| Amyloid-beta (Aβ) plaques promote seeding and spreading of alpha-synuclein and tau in a mouse model of Lewy body disorders with Aβ pathology F Bassil, HJ Brown, S Pattabhiraman, JE Iwasyk, CM Maghames, ... Neuron 105 (2), 260-275. e6, 2020 | 162 | 2020 |
| A microbiome-dependent gut–brain pathway regulates motivation for exercise L Dohnalová, P Lundgren, JRE Carty, N Goldstein, SL Wenski, ... Nature 612 (7941), 739-747, 2022 | 119 | 2022 |
| Silent allosteric modulation of mGluR5 maintains glutamate signaling while rescuing Alzheimer’s mouse phenotypes LT Haas, SV Salazar, LM Smith, HR Zhao, TO Cox, CS Herber, ... Cell reports 20 (1), 76-88, 2017 | 107 | 2017 |
| Serotonin reduction in post-acute sequelae of viral infection AC Wong, AS Devason, IC Umana, TO Cox, L Dohnalová, L Litichevskiy, ... Cell 186 (22), 4851-4867. e20, 2023 | 106 | 2023 |
| Liquid and hydrogel phases of PrPC linked to conformation shifts and triggered by Alzheimer’s amyloid-β oligomers MA Kostylev, MD Tuttle, S Lee, LE Klein, H Takahashi, TO Cox, ... Molecular cell 72 (3), 426-443. e12, 2018 | 100 | 2018 |
| Alzheimer's disease risk factor Pyk2 mediates amyloid-β-induced synaptic dysfunction and loss SV Salazar, TO Cox, S Lee, AH Brody, AS Chyung, LT Haas, ... Journal of Neuroscience 39 (4), 758-772, 2019 | 80 | 2019 |
| α-Synuclein modulates tau spreading in mouse brains F Bassil, ES Meymand, HJ Brown, H Xu, TO Cox, S Pattabhiraman, ... Journal of Experimental Medicine 218 (1), e20192193, 2020 | 57 | 2020 |
| Pyk2 signaling through Graf1 and RhoA GTPase is required for amyloid-β oligomer-triggered synapse loss S Lee, SV Salazar, TO Cox, SM Strittmatter Journal of Neuroscience 39 (10), 1910-1929, 2019 | 47 | 2019 |
| Metabolic control by the microbiome TO Cox, P Lundgren, K Nath, CA Thaiss Genome Medicine 14 (1), 80, 2022 | 42 | 2022 |
| Rescue of transgenic Alzheimer’s pathophysiology by polymeric cellular prion protein antagonists EC Gunther, LM Smith, MA Kostylev, TO Cox, AC Kaufman, S Lee, ... Cell reports 26 (1), 145-158. e8, 2019 | 42 | 2019 |
| NAD precursors cycle between host tissues and the gut microbiome K Chellappa, MR McReynolds, W Lu, X Zeng, M Makarov, F Hayat, ... Cell metabolism 34 (12), 1947-1959. e5, 2022 | 41 | 2022 |
| Anti‐PrPC antibody rescues cognition and synapses in transgenic alzheimer mice TO Cox, EC Gunther, AH Brody, MT Chiasseu, A Stoner, LM Smith, ... Annals of Clinical and Translational Neurology 6 (3), 554-574, 2019 | 28 | 2019 |
| A subpopulation of lipogenic brown adipocytes drives thermogenic memory P Lundgren, PV Sharma, L Dohnalová, K Coleman, GT Uhr, S Kircher, ... Nature Metabolism 5 (10), 1691-1705, 2023 | 6 | 2023 |
| Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice L Litichevskiy, M Considine, J Gill, V Shandar, TO Cox, HC Descamps, ... bioRxiv, 2023.11. 28.568137, 2023 | | 2023 |
