Review on modern advances of chemical methods for the introduction of a phosphonic acid group CS Demmer, N Krogsgaard-Larsen, L Bunch Chemical reviews 111 (12), 7981-8006, 2011 | 563 | 2011 |
A General and Convenient Method for the Rhodium‐Catalyzed Decarbonylation of Aldehydes M Kreis, A Palmelund, L Bunch, R Madsen Advanced Synthesis & Catalysis 348 (15), 2148-2154, 2006 | 172 | 2006 |
Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy E Boedtkjer, L Bunch, S F Pedersen Current pharmaceutical design 18 (10), 1345-1371, 2012 | 158 | 2012 |
Benzoxazoles and oxazolopyridines in medicinal chemistry studies CS Demmer, L Bunch European Journal of Medicinal Chemistry 97, 778-785, 2015 | 152 | 2015 |
Structure− activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5, 6 … MN Erichsen, THV Huynh, B Abrahamsen, JF Bastlund, C Bundgaard, ... Journal of medicinal chemistry 53 (19), 7180-7191, 2010 | 135 | 2010 |
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1 AA Jensen, MN Erichsen, CW Nielsen, TB Stensbøl, J Kehler, L Bunch Journal of medicinal chemistry 52 (4), 912-915, 2009 | 102 | 2009 |
Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities AA Jensen, C Fahlke, WE Bjørn-Yoshimoto, L Bunch Current opinion in pharmacology 20, 116-123, 2015 | 95 | 2015 |
Excitatory amino acid transporters as potential drug targets L Bunch, MN Erichsen, AA Jensen Expert opinion on therapeutic targets 13 (6), 719-731, 2009 | 93 | 2009 |
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in … B Abrahamsen, N Schneider, MN Erichsen, THV Huynh, C Fahlke, ... Journal of Neuroscience 33 (3), 1068-1087, 2013 | 66 | 2013 |
Chemo-Enzymatic Synthesis of a Series of 2,4-Syn-Functionalized (S)-Glutamate Analogues: New Insight into the Structure−Activity Relation of Ionotropic … E Sagot, DS Pickering, X Pu, M Umberti, TB Stensbøl, B Nielsen, ... Journal of medicinal chemistry 51 (14), 4093-4103, 2008 | 66 | 2008 |
A multifaceted GABAA receptor modulator: functional properties and mechanism of action of the sedative-hypnotic and recreational drug methaqualone (quaalude) H Hammer, BM Bader, C Ehnert, C Bundgaard, L Bunch, ... Molecular pharmacology 88 (2), 401-420, 2015 | 63 | 2015 |
Subtype selective kainic acid receptor agonists: discovery and approaches to rational design L Bunch, P Krogsgaard‐Larsen Medicinal research reviews 29 (1), 3-28, 2009 | 62 | 2009 |
Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors MB Hermit, JR Greenwood, B Nielsen, L Bunch, CG Jørgensen, ... European journal of pharmacology 486 (3), 241-250, 2004 | 60 | 2004 |
Rational Design, Synthesis, and Pharmacological Evaluation of 2-Azanorbornane-3-exo,5-endo-dicarboxylic Acid: A Novel Conformationally Restricted Glutamic … L Bunch, T Liljefors, JR Greenwood, K Frydenvang, H Bräuner-Osborne, ... The Journal of Organic Chemistry 68 (4), 1489-1495, 2003 | 60 | 2003 |
Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and … THV Huynh, B Abrahamsen, KK Madsen, A Gonzalez-Franquesa, ... Bioorganic & medicinal chemistry 20 (23), 6831-6839, 2012 | 57 | 2012 |
Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1− 3 S Alaux, M Kusk, E Sagot, J Bolte, AA Jensen, H Bräuner-Osborne, ... Journal of medicinal chemistry 48 (25), 7980-7992, 2005 | 53 | 2005 |
Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate … Z Assaf, AP Larsen, R Venskutonytė, L Han, B Abrahamsen, B Nielsen, ... Journal of medicinal chemistry 56 (4), 1614-1628, 2013 | 50 | 2013 |
Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transporters H Bräuner-Osborne, L Bunch, N Chopin, F Couty, G Evano, AA Jensen, ... Organic & biomolecular chemistry 3 (21), 3926-3936, 2005 | 47 | 2005 |
Heterocycles as Nonclassical Bioisosteres of α‐Amino Acids CBM Poulie, L Bunch ChemMedChem 8 (2), 205-215, 2013 | 41 | 2013 |
Stereoselective Chemoenzymatic Synthesis of the Four Stereoisomers of l-2-(2-Carboxycyclobutyl)glycine and Pharmacological Characterization at Human … S Faure, AA Jensen, V Maurat, X Gu, E Sagot, DJ Aitken, J Bolte, ... Journal of medicinal chemistry 49 (22), 6532-6538, 2006 | 41 | 2006 |