BET proteins promote efficient murine leukemia virus integration at transcription start sites A Sharma, RC Larue, MR Plumb, N Malani, F Male, A Slaughter, JJ Kessl, ... Proceedings of the National Academy of Sciences 110 (29), 12036-12041, 2013 | 207 | 2013 |
Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant YZ Tan, S Aiyer, M Mietzsch, JA Hull, R McKenna, J Grieger, RJ Samulski, ... Nature communications 9 (1), 3628, 2018 | 109 | 2018 |
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction S Aiyer, GVT Swapna, N Malani, JM Aramini, WM Schneider, MR Plumb, ... Nucleic acids research 42 (9), 5917-5928, 2014 | 75 | 2014 |
Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag WM Schneider, JD Brzezinski, S Aiyer, N Malani, M Gyuricza, ... Proceedings of the National Academy of Sciences 110 (23), 9487-9492, 2013 | 50 | 2013 |
Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes RC Larue, MR Plumb, BL Crowe, N Shkriabai, A Sharma, J DiFiore, ... Nucleic acids research 42 (8), 4868-4881, 2014 | 45 | 2014 |
MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA WM Schneider, D Wu, V Amin, S Aiyer, MJ Roth Virology 426 (2), 188-196, 2012 | 30 | 2012 |
Structural and sequencing analysis of local target DNA recognition by MLV integrase S Aiyer, P Rossi, N Malani, WM Schneider, A Chandar, FD Bushman, ... Nucleic acids research 43 (11), 5647-5663, 2015 | 26 | 2015 |
Evaluating local and directional resolution of cryo-EM density maps S Aiyer, C Zhang, PR Baldwin, D Lyumkis cryoEM: Methods and Protocols, 161-187, 2021 | 21 | 2021 |
A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins S Aiyer, GVT Swapna, LC Ma, G Liu, J Hao, G Chalmers, BC Jacobs, ... Structure 29 (8), 886-898. e6, 2021 | 20 | 2021 |
Disrupting MLV integrase: BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model L Loyola, V Achuthan, K Gilroy, G Borland, A Kilbey, N Mackay, M Bell, ... PLoS pathogens 15 (12), e1008154, 2019 | 13 | 2019 |
X‐ray crystal structure of the N‐terminal region of M oloney murine leukemia virus integrase and its implications for viral DNA recognition R Guan, S Aiyer, ML Cote, R Xiao, M Jiang, TB Acton, MJ Roth, ... Proteins: Structure, Function, and Bioinformatics 85 (4), 647-656, 2017 | 12 | 2017 |
Development of an enzyme-linked immunosorbent assay based on the murine leukemia virus p30 capsid protein DT Wu, S Aiyer, RA Villanueva, MJ Roth Journal of virological methods 193 (2), 332-336, 2013 | 10 | 2013 |
B-to-A transition in target DNA during retroviral integration IK Jóźwik, W Li, DW Zhang, D Wong, J Grawenhoff, A Ballandras-Colas, ... Nucleic Acids Research 50 (15), 8898-8918, 2022 | 8 | 2022 |
Single-particle cryo-EM data collection with stage tilt using leginon S Aiyer, TS Strutzenberg, ME Bowman, JP Noel, D Lyumkis JoVE (Journal of Visualized Experiments), e64136, 2022 | 5 | 2022 |
Overcoming resolution attenuation during tilted cryo-EM data collection S Aiyer, PR Baldwin, SM Tan, Z Shan, J Oh, A Mehrani, ME Bowman, ... Nature communications 15 (1), 389, 2024 | 3 | 2024 |
Assembly of the Bacterial Ribosome with Circularly Permuted rRNA X Dong, K Sheng, LFR Gebert, S Aiyer, IJ MacRae, D Lyumkis, ... bioRxiv, 2024 | 1 | 2024 |
Domain consolidation in Bacterial 50S assembly revealed by Anti-Sense Oligonucleotide Probing K Sheng, X Dong, S Aiyer, J Lee, SD Marquardt, D Lyumkis, ... bioRxiv, 2024 | | 2024 |
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding T Jing, Z Shan, T Dinh, A Biswas, S Jang, J Greenwood, M Li, Z Zhang, ... bioRxiv, 2024 | | 2024 |
Anisotropy in CryoEM Resolution is Dominated by Preferred Orientations, but not Structure Factors: A Study Using a Highly Symmetric Structure PR Baldwin, S Aiyer, TS Strutzenberg, D Lyumkis Microscopy and Microanalysis 29 (Supplement_1), 1021-1023, 2023 | | 2023 |
AAV Capsid Dynamics at the 5-Fold Pore Controls Genome Release JA Hull, M Mietzsch, YZ Tan, S Aiyer, A Bennett, R Lakshman, P Chipman, ... MOLECULAR THERAPY 30 (4), 205-206, 2022 | | 2022 |