A chemical toolbox for the study of bromodomains and epigenetic signaling Q Wu, D Heidenreich, S Zhou, S Ackloo, A Krämer, K Nakka, ... Nature communications 10 (1), 1-14, 2019 | 122 | 2019 |
Discovery of an MLLT1/3 YEATS domain chemical probe M Moustakim, T Christott, OP Monteiro, J Bennett, C Giroud, J Ward, ... Angewandte Chemie International Edition 57 (50), 16302-16307, 2018 | 73 | 2018 |
Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity E Watts, D Heidenreich, E Tucker, M Raab, K Strebhardt, L Chesler, ... Journal of medicinal chemistry 62 (5), 2618-2637, 2019 | 57 | 2019 |
Discovery and optimization of a selective ligand for the switch/sucrose nonfermenting-related bromodomains of polybromo protein-1 by the use of virtual screening and hydration … V Myrianthopoulos, N Gaboriaud-Kolar, C Tallant, ML Hall, S Grigoriou, ... Journal of medicinal chemistry 59 (19), 8787-8803, 2016 | 56 | 2016 |
Selective targeting of bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation JC Meier, C Tallant, O Fedorov, H Witwicka, SY Hwang, RG van Stiphout, ... ACS chemical biology 12 (10), 2619-2630, 2017 | 43 | 2017 |
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL) D Heidenreich, M Moustakim, J Schmidt, D Merk, PE Brennan, O Fedorov, ... Journal of medicinal chemistry 61 (23), 10929-10934, 2018 | 40 | 2018 |
Pan-SMARCA/PB1 bromodomain inhibitors and their role in regulating adipogenesis M Wanior, F Preuss, X Ni, A Krämer, S Mathea, T Göbel, ... Journal of medicinal chemistry 63 (23), 14680-14699, 2020 | 26 | 2020 |
Structural insights into interaction mechanisms of alternative piperazine-urea YEATS domain binders in MLLT1 X Ni, D Heidenreich, T Christott, J Bennett, M Moustakim, PE Brennan, ... ACS Medicinal Chemistry Letters 10 (12), 1661-1666, 2019 | 26 | 2019 |
Protein 19F-labeling using transglutaminase for the NMR study of intermolecular interactions Y Hattori, D Heidenreich, Y Ono, T Sugiki, K Yokoyama, E Suzuki, ... Journal of biomolecular NMR 68 (4), 271-279, 2017 | 19 | 2017 |
Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor LA Dutra, D Heidenreich, GDB Silva, C Man Chin, S Knapp, JL Santos Nutrients 9 (11), 1172, 2017 | 17 | 2017 |
Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage‐Induced, Histone Post‐Translational Modification MP Jacinto, D Heidenreich, S Müller, MM Greenberg ChemBioChem 23 (22), e202200373, 2022 | | 2022 |
Entdeckung einer chemischen Sonde für MLLT1/3‐YEATS‐Domänen M Moustakim, T Christott, OP Monteiro, J Bennett, C Giroud, J Ward, ... Angewandte Chemie 130 (50), 16540-16545, 2018 | | 2018 |