Enzymatic carbon–sulfur bond formation in natural product biosynthesis KL Dunbar, DH Scharf, A Litomska, C Hertweck Chemical Reviews 117 (8), 5521-5577, 2017 | 518 | 2017 |
Biosynthesis and function of gliotoxin in Aspergillus fumigatus DH Scharf, T Heinekamp, N Remme, P Hortschansky, AA Brakhage, ... Applied microbiology and biotechnology 93, 467-472, 2012 | 242 | 2012 |
Human and plant fungal pathogens: the role of secondary metabolites DH Scharf, T Heinekamp, AA Brakhage PLoS pathogens 10 (1), e1003859, 2014 | 184 | 2014 |
Transannular Disulfide Formation in Gliotoxin Biosynthesis and Its Role in Self-Resistance of the Human Pathogen Aspergillus fumigatus DH Scharf, N Remme, T Heinekamp, P Hortschansky, AA Brakhage, ... Journal of the American Chemical Society 132 (29), 10136-10141, 2010 | 166 | 2010 |
A Dedicated Glutathione S-Transferase Mediates Carbon–Sulfur Bond Formation in Gliotoxin Biosynthesis DH Scharf, N Remme, A Habel, P Chankhamjon, K Scherlach, ... Journal of the American Chemical Society 133 (32), 12322-12325, 2011 | 131 | 2011 |
Gliotoxin–bane or boon? DH Scharf, AA Brakhage, PK Mukherjee Environmental microbiology 18 (4), 1096-1109, 2016 | 129 | 2016 |
Anion receptors based on halogen bonding with halo-1, 2, 3-triazoliums R Tepper, B Schulze, M Jäger, C Friebe, DH Scharf, H Görls, ... The Journal of organic chemistry 80 (6), 3139-3150, 2015 | 116 | 2015 |
The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes M Thön, Q Al Abdallah, P Hortschansky, DH Scharf, M Eisendle, H Haas, ... Nucleic acids research 38 (4), 1098-1113, 2010 | 113 | 2010 |
Aspects on evolution of fungal β-lactam biosynthesis gene clusters and recruitment of trans-acting factors AA Brakhage, M Thön, P Spröte, DH Scharf, Q Al-Abdallah, SM Wolke, ... Phytochemistry 70 (15-16), 1801-1811, 2009 | 99 | 2009 |
Opposed Effects of Enzymatic Gliotoxin N- and S-Methylations DH Scharf, A Habel, T Heinekamp, AA Brakhage, C Hertweck Journal of the American Chemical Society 136 (33), 11674-11679, 2014 | 98 | 2014 |
Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells P Bacher, O Kniemeyer, J Teutschbein, M Thön, M Vödisch, ... The Journal of Immunology 193 (7), 3332-3343, 2014 | 81 | 2014 |
Epidithiol formation by an unprecedented twin carbon–sulfur lyase in the gliotoxin pathway DH Scharf, P Chankhamjon, K Scherlach, T Heinekamp, M Roth, ... Angewandte Chemie International Edition 51 (40), 10064-10068, 2012 | 65 | 2012 |
Epidithiodiketopiperazine biosynthesis: A four‐enzyme cascade converts glutathione conjugates into transannular disulfide bridges DH Scharf, P Chankhamjon, K Scherlach, T Heinekamp, K Willing, ... Angewandte Chemie International Edition 52 (42), 11092-11095, 2013 | 64 | 2013 |
DNA minor groove sensing and widening by the CCAAT-binding complex EM Huber, DH Scharf, P Hortschansky, M Groll, AA Brakhage Structure 20 (10), 1757-1768, 2012 | 61 | 2012 |
Flavoenzyme‐catalyzed formation of disulfide bonds in natural products DH Scharf, M Groll, A Habel, T Heinekamp, C Hertweck, AA Brakhage, ... Angewandte Chemie International Edition 53 (8), 2221-2224, 2014 | 56 | 2014 |
Star-shaped drug carriers for doxorubicin with POEGMA and POEtOxMA brush-like shells: a structural, physical, and biological comparison K Knop, D Pretzel, A Urbanek, T Rudolph, DH Scharf, A Schallon, ... Biomacromolecules 14 (8), 2536-2548, 2013 | 46 | 2013 |
Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism … P Spröte, MJ Hynes, P Hortschansky, E Shelest, DH Scharf, SM Wolke, ... Molecular microbiology 70 (2), 445-461, 2008 | 43 | 2008 |
Engineering fungal secondary metabolism: a roadmap to novel compounds DH Scharf, AA Brakhage Journal of biotechnology 163 (2), 179-183, 2013 | 41 | 2013 |
Amphiphilic star-shaped block copolymers as unimolecular drug delivery systems: investigations using a novel fungicide K Knop, GM Pavlov, T Rudolph, K Martin, D Pretzel, BO Jahn, DH Scharf, ... Soft Matter 9 (3), 715-726, 2013 | 39 | 2013 |
Structural insights into ligand recognition and activation of the melanocortin-4 receptor H Zhang, LN Chen, D Yang, C Mao, Q Shen, W Feng, DD Shen, A Dai, ... Cell Research 31 (11), 1163-1175, 2021 | 38 | 2021 |