IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice JS Cho, EM Pietras, NC Garcia, RI Ramos, DM Farzam, HR Monroe, ... The Journal of clinical investigation 120 (5), 1762-1773, 2010 | 736 | 2010 |
Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions EM Pietras, D Reynaud, YA Kang, D Carlin, FJ Calero-Nieto, AD Leavitt, ... Cell stem cell 17 (1), 35-46, 2015 | 713 | 2015 |
Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche K Schepers, EM Pietras, D Reynaud, J Flach, M Binnewies, T Garg, ... Cell stem cell 13 (3), 285-299, 2013 | 684 | 2013 |
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells J Flach, ST Bakker, M Mohrin, PC Conroy, EM Pietras, D Reynaud, ... Nature 512 (7513), 198-202, 2014 | 631 | 2014 |
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal EM Pietras, C Mirantes-Barbeito, S Fong, D Loeffler, LV Kovtonyuk, ... Nature cell biology 18 (6), 607-618, 2016 | 627 | 2016 |
Cell cycle regulation in hematopoietic stem cells EM Pietras, MR Warr, E Passegué Journal of Cell Biology 195 (5), 709-720, 2011 | 531 | 2011 |
A deubiquitinase that regulates type I interferon production N Kayagaki, Q Phung, S Chan, R Chaudhari, C Quan, KM O'Rourke, ... Science 318 (5856), 1628-1632, 2007 | 527 | 2007 |
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif SK Saha, EM Pietras, JQ He, JR Kang, SY Liu, G Oganesyan, ... The EMBO journal 25 (14), 3257-3263, 2006 | 527 | 2006 |
MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus LS Miller, RM O'Connell, MA Gutierrez, EM Pietras, A Shahangian, ... Immunity 24 (1), 79-91, 2006 | 437 | 2006 |
Inflammasome-mediated production of IL-1β is required for neutrophil recruitment against Staphylococcus aureus in vivo LS Miller, EM Pietras, LH Uricchio, K Hirano, S Rao, H Lin, RM O’Connell, ... The Journal of Immunology 179 (10), 6933-6942, 2007 | 409 | 2007 |
CD95 ligand induces motility and invasiveness of apoptosis‐resistant tumor cells BC Barnhart, P Legembre, E Pietras, C Bubici, G Franzoso, ME Peter The EMBO journal 23 (15), 3175-3185, 2004 | 364 | 2004 |
Inflammation: a key regulator of hematopoietic stem cell fate in health and disease EM Pietras Blood, The Journal of the American Society of Hematology 130 (15), 1693-1698, 2017 | 361 | 2017 |
IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development D Reynaud, E Pietras, K Barry-Holson, A Mir, M Binnewies, M Jeanne, ... Cancer cell 20 (5), 661-673, 2011 | 356 | 2011 |
Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons EM Pietras, R Lakshminarasimhan, JM Techner, S Fong, J Flach, ... Journal of Experimental Medicine 211 (2), 245-262, 2014 | 338 | 2014 |
TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging P Davizon-Castillo, B McMahon, S Aguila, D Bark, K Ashworth, A Allawzi, ... Blood, The Journal of the American Society of Hematology 134 (9), 727-740, 2019 | 239 | 2019 |
Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis C Mirantes, E Passegué, EM Pietras Experimental cell research 329 (2), 248-254, 2014 | 221 | 2014 |
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis A Hérault, M Binnewies, S Leong, FJ Calero-Nieto, SY Zhang, YA Kang, ... Nature 544 (7648), 53-58, 2017 | 190 | 2017 |
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection F Caiado, EM Pietras, MG Manz Journal of Experimental Medicine 218 (7), e20201541, 2021 | 157 | 2021 |
Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies MR Warr, EM Pietras, E Passegué Wiley Interdisciplinary Reviews: Systems Biology and Medicine 3 (6), 681-701, 2011 | 153 | 2011 |
Two CD95 tumor classes with different sensitivities to antitumor drugs A Algeciras-Schimnich, EM Pietras, BC Barnhart, P Legembre, S Vijayan, ... Proceedings of the National Academy of Sciences 100 (20), 11445-11450, 2003 | 152 | 2003 |