Promotion of tumor invasion by tumor-associated macrophages: the role of CSF-1-activated phosphatidylinositol 3 kinase and Src family kinase motility signaling AR Dwyer, EL Greenland, FJ Pixley Cancers 9 (6), 68, 2017 | 77 | 2017 |
Phosphorylated progesterone receptor isoforms mediate opposing stem cell and proliferative breast cancer cell fates TH Truong, AR Dwyer, CH Diep, H Hu, KM Hagen, CA Lange Endocrinology 160 (2), 430-446, 2019 | 52 | 2019 |
Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer C Perez Kerkvliet, AR Dwyer, CH Diep, RH Oakley, C Liddle, ... Breast Cancer Research 22, 1-23, 2020 | 47 | 2020 |
CSF-1R signaling in health and disease: a focus on the mammary gland AR Sullivan, FJ Pixley Journal of mammary gland biology and neoplasia 19, 149-159, 2014 | 40 | 2014 |
High-throughput imaging assay for drug screening of 3D prostate cancer organoids N Choo, S Ramm, J Luu, JM Winter, LA Selth, AR Dwyer, M Frydenberg, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (9), 1107-1124, 2021 | 38 | 2021 |
90 YEARS OF PROGESTERONE: Steroid receptors as MAPK signaling sensors in breast cancer: let the fates decide AR Dwyer, TH Truong, JH Ostrander, CA Lange Journal of molecular endocrinology 65 (1), T35-T48, 2020 | 37 | 2020 |
A three-dimensional co-culture system to investigate macrophage-dependent tumor cell invasion AR Dwyer, LG Ellies, AL Holme, FJ Pixley Journal of biological methods 3 (3), 2016 | 32 | 2016 |
Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer AR Dwyer, TH Truong, CP Kerkvliet, KV Paul, P Kabos, CA Sartorius, ... British Journal of Cancer 124 (1), 217-227, 2021 | 27 | 2021 |
Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration AR Dwyer, KA Mouchemore, JH Steer, AJ Sunderland, NG Sampaio, ... Journal of Leucocyte Biology 100 (1), 163-175, 2016 | 27 | 2016 |
Inhibition of the SRC kinase HCK impairs STAT3-dependent gastric tumor growth in mice AR Poh, AR Dwyer, MF Eissmann, AL Chand, D Baloyan, L Boon, ... Cancer immunology research 8 (4), 428-435, 2020 | 25 | 2020 |
Breast tumor kinase (Brk/PTK6) mediates advanced cancer phenotypes via SH2-domain dependent activation of RhoA and aryl hydrocarbon receptor (AhR) signaling AR Dwyer, CP Kerkvliet, RI Krutilina, HC Playa, DN Parke, WA Thomas, ... Molecular Cancer Research 19 (2), 329-345, 2021 | 15 | 2021 |
UV Irradiation of skin enhances glycolytic flux and reduces migration capabilities in bone marrow–differentiated dendritic cells TA McGonigle, KN Keane, S Ghaly, KW Carter, D Anderson, NM Scott, ... The American Journal of Pathology 187 (9), 2046-2059, 2017 | 12 | 2017 |
Glucocorticoid receptors drive breast cancer cell migration and metabolic reprogramming via PDK4 AR Dwyer, C Perez Kerkvliet, TH Truong, KM Hagen, RI Krutilina, ... Endocrinology 164 (7), bqad083, 2023 | 10 | 2023 |
Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer TE Hickey, AR Dwyer, WD Tilley British Journal of Cancer 125 (12), 1599-1601, 2021 | 8 | 2021 |
PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo TA McGonigle, AR Dwyer, EL Greenland, NM Scott, KN Keane, ... Experimental hematology 56, 64-68, 2017 | 7 | 2017 |
Reticulon-1 and reduced migration toward chemoattractants by macrophages differentiated from the bone marrow of ultraviolet-irradiated and ultraviolet-chimeric mice TA McGonigle, AR Dwyer, EL Greenland, NM Scott, KW Carter, KN Keane, ... The Journal of Immunology 200 (1), 260-270, 2018 | 6 | 2018 |
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced … C Palmieri, H Linden, SN Birrell, S Wheelwright, E Lim, LS Schwartzberg, ... The Lancet Oncology 25 (3), 317-325, 2024 | 4 | 2024 |
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity S Prekovic, T Chalkiadakis, M Roest, D Roden, C Lutz, K Schuurman, ... EMBO Molecular Medicine 15 (12), e17737, 2023 | 4 | 2023 |
Selective inhibition of CDK9 in triple negative breast cancer EH Mustafa, G Laven-Law, Z Kikhtyak, V Nguyen, S Ali, AA Pace, R Iggo, ... Oncogene 43 (3), 202-215, 2024 | 2 | 2024 |
The pure progesterone receptor (PR) antagonist onapristone enhances the anti-proliferative effects of CDK4/6 inhibitors in preclinical in-vitro breast cancer models D Lala, T Haque, H Feinman, J Wu, Y Wang, A Dwyer, T Truong, C Lange Cancer Research 79 (4), 2019 | 2 | 2019 |