human ex vivo adipose tissue are influenced by obesity status, metabolic dysfunction, and treatment regimes in … F O’Connell, E Mylod, NE Donlon, AB Heeran, C Butler, A Bhardwaj, ... Cancers 15 (6), 1681, 2023 | 4 | 2023 |
The Effect of Tuberculosis Antimicrobials on the Immunometabolic Profiles of Primary Human Macrophages Stimulated with Mycobacterium tuberculosis C Cahill, DJ Cox, F O’Connell, SA Basdeo, KM Gogan, ... International Journal of Molecular Sciences 22 (22), 12189, 2021 | 4 | 2021 |
Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells M Davern, D Bracken-Clarke, NE Donlon, AD Sheppard, FO Connell, ... Journal of Cancer Research and Clinical Oncology 149 (9), 6583-6599, 2023 | 3 | 2023 |