Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion W He, H Wan, L Hu, P Chen, X Wang, Z Huang, ZH Yang, CQ Zhong, ... Cell research 25 (12), 1285-1298, 2015 | 2024 | 2015 |
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1349 | 2020 |
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death X Chen, W Li, J Ren, D Huang, W He, Y Song, C Yang, W Li, X Zheng, ... Cell research 24 (1), 105-121, 2014 | 797 | 2014 |
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis X Chen, W He, L Hu, J Li, Y Fang, X Wang, X Xu, Z Wang, K Huang, J Han Cell research 26 (9), 1007-1020, 2016 | 697 | 2016 |
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection G Song, W He, S Callaghan, F Anzanello, D Huang, J Ricketts, JL Torres, ... Nature communications 12 (1), 2938, 2021 | 283 | 2021 |
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... Science translational medicine 14 (637), eabi9215, 2022 | 136 | 2022 |
The MLKL channel in necroptosis is an octamer formed by tetramers in a dyadic process D Huang, X Zheng, Z Wang, X Chen, W He, Y Zhang, JG Xu, H Zhao, ... Molecular and cellular biology 37 (5), e00497-16, 2017 | 136 | 2017 |
Site-specific steric control of SARS-CoV-2 spike glycosylation JD Allen, H Chawla, F Samsudin, L Zuzic, AT Shivgan, Y Watanabe, ... Biochemistry 60 (27), 2153-2169, 2021 | 67 | 2021 |
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu, VT Longping, ... Immunity 56 (3), 669-686. e7, 2023 | 56 | 2023 |
A broad and potent neutralization epitope in SARS-related coronaviruses M Yuan, X Zhu, W He, P Zhou, CI Kaku, T Capozzola, CY Zhu, X Yu, H Liu, ... Proceedings of the National Academy of Sciences 119 (29), e2205784119, 2022 | 48 | 2022 |
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses W He, R Musharrafieh, G Song, K Dueker, LV Tse, DR Martinez, ... Nature immunology 23 (6), 960-970, 2022 | 46 | 2022 |
A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... | 34 | 2021 |
pelo Is Required for High Efficiency Viral Replication X Wu, WT He, S Tian, D Meng, Y Li, W Chen, L Li, L Tian, CQ Zhong, ... PLoS Pathogens 10 (4), e1004034, 2014 | 28 | 2014 |
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ... Science translational medicine 14 (657), eabl9605, 2022 | 24 | 2022 |
The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2 JD Allen, DP Ivory, SG Song, W He, T Capozzola, P Yong, DR Burton, ... Cell reports 42 (4), 2023 | 9 | 2023 |
A rapid assay for SARS-CoV-2 neutralizing antibodies that is insensitive to antiretroviral drugs D Huang, JT Tran, L Peng, L Yang, RT Suhandynata, MA Hoffman, ... The Journal of Immunology 207 (1), 344-351, 2021 | 5 | 2021 |
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes J Hurtado, TF Rogers, DB Jaffe, BA Adams, S Bangaru, E Garcia, ... Cell Reports 43 (6), 2024 | 3 | 2024 |
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift G Song, M Yuan, H Liu, T Capozzola, RN Lin, JL Torres, W He, ... bioRxiv, 2023 | 2 | 2023 |
Progress in vaccine development for infectious diseases—a Keystone Symposia report J Cable, BS Graham, RA Koup, RA Seder, K Karikó, N Pardi, DH Barouch, ... Annals of the New York Academy of Sciences 1524 (1), 65-86, 2023 | 1 | 2023 |
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu, VT Longping, ... Immunity 56 (3), 669-686. e7, 2023 | | 2023 |