The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the … S Kendrick, HJ Kang, MP Alam, MM Madathil, P Agrawal, V Gokhale, ... Journal of the American Chemical Society 136 (11), 4161-4171, 2014 | 283 | 2014 |
Relationship between structure, entropy and diffusivity in water and water-like liquids M Agarwal, M Singh, R Sharma, MP Alam, C Chakravarty Journal of Physical Chemistry B 114 (20), 6995-7001, 2010 | 97 | 2010 |
Cyanotryptophans as novel fluorescent probes for studying protein conformational changes and DNA–protein interaction P Talukder, S Chen, B Roy, P Yakovchuk, MM Spiering, MP Alam, ... Biochemistry 54 (51), 7457-7469, 2015 | 88 | 2015 |
Thermodynamic, diffusional, and structural anomalies in rigid-body water models M Agarwal, MP Alam, C Chakravarty The Journal of Physical Chemistry B 115 (21), 6935-6945, 2011 | 85 | 2011 |
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair R Shkhyan, B Van Handel, J Bogdanov, S Lee, Y Yu, M Scheinberg, ... Annals of the rheumatic diseases 77 (5), 760-769, 2018 | 59 | 2018 |
Interaction of Individual Structural Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA BR , Poulami Talukder, Hyun-Jin Kang, Shujian Sean Tsuen, Mohammad P. Alam ... J. Am. Chem. Soc., 2016 | 50 | 2016 |
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2 T Bilousova, C Elias, E Miyoshi, MP Alam, C Zhu, J Campagna, K Vadivel, ... Biochemical and biophysical research communications 499 (4), 751-757, 2018 | 31 | 2018 |
Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases MP Alam, OM Khdour, PM Arce, Y Chen, B Roy, WG Johnson, S Dey, ... Bioorganic & medicinal chemistry 22 (17), 4935-4947, 2014 | 25 | 2014 |
A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity MP Alam, T Bilousova, P Spilman, K Vadivel, D Bai, C Elias, D Evseenko, ... ACS Chemical Neuroscience, 2017 | 20 | 2017 |
C-O bond formation in a microfluidic reactor: high yield SNAr substitution of heteroaryl chlorides MP Alam, B Jagodzinska, J Campagna, P Spilman, V John Tetrahedron Letters 57 (19), 2059-2062, 2016 | 19 | 2016 |
DNA methylation reduces binding and cleavage by bleomycin B Roy, C Tang, MP Alam, SM Hecht Biochemistry 53 (38), 6103-6112, 2014 | 18 | 2014 |
A short DNA sequence confers strong bleomycin binding to hairpin DNAs C Tang, A Paul, MP Alam, B Roy, WD Wilson, SM Hecht Journal of the American Chemical Society 136 (39), 13715-13726, 2014 | 17 | 2014 |
Deformable nanovesicles synthesized through an adaptable microfluidic platform for enhanced localized transdermal drug delivery N Subbiah, J Campagna, P Spilman, MP Alam, S Sharma, A Hokugo, ... Journal of Drug Delivery 2017 (1), 4759839, 2017 | 16 | 2017 |
Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability A Chevalier, MP Alam, OM Khdour, M Schmierer, PM Arce, CD Cripe, ... Bioorganic & Medicinal Chemistry 24 (21), 5206-5220, 2016 | 12 | 2016 |
Therapeutic compounds S Hecht, O Khdour, M Alam, DEY Sriloy, C Yana, A Chevalier US Patent 10,364,227, 2019 | 7 | 2019 |
Synthesis of fused indolines by interrupted Fischer indolization in a microfluidic reactor ATH Duong, BJ Simmons, MP Alam, J Campagna, NK Garg, V John Tetrahedron letters 60 (3), 322-326, 2019 | 5 | 2019 |
3D-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids V John, J Campagna, T Bilousova, PR Spilman, PJ Heinzelman, A Hatami, ... US Patent 11,243,215, 2022 | | 2022 |
Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition MP Alam, V John, B Jagodzinska US Patent 11,077,108, 2021 | | 2021 |
GP130 modulators MP Alam, V John, P Spilman, K Vadivel US Patent 10,947,207, 2021 | | 2021 |
MOLDABLE NANOSCALE CARRIERS (DNVS) FOR ADMINISTRATION THROUGH THE BLOOD-BRAIN BARRIER, MUCCOUS AND SKIN V John, I Nishimura, N SUBBIAH, J CAMPAGNA, PR SPILMAN, MP ALAM | | 2020 |