Essential considerations for using protein–ligand structures in drug discovery GL Warren, TD Do, BP Kelley, A Nicholls, SD Warren Drug Discovery Today 17 (23-24), 1270-1281, 2012 | 187 | 2012 |
Categorizing cells on the basis of their chemical profiles: progress in single-cell mass spectrometry TJ Comi, TD Do, SS Rubakhin, JV Sweedler Journal of the American Chemical Society 139 (11), 3920-3929, 2017 | 168 | 2017 |
Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3 P Ganguly, TD Do, L Larini, NE LaPointe, AJ Sercel, MF Shade, ... The journal of physical chemistry B 119 (13), 4582-4593, 2015 | 165 | 2015 |
Amyloid β-protein assembly and Alzheimer’s disease: Dodecamers of Aβ42, but not of Aβ40, seed fibril formation NJ Economou, MJ Giammona, TD Do, X Zheng, DB Teplow, SK Buratto, ... Journal of the American Chemical Society 138 (6), 1172-1175, 2016 | 144 | 2016 |
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS) S Sangwan, A Zhao, KL Adams, CK Jayson, MR Sawaya, EL Guenther, ... Proceedings of the National Academy of Sciences 114 (33), 8770–8775, 2017 | 116 | 2017 |
Ion mobility spectrometry reveals the mechanism of amyloid formation of Aβ (25–35) and its modulation by inhibitors at the molecular level: epigallocatechin gallate and scyllo … C Bleiholder, TD Do, C Wu, NJ Economou, SS Bernstein, SK Buratto, ... Journal of the American Chemical Society 135 (45), 16926-16937, 2013 | 111 | 2013 |
Phenylalanine oligomers and fibrils: the mechanism of assembly and the importance of tetramers and counterions TD Do, WM Kincannon, MT Bowers Journal of the American Chemical Society 137 (32), 10080-10083, 2015 | 109 | 2015 |
Amyloid β-Protein C-terminal Fragments: Formation of Cylindrins and β-barrels TD Do, NE LaPointe, R Nelson, P Krotee, EY Hayden, B Ulrich, S Quan, ... Journal of the American Chemical Society 138 (2), 549-557, 2016 | 103 | 2016 |
Interactions between amyloid-β and tau fragments promote aberrant aggregates: implications for amyloid toxicity TD Do, NJ Economou, A Chamas, SK Buratto, JE Shea, MT Bowers The Journal of Physical Chemistry B 118 (38), 11220-11230, 2014 | 82 | 2014 |
A novel projection approximation algorithm for the fast and accurate computation of molecular collision cross sections (II). Model parameterization and definition of empirical … C Bleiholder, S Contreras, TD Do, MT Bowers International journal of mass spectrometry 345, 89-96, 2013 | 77 | 2013 |
Exploring the Fundamental Structures of Life: Non‐Targeted, Chemical Analysis of Single Cells and Subcellular Structures EK Neumann, TD Do, TJ Comi, JV Sweedler Angewandte Chemie International Edition 58 (28), 9348-9364, 2019 | 70 | 2019 |
Initiation of assembly of tau (273-284) and its ΔK280 mutant: an experimental and computational study L Larini, MM Gessel, NE LaPointe, TD Do, MT Bowers, SC Feinstein, ... Physical Chemistry Chemical Physics 15 (23), 8916-8928, 2013 | 67 | 2013 |
Single cell profiling using ionic liquid matrix-enhanced secondary ion mass spectrometry for neuronal cell type differentiation TD Do, TJ Comi, SJB Dunham, SS Rubakhin, JV Sweedler Analytical chemistry 89 (5), 3078-3086, 2017 | 65 | 2017 |
microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling TJ Comi, EK Neumann, TD Do, JV Sweedler Journal of The American Society for Mass Spectrometry 28 (9), 1919–1928, 2017 | 60 | 2017 |
Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure TD Do, NEC de Almeida, NE Lapointe, A Chamas, SC Feinstein, ... Analytical chemistry 88 (1), 868-876, 2016 | 53 | 2016 |
Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action HE Feinstein, SJ Benbow, NE LaPointe, N Patel, S Ramachandran, ... Journal of neurochemistry 137 (6), 939-954, 2016 | 44 | 2016 |
Effects of pH and charge state on peptide assembly: the YVIFL model system TD Do, NE LaPointe, NJ Economou, SK Buratto, SC Feinstein, JE Shea, ... The Journal of Physical Chemistry B 117 (37), 10759-10768, 2013 | 42 | 2013 |
Optically guided single cell mass spectrometry of rat dorsal root ganglia to profile lipids, peptides and proteins TD Do, JF Ellis, EK Neumann, TJ Comi, EG Tillmaand, AE Lenhart, ... ChemPhysChem 19 (10), 1180-1191, 2018 | 41 | 2018 |
Combinatorial discovery through a distributed outreach Program: Investigation of the photoelectrolysis activity of p-type Fe, Cr, Al oxides JG Rowley, TD Do, DA Cleary, BA Parkinson ACS applied materials & interfaces 6 (12), 9046-9052, 2014 | 41 | 2014 |
Tau aggregation propensity engrained in its solution state NA Eschmann, TD Do, NE LaPointe, JE Shea, SC Feinstein, MT Bowers, ... The Journal of Physical Chemistry B 119 (45), 14421-14432, 2015 | 40 | 2015 |