| Pathway and mechanism of drug binding to G-protein-coupled receptors RO Dror, AC Pan, DH Arlow, DW Borhani, P Maragakis, Y Shan, H Xu, ... Proceedings of the National Academy of Sciences 108 (32), 13118-13123, 2011 | 812 | 2011 |
| Mechanism of voltage gating in potassium channels MO Jensen, V Jogini, DW Borhani, AE Leffler, RO Dror, DE Shaw Science 336 (6078), 229, 2012 | 645 | 2012 |
| Activation mechanism of the β2-adrenergic receptor RO Dror, DH Arlow, P Maragakis, TJ Mildorf, AC Pan, H Xu, DW Borhani, ... Proceedings of the National Academy of Sciences 108 (46), 18684-18689, 2011 | 634 | 2011 |
| Crystal structure of truncated human apolipoprotein AI suggests a lipid-bound conformation DW Borhani, DP Rogers, JA Engler, CG Brouillette Proceedings of the National Academy of Sciences 94 (23), 12291-12296, 1997 | 596 | 1997 |
| Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ... Nature 503 (7475), 295-299, 2013 | 433 | 2013 |
| Crystal structure of the ectodomain of human transferrin receptor CM Lawrence, S Ray, M Babyonyshev, R Galluser, DW Borhani, ... Science 286 (5440), 779-782, 1999 | 424 | 1999 |
| Molecular determinants of drug–receptor binding kinetics AC Pan, DW Borhani, RO Dror, DE Shaw Drug discovery today 18 (13-14), 667-673, 2013 | 410 | 2013 |
| Identification Of Two Distinct Inactive Conformations Of The Beta-2 Adrenergic Receptor Reconciles Structural And Biochemical Observations RO Dror, DH Arlow, DW Borhani, M Jensen, DE Shaw Biophysical Journal 96 (3), 365a, 2009 | 376 | 2009 |
| The future of molecular dynamics simulations in drug discovery DW Borhani, DE Shaw Journal of computer-aided molecular design 26, 15-26, 2012 | 370 | 2012 |
| Principles of conduction and hydrophobic gating in K+ channels MØ Jensen, DW Borhani, K Lindorff-Larsen, P Maragakis, V Jogini, ... Proceedings of the National Academy of Sciences 107 (13), 5833-5838, 2010 | 367 | 2010 |
| Structural models of human apolipoprotein AI: a critical analysis and review CG Brouillette, GM Anantharamaiah, JA Engler, DW Borhani Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2001 | 348 | 2001 |
| Structural basis for nucleotide exchange in heterotrimeric G proteins RO Dror, TJ Mildorf, D Hilger, A Manglik, DW Borhani, DH Arlow, ... Science 348 (6241), 1361-1365, 2015 | 316 | 2015 |
| Crystalline anti-hTNFalpha antibodies DW Borhani, W Fraunhofer, HJ Krause, A Koenigsdorfer, G Winter, ... US Patent 8,034,906, 2011 | 249 | 2011 |
| Exploring atomic resolution physiology on a femtosecond to millisecond timescale using molecular dynamics simulations RO Dror, MØ Jensen, DW Borhani, DE Shaw Journal of General Physiology 135 (6), 555-562, 2010 | 195 | 2010 |
| Compositions and methods for crystallizing antibodies W Fraunhofer, DW Borhani, G Winter, S Gottschalk US Patent 8,753,839, 2014 | 173 | 2014 |
| The crystal structure of the aldose reductase. NADPH binary complex. DW Borhani, TM Harter, JM Petrash Journal of Biological Chemistry 267 (34), 24841-24847, 1992 | 164 | 1992 |
| Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110. I Tarle, DW Borhani, DK Wilson, FA Quiocho, JM Petrash Journal of Biological Chemistry 268 (34), 25687-25693, 1993 | 155 | 1993 |
| Slow Polymerization of Mycobacterium tuberculosis FtsZ EL White, LJ Ross, RC Reynolds, LE Seitz, GD Moore, DW Borhani Journal of Bacteriology 182 (14), 4028-4034, 2000 | 148 | 2000 |
| A high yield purification of the human transferrin receptor and properties of its major extracellular fragment. AP Turkewitz, JF Amatruda, D Borhani, SC Harrison, AL Schwartz Journal of Biological Chemistry 263 (17), 8318-8325, 1988 | 140 | 1988 |
| Structure of<i> Mycobacterium tuberculosis</i> FtsZ Reveals Unexpected, G Protein-like Conformational Switches AKW Leung, E Lucile White, LJ Ross, RC Reynolds, JA DeVito, ... Journal of molecular biology 342 (3), 953-970, 2004 | 138 | 2004 |
