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Kristin A. Altwegg
Kristin A. Altwegg
NIH-NCATS / FDA
在 nih.gov 的电子邮件经过验证 - 首页
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引用次数
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EC359: a first-in-class small-molecule inhibitor for targeting oncogenic LIFR signaling in triple-negative breast cancer
S Viswanadhapalli, Y Luo, GR Sareddy, B Santhamma, M Zhou, M Li, ...
Molecular cancer therapeutics 18 (8), 1341-1354, 2019
592019
LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer
W Tang, K Ramasamy, SMA Pillai, B Santhamma, S Konda, ...
Cell Death Discovery 7 (1), 216, 2021
192021
SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance
Z Liu, J Liu, B Ebrahimi, UP Pratap, Y He, KA Altwegg, W Tang, X Li, Z Lai, ...
Breast Cancer Research 24 (1), 26, 2022
182022
LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer
M Li, S Viswanadhapalli, B Santhamma, UP Pratap, Y Luo, J Liu, ...
Communications Biology 4 (1), 1235, 2021
172021
Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling
J Liu, Z Liu, M Li, W Tang, UP Pratap, Y Luo, KA Altwegg, X Li, Y Zou, ...
Molecular oncology 15 (4), 1146-1161, 2021
152021
Role of estrogen receptor coregulators in endocrine resistant breast cancer
KA Altwegg, RK Vadlamudi
Exploration of targeted anti-tumor therapy 2 (4), 385, 2021
132021
PELP1 signaling contributes to medulloblastoma progression by regulating the NF‐κB pathway
Y Luo, M Li, UP Pratap, S Viswanadhapalli, J Liu, PP Venkata, ...
Molecular carcinogenesis 59 (3), 281-292, 2020
122020
Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma
UP Pratap, GR Sareddy, Z Liu, PP Venkata, J Liu, W Tang, KA Altwegg, ...
Neuro-Oncology Advances 3 (1), vdab099, 2021
112021
A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer
KA Altwegg, S Viswanadhapalli, M Mann, D Chakravarty, S Krishnan, ...
Cancer research 82 (20), 3830-3844, 2022
102022
Global genomic and proteomic analysis identified critical pathways modulated by proto-oncogene PELP1 in TNBC
Z Liu, KA Altwegg, J Liu, ST Weintraub, Y Chen, Z Lai, GR Sareddy, ...
Cancers 14 (4), 930, 2022
62022
Inhibition of LIFR blocks adiposity-driven endometrioid endometrial cancer growth
L Blankenship, UP Pratap, X Yang, Z Liu, KA Altwegg, B Santhamma, ...
Cancers 14 (21), 5400, 2022
52022
PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis
X Yang, Z Liu, W Tang, UP Pratap, AB Collier, KA Altwegg, R Gopalam, ...
Molecular oncology 18 (9), 2136-2156, 2024
42024
Targeting PELP1 oncogenic signaling in TNBC with the small molecule inhibitor SMIP34
KA Altwegg, UP Pratap, Z Liu, J Liu, JR Sanchez, X Yang, B Ebrahimi, ...
Breast Cancer Research and Treatment 200 (1), 151-162, 2023
32023
HDAC inhibitors enhance ERβ expression and augment ERβ agonist mediated tumor suppression in glioblastoma
UP Pratap, S Gangadhara, Z Liu, VP Venkata, J Liu, W Tang, K Altwegg, ...
Neuro Oncol Adv 3 (1), vdab099, 2021
22021
A novel small molecule targeting oncogenic PELP1 demonstrates anti-tumor activity in wild-type and mutant ER-positive breast cancer
KA Altwegg, M Mann, D Chakravarty, Z Liu, J Liu, UP Pratap, B Ebrahimi, ...
Cancer Research 82 (12_Supplement), 648-648, 2022
12022
PELP1-TFAP2C crosstalk promotes endocrine resistance in breast cancer cells
J Liu, S Viswanadhapalli, M Li, UP Pratap, W Tang, Z Liu, Y Luo, ...
Cancer Research 80 (16_Supplement), 4371-4371, 2020
12020
778 Designing and utilizing a c-Rel specific bioassay in drug repurposing screen for HNSCC
KA Altwegg, K King, D Blivis, T Voss, NJ Martinez, MJ Henderson, ...
Journal of Investigative Dermatology 144 (8), S136, 2024
2024
Developing a drug repurposing screen for head and neck squamous cell carcinoma using a novel c-Rel bioassay
KA Altwegg, KE King, D Blivis, TC Voss, NJ Martinez, WC Weinberg, ...
Cancer Research 84 (6_Supplement), 3101-3101, 2024
2024
Leukemia inhibitory factor receptor inhibition reduces obesity driven progression of triple negative breast cancer
S Viswanadhapalli, UP Pratap, B Ebrahimi, L Blankenship, J Joshi, Z Liu, ...
CANCER RESEARCH 82 (4), 2022
2022
Abstract P5-10-01: Leukemia inhibitory factor receptor inhibition reduces obesity driven progression of triple negative breast cancer
S Viswanadhapalli, UP Pratap, B Ebrahimi, L Blankenship, J Joshi, Z Liu, ...
Cancer Research 82 (4_Supplement), P5-10-01-P5-10-01, 2022
2022
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