关注
Jiajun Dong
Jiajun Dong
Postdoctoral Researcher, UF Scripps
在 ufl.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Systemic inhibition of PTPN22 augments anticancer immunity
WJ Ho, S Croessmann, J Lin, ZH Phyo, S Charmsaz, L Danilova, ...
The Journal of Clinical Investigation 131 (17), 2021
332021
Bioresponsive albumin-conjugated paclitaxel prodrugs for cancer therapy
J Yang, Q Lv, W Wei, Z Yang, J Dong, R Zhang, Q Kan, Z He, Y Xu
Drug Delivery 25 (1), 807-814, 2018
332018
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
S Liang, E Tran, X Du, J Dong, H Sudholz, H Chen, Z Qu, ND Huntington, ...
Nature Communications 14 (1), 4524, 2023
312023
Small molecule degraders of protein tyrosine phosphatase 1B and T‐cell protein tyrosine phosphatase for cancer immunotherapy
J Dong, J Miao, Y Miao, Z Qu, S Zhang, P Zhu, F Wiede, BA Jassim, Y Bai, ...
Angewandte Chemie International Edition 62 (22), e202303818, 2023
202023
SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease
CD Jesudason, ER Mason, S Chu, AL Oblak, J Javens‐Wolfe, M Moussaif, ...
Alzheimer's & Dementia: Translational Research & Clinical Interventions 9 (4 …, 2023
52023
Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity
J Miao, Y Bai, Y Miao, Z Qu, J Dong, RY Zhang, D Aggarwal, BA Jassim, ...
Molecules 28 (19), 6947, 2023
42023
Discovery of a selective TC-PTP degrader for cancer immunotherapy
J Miao, J Dong, Y Miao, Y Bai, Z Qu, BA Jassim, B Huang, Q Nguyen, ...
Chemical Science 14 (44), 12606-12614, 2023
42023
Targeted covalent inhibition of small CTD phosphatase 1 to promote the degradation of the REST Transcription factor in human cells
B Medellin, W Yang, S Konduri, J Dong, S Irani, H Wu, WL Matthews, ...
Journal of medicinal chemistry 65 (1), 507-519, 2021
42021
Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases
J Dong, BA Jassim, KL Milholland, Z Qu, Y Bai, Y Miao, J Miao, Y Ma, ...
Journal of Medicinal Chemistry, 2024
22024
A target enablement package for the inhibition of SHIP1 as a therapeutic strategy for the treatment of Alzheimer’s disease
TI Richardson, CD Jesudason, KL Lobb, GL Durst, B Clayton, SM Massey, ...
Alzheimer's & Dementia 18, e068781, 2022
22022
Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers
Y Miao, Y Bai, J Miao, AA Murray, J Lin, J Dong, Z Qu, RY Zhang, ...
The Journal of Clinical Investigation 134 (15), 2024
2024
Discovery of a cebrelon-based PTPN1/PTPN2 dual targeting degrader for cancer immunotherapy
Z Qu, Y Bai, J Dong, Z Zhang, B Huang, Y Miao, AW Tao, PS Low, ...
Cancer Research 84 (6_Supplement), 4505-4505, 2024
2024
Discovery of the first-in-class SHP1 covalent inhibitor for cancer immunotherapy
Z Qu, FN Meke, Z Zhang, Y Bai, AD Krabill, CS Muli, BA Jassim, J Dong, ...
Cancer Research 84 (6_Supplement), 1973-1973, 2024
2024
Off-target autophagy inhibition by SHP2 allosteric inhibitors and therapeutic implications for aberrant RAS-driven cancers
Y Miao, Y Bai, J Miao, AA Murray, J Lin, J Dong, Z Qu, RY Zhang, ...
Cancer Research 84 (6_Supplement), 1969-1969, 2024
2024
Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
Z Qu, J Dong, ZY Zhang
British Journal of Pharmacology, 2023
2023
Discovery and Evaluation of Novel Ship-1 Inhibitors
ZY Zhang, J Miao, J Lin, J Dong, O Amarasinghe, ER Mason, S Chu, Z Qu, ...
Available at SSRN 4934996, 0
系统目前无法执行此操作,请稍后再试。
文章 1–16