hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer C Camps, FM Buffa, S Colella, J Moore, C Sotiriou, H Sheldon, AL Harris, ... Clinical cancer research 14 (5), 1340-1348, 2008 | 781 | 2008 |
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization M Korpal, BJ Ell, FM Buffa, T Ibrahim, MA Blanco, T Celià-Terrassa, ... Nature medicine 17 (9), 1101-1108, 2011 | 715 | 2011 |
Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation K Bensaad, E Favaro, CA Lewis, B Peck, S Lord, JM Collins, KE Pinnick, ... Cell reports 9 (1), 349-365, 2014 | 616 | 2014 |
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors P Moskwa, FM Buffa, Y Pan, R Panchakshari, P Gottipati, RJ Muschel, ... Molecular cell 41 (2), 210-220, 2011 | 513 | 2011 |
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene FM Buffa, AL Harris, CM West, CJ Miller British journal of cancer 102 (2), 428-435, 2010 | 495 | 2010 |
Regulation of autophagy by ATF4 in response to severe hypoxia T Rzymski, M Milani, L Pike, F Buffa, HR Mellor, L Winchester, I Pires, ... Oncogene 29 (31), 4424-4435, 2010 | 431 | 2010 |
Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers SC Winter, FM Buffa, P Silva, C Miller, HR Valentine, H Turley, KA Shah, ... Cancer research 67 (7), 3441-3449, 2007 | 414 | 2007 |
Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells E Favaro, K Bensaad, MG Chong, DA Tennant, DJP Ferguson, C Snell, ... Cell metabolism 16 (6), 751-764, 2012 | 411 | 2012 |
microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer FM Buffa, C Camps, L Winchester, CE Snell, HE Gee, H Sheldon, ... Cancer research 71 (17), 5635-5645, 2011 | 375 | 2011 |
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU E Favaro, A Ramachandran, R McCormick, H Gee, C Blancher, M Crosby, ... PloS one 5 (4), e10345, 2010 | 353 | 2010 |
The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis HE Gee, FM Buffa, C Camps, A Ramachandran, R Leek, M Taylor, M Patil, ... British journal of cancer 104 (7), 1168-1177, 2011 | 351 | 2011 |
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival H Choudhry, A Albukhari, M Morotti, S Haider, D Moralli, J Smythies, ... Oncogene 34 (34), 4482-4490, 2015 | 345 | 2015 |
A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis M Masiero, FC Simões, HD Han, C Snell, T Peterkin, E Bridges, ... Cancer cell 24 (2), 229-241, 2013 | 300 | 2013 |
hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer HE Gee, C Camps, FM Buffa, S Patiar, SC Winter, G Betts, J Homer, ... Cancer 116 (9), 2148-2158, 2010 | 281 | 2010 |
A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer A Eustace, N Mani, PN Span, JJ Irlam, J Taylor, GNJ Betts, H Denley, ... Clinical cancer research 19 (17), 4879-4888, 2013 | 255 | 2013 |
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER T Van Den Beucken, E Koch, K Chu, R Rupaimoole, P Prickaerts, ... Nature communications 5 (1), 5203, 2014 | 236 | 2014 |
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma P Falletta, L Sanchez-del-Campo, J Chauhan, M Effern, A Kenyon, ... Genes & development 31 (1), 18-33, 2017 | 224 | 2017 |
The histone demethylase JMJD2B is regulated by estrogen receptor α and hypoxia, and is a key mediator of estrogen induced growth J Yang, AM Jubb, L Pike, FM Buffa, H Turley, D Baban, R Leek, KC Gatter, ... Cancer research 70 (16), 6456-6466, 2010 | 204 | 2010 |
The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia TM Ashton, E Fokas, LA Kunz-Schughart, LK Folkes, S Anbalagan, ... Nature communications 7 (1), 12308, 2016 | 199 | 2016 |
Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia C Camps, HK Saini, DR Mole, H Choudhry, M Reczko, ... Molecular cancer 13, 1-21, 2014 | 186 | 2014 |