Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine S Rajamani, LL Eckhardt, CR Valdivia, CA Klemens, BM Gillman, ... British journal of pharmacology 149 (5), 481-489, 2006 | 237 | 2006 |
Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome AS Amin, LJ Herfst, BP Delisle, CA Klemens, MB Rook, CR Bezzina, ... The Journal of clinical investigation 118 (7), 2552-2561, 2008 | 116 | 2008 |
Arrhythmogenic Remodeling of β2 Versus β1 Adrenergic Signaling in the Human Failing Heart D Lang, K Holzem, C Kang, M Xiao, HJ Hwang, GA Ewald, KA Yamada, ... Circulation: Arrhythmia and Electrophysiology 8 (2), 409-419, 2015 | 102 | 2015 |
Associations between clinical diagnostic criteria and pretreatment patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic … J Balderman, K Holzem, BJ Field, MM Bottros, AA Abuirqeba, C Vemuri, ... Journal of Vascular Surgery 66 (2), 533-544. e2, 2017 | 67 | 2017 |
Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure KM Holzem, JF Gomez, AV Glukhov, EJ Madden, AC Koppel, GA Ewald, ... Journal of molecular and cellular cardiology 96, 82-92, 2016 | 49 | 2016 |
Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease B Hsueh, VM Burns, P Pauerstein, K Holzem, L Ye, K Engberg, AC Wang, ... Scientific reports 7 (1), 5899, 2017 | 38 | 2017 |
Right ventricular arrhythmogenesis in failing human heart: the role of conduction and repolarization remodeling Q Lou, DL Janks, KM Holzem, D Lang, B Onal, CM Ambrosi, VV Fedorov, ... American Journal of Physiology-Heart and Circulatory Physiology 303 (12 …, 2012 | 36 | 2012 |
Three-dimensional printing physiology laboratory technology MS Sulkin, E Widder, C Shao, KM Holzem, C Gloschat, SR Gutbrod, ... American Journal of Physiology-Heart and Circulatory Physiology 305 (11 …, 2013 | 30 | 2013 |
Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts KM Holzem, KC Vinnakota, VK Ravikumar, EJ Madden, GA Ewald, ... The FASEB journal 30 (8), 2698, 2016 | 26 | 2016 |
Adverse remodeling of the electrophysiological response to ischemia–reperfusion in human heart failure is associated with remodeling of metabolic gene expression FS Ng, KM Holzem, AC Koppel, D Janks, F Gordon, AL Wit, NS Peters, ... Circulation: Arrhythmia and Electrophysiology 7 (5), 875-882, 2014 | 26 | 2014 |
Arrhythmogenic remodelling of activation and repolarization in the failing human heart KM Holzem, IR Efimov Europace 14 (suppl_5), v50-v57, 2012 | 26 | 2012 |
Properties of WT and mutant hERG K+ channels expressed in neonatal mouse cardiomyocytes EC Lin, KM Holzem, BD Anson, BM Moungey, SY Balijepalli, DJ Tester, ... American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010 | 23 | 2010 |
Diet‐induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload KM Holzem, JT Marmerstein, EJ Madden, IR Efimov Physiological reports 3 (8), e12489, 2015 | 21 | 2015 |
Arrhythmogenic and metabolic remodelling of failing human heart CR Gloschat, AC Koppel, KK Aras, JA Brennan, KM Holzem, IR Efimov The Journal of Physiology 594 (14), 3963-3980, 2016 | 20 | 2016 |
Nanoscale three-dimensional imaging of the human myocyte MS Sulkin, F Yang, KM Holzem, B Van Leer, C Bugge, JI Laughner, ... Journal of structural biology 188 (1), 55-60, 2014 | 17 | 2014 |
Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation KM Holzem, EJ Madden, IR Efimov Europace 16 (suppl_4), iv77-iv85, 2014 | 9 | 2014 |
Surgical planning with three-dimensional printing of a complex renal artery aneurysm KM Holzem, S Jayarajan, MA Zayed Journal of Vascular Surgery Cases, Innovations and Techniques 4 (1), 19, 2018 | 7 | 2018 |
The role of IKr in transmural repolarization abnormalities in human heart failure KM Holzem, AV Glukhov, IR Efimov Circulation 124 (suppl_21), A16014-A16014, 2011 | 7 | 2011 |
New cardiac magnetic resonance imaging modalities aid in the detection of myocardial fibrosis KM Holzem Physiological Reports 5 (6), 2017 | 1 | 2017 |
Remodeling of Energetics and Electrophysiology in Cardiac Hypertrophy and Failure: from Function to Structure KM Holzem Washington University in St. Louis, 2017 | 1 | 2017 |