Functional profiling of a Plasmodium genome reveals an abundance of essential genes E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ... Cell 170 (2), 260-272. e8, 2017 | 532 | 2017 |
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium A Sinha, KR Hughes, KK Modrzynska, TD Otto, C Pfander, NJ Dickens, ... Nature 507 (7491), 253-257, 2014 | 466 | 2014 |
Tetracycline-inducible gene regulation in mycobacteria MCJ Blokpoel, HN Murphy, R O'toole, S Wiles, ESC Runn, GR Stewart, ... Nucleic acids research 33 (2), e22-e22, 2005 | 228 | 2005 |
Reverse genetics screen identifies six proteins important for malaria development in the mosquito A Ecker, ESC Bushell, R Tewari, RE Sinden Molecular microbiology 70 (1), 209-220, 2008 | 153 | 2008 |
A genome-scale vector resource enables high-throughput reverse genetic screening in a malaria parasite AR Gomes, E Bushell, F Schwach, G Girling, B Anar, MA Quail, C Herd, ... Cell host & microbe 17 (3), 404-413, 2015 | 150 | 2015 |
The developmental migration of Plasmodium in mosquitoes D Vlachou, T Schlegelmilch, E Runn, A Mendes, FC Kafatos Current opinion in genetics & development 16 (4), 384-391, 2006 | 145 | 2006 |
PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites F Schwach, E Bushell, AR Gomes, B Anar, G Girling, C Herd, JC Rayner, ... Nucleic acids research 43 (D1), D1176-D1182, 2015 | 125 | 2015 |
Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage RR Stanway, E Bushell, A Chiappino-Pepe, M Roques, T Sanderson, ... Cell 179 (5), 1112-1128. e26, 2019 | 105 | 2019 |
Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals U Böhme, TD Otto, JA Cotton, S Steinbiss, M Sanders, SO Oyola, A Nicot, ... Genome research 28 (4), 547-560, 2018 | 100 | 2018 |
Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and … J Ning, TD Otto, C Pfander, F Schwach, M Brochet, E Bushell, D Goulding, ... Genes & development 27 (10), 1198-1215, 2013 | 96 | 2013 |
Global analysis of apicomplexan protein S‐acyl transferases reveals an enzyme essential for invasion K Frénal, CL Tay, C Mueller, ES Bushell, Y Jia, A Graindorge, O Billker, ... Traffic 14 (8), 895-911, 2013 | 89 | 2013 |
Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection T Brugat, AJ Reid, J Lin, D Cunningham, I Tumwine, G Kushinga, ... Nature microbiology 2 (4), 1-9, 2017 | 59 | 2017 |
Landscape of the Plasmodium Interactome Reveals Both Conserved and Species-Specific Functionality C Hillier, M Pardo, L Yu, E Bushell, T Sanderson, T Metcalf, C Herd, ... Cell reports 28 (6), 1635-1647. e5, 2019 | 51 | 2019 |
Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector ESC Bushell, A Ecker, T Schlegelmilch, D Goulding, G Dougan, ... PLoS pathogens 5 (8), e1000539, 2009 | 49 | 2009 |
Regulators of male and female sexual development are critical for the transmission of a malaria parasite AJC Russell, T Sanderson, E Bushell, AM Talman, B Anar, G Girling, ... Cell Host & Microbe, 2023 | 40 | 2023 |
Genetic susceptibility to the delayed sequelae of neonatal respiratory syncytial virus infection is MHC dependent JS Tregoning, Y Yamaguchi, B Wang, D Mihm, JA Harker, ESC Bushell, ... The Journal of Immunology 185 (9), 5384-5391, 2010 | 39 | 2010 |
Characterization of Plasmodium developmental transcriptomes in Anopheles gambiae midgut reveals novel regulators of malaria transmission KA Akinosoglou, ESC Bushell, CV Ukegbu, T Schlegelmilch, JS Cho, ... Cellular microbiology 17 (2), 254-268, 2015 | 35 | 2015 |
Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium CS Hopp, AE Balaban, ESC Bushell, O Billker, JC Rayner, P Sinnis Cellular microbiology 18 (11), 1625-1641, 2016 | 23 | 2016 |
CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact T Ishizaki, S Hernandez, MS Paoletta, T Sanderson, ESC Bushell Biochemical Society Transactions 50 (3), 1069-1079, 2022 | 13 | 2022 |
An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi EJ Marr, RM Milne, B Anar, G Girling, F Schwach, JP Mooney, ... Wellcome Open Research 5, 2020 | 13 | 2020 |