The DISC locus in psychiatric illness JE Chubb, NJ Bradshaw, DC Soares, DJ Porteous, JK Millar Molecular psychiatry 13 (1), 36-64, 2008 | 715 | 2008 |
SAF-A regulates interphase chromosome structure through oligomerization with chromatin-associated RNAs RS Nozawa, L Boteva, DC Soares, C Naughton, AR Dun, A Buckle, ... Cell 169 (7), 1214-1227. e18, 2017 | 194 | 2017 |
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells CJC Johnston, DJ Smyth, RB Kodali, MPJ White, Y Harcus, KJ Filbey, ... Nature communications 8 (1), 1741, 2017 | 183 | 2017 |
HpARI protein secreted by a helminth parasite suppresses interleukin-33 M Osbourn, DC Soares, F Vacca, ES Cohen, IC Scott, WF Gregory, ... Immunity 47 (4), 739-751. e5, 2017 | 169 | 2017 |
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression HM Knight, BS Pickard, A Maclean, MP Malloy, DC Soares, AF McRae, ... The American Journal of Human Genetics 85 (6), 833-846, 2009 | 164 | 2009 |
DISC1: structure, function, and therapeutic potential for major mental illness DC Soares, BC Carlyle, NJ Bradshaw, DJ Porteous ACS chemical neuroscience 2 (11), 609-632, 2011 | 159 | 2011 |
RPGR: Its role in photoreceptor physiology, human disease, and future therapies RD Megaw, DC Soares, AF Wright Experimental eye research 138, 32-41, 2015 | 131 | 2015 |
DISC1 genetics, biology and psychiatric illness PA Thomson, ELV Malavasi, E Grünewald, DC Soares, M Borkowska, ... Frontiers in biology 8, 1-31, 2013 | 130 | 2013 |
ARABIDOPSIS CRINKLY4 Function, Internalization, and Turnover Are Dependent on the Extracellular Crinkly Repeat Domain ML Gifford, FC Robertson, DC Soares, GC Ingram The Plant Cell 17 (4), 1154-1166, 2005 | 128 | 2005 |
DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking F Ogawa, ELV Malavasi, DK Crummie, JE Eykelenboom, DC Soares, ... Human molecular genetics 23 (4), 906-919, 2014 | 97 | 2014 |
Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation DC Soares, PN Barlow, HJ Newbery, DJ Porteous, CM Abbott PLoS One 4 (7), e6315, 2009 | 95 | 2009 |
Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations J Rainger, D Pehlivan, S Johansson, H Bengani, L Sanchez-Pulido, ... The American Journal of Human Genetics 94 (6), 915-923, 2014 | 91 | 2014 |
PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1 NJ Bradshaw, DC Soares, BC Carlyle, F Ogawa, H Davidson-Smith, ... Journal of Neuroscience 31 (24), 9043-9054, 2011 | 91 | 2011 |
Structural analysis of the complement control protein (CCP) modules of GABAB receptor 1a: only one of the two CCP modules is compactly folded S Blein, R Ginham, D Uhrin, BO Smith, DC Soares, S Veltel, ... Journal of Biological Chemistry 279 (46), 48292-48306, 2004 | 89 | 2004 |
Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations HG Hocking, AP Herbert, D Kavanagh, DC Soares, VP Ferreira, ... Journal of biological chemistry 283 (14), 9475-9487, 2008 | 87 | 2008 |
The intermediate filament protein, vimentin, is a regulator of NOD2 activity C Stevens, P Henderson, ER Nimmo, DC Soares, B Dogan, KW Simpson, ... Gut 62 (5), 695-707, 2013 | 86 | 2013 |
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious … JE Eykelenboom, GJ Briggs, NJ Bradshaw, DC Soares, F Ogawa, ... Human molecular genetics 21 (15), 3374-3386, 2012 | 84 | 2012 |
DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan DJ Porteous, PA Thomson, JK Millar, KL Evans, W Hennah, DC Soares, ... Molecular psychiatry 19 (2), 141-143, 2014 | 79 | 2014 |
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits PA Thomson, JS Parla, AF McRae, M Kramer, K Ramakrishnan, J Yao, ... Molecular psychiatry 19 (6), 668-675, 2014 | 70 | 2014 |
The central portion of factor H (modules 10–15) is compact and contains a structurally deviant CCP module CQ Schmidt, AP Herbert, HDT Mertens, M Guariento, DC Soares, D Uhrin, ... Journal of molecular biology 395 (1), 105-122, 2010 | 70 | 2010 |