Repair of a DNA-protein crosslink by replication-coupled proteolysis JP Duxin, JM Dewar, H Yardimci, JC Walter Cell 159 (2), 346-357, 2014 | 240 | 2014 |
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein JP Duxin, B Dao, P Martinsson, N Rajala, L Guittat, JL Campbell, ... Molecular and cellular biology 29 (15), 4274-4282, 2009 | 217 | 2009 |
Replication-coupled DNA-protein crosslink repair by SPRTN and the proteasome in Xenopus egg extracts NB Larsen, AO Gao, JL Sparks, I Gallina, RA Wu, M Mann, M Räschle, ... Molecular cell 73 (3), 574-588. e7, 2019 | 170 | 2019 |
The CMG helicase bypasses DNA-protein cross-links to facilitate their repair JL Sparks, G Chistol, AO Gao, M Räschle, NB Larsen, M Mann, JP Duxin, ... Cell 176 (1), 167-181. e21, 2019 | 154 | 2019 |
What is the DNA repair defect underlying Fanconi anemia? JP Duxin, JC Walter Current opinion in cell biology 37, 49-60, 2015 | 153 | 2015 |
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network KK Karanja, SW Cox, JP Duxin, SA Stewart, JL Campbell Cell cycle 11 (21), 3983-3996, 2012 | 107 | 2012 |
FEN1 ensures telomere stability by facilitating replication fork re-initiation A Saharia, DC Teasley, JP Duxin, B Dao, KB Chiappinelli, SA Stewart Journal of Biological Chemistry 285 (35), 27057-27066, 2010 | 85 | 2010 |
Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication JP Duxin, HR Moore, J Sidorova, K Karanja, Y Honaker, B Dao, ... Journal of Biological Chemistry 287 (26), 21980-21991, 2012 | 69 | 2012 |
Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS T Nittis, L Guittat, RD LeDuc, B Dao, JP Duxin, H Rohrs, RR Townsend, ... Molecular & Cellular Proteomics 9 (6), 1144-1156, 2010 | 62 | 2010 |
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis I Gallina, IA Hendriks, S Hoffmann, NB Larsen, J Johansen, ... Molecular Cell 81 (3), 442-458. e9, 2021 | 58 | 2021 |
Dynamics of the eukaryotic replicative helicase at lagging-strand protein barriers support the steric exclusion model HB Kose, NB Larsen, JP Duxin, H Yardimci Cell Reports 26 (8), 2113-2125. e6, 2019 | 47 | 2019 |
Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway JCY Liu, U Kühbacher, NB Larsen, N Borgermann, DH Garvanska, ... The EMBO journal 40 (18), e107413, 2021 | 45 | 2021 |
How to fix DNA-protein crosslinks U Kühbacher, JP Duxin DNA repair 94, 102924, 2020 | 38 | 2020 |
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination SM Ambjørn, JP Duxin, EPT Hertz, I Nasa, J Duro, T Kruse, ... Nature communications 12 (1), 5748, 2021 | 34 | 2021 |
Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide RP Fuchs, A Isogawa, JA Paulo, K Onizuka, T Takahashi, R Amunugama, ... Elife 10, e69544, 2021 | 17 | 2021 |
SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway L Schubert, IA Hendriks, EPT Hertz, W Wu, S Sellés‐Baiget, S Hoffmann, ... EMBO reports 23 (4), e53639, 2022 | 15 | 2022 |
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene Y Gao, L Guitton-Sert, J Dessapt, Y Coulombe, A Rodrigue, L Milano, ... Nature Communications 14 (1), 381, 2023 | 10 | 2023 |
Targeting DNA-Protein Crosslinks via Post-Translational Modifications X Leng, JP Duxin Frontiers in Molecular Biosciences 9, 944775, 2022 | 10 | 2022 |
A safe fix for alcohol-derived DNA damage I Gallina, JP Duxin Nature 579 (7800), 499-500, 2020 | 8 | 2020 |
Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1 CS Colding-Christensen, ES Kakulidis, J Arroyo-Gomez, IA Hendriks, ... Nature Communications 14 (1), 8293, 2023 | 2 | 2023 |