Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα BH Hayes, RK Tsai, LJ Dooling, S Kadu, JY Lee, D Pantano, ... Journal of cell science 133 (5), jcs237800, 2020 | 51 | 2020 |
Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses LJ Dooling, JC Andrechak, BH Hayes, S Kadu, W Zhang, R Pan, ... Nature Biomedical Engineering 7 (9), 1081-1096, 2023 | 26 | 2023 |
Sequential exposure to IL21 and IL15 during human natural killer cell expansion optimizes yield and function C Zhang, S Kadu, Y Xiao, O Johnson, A Kelly, RS O'Connor, M Lai, ... Cancer immunology research 11 (11), 1524-1537, 2023 | 8 | 2023 |
Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy Y Tang, W Liu, S Kadu, O Johnson, ZS Hasanali, A Kelly, A Shestov, ... Blood 143 (2), 139-151, 2024 | 6 | 2024 |
Cooperative phagocytosis underlies macrophage immunotherapy of solid tumours and initiates a broad anti-tumour IgG response JC Andrechak, LJ Dooling, BH Hayes, S Kadu, W Zhang, R Pan, ... biorxiv, 2022.01. 01.474150, 2022 | 4 | 2022 |
Solid Tumor Cures by Complete Disruption of the CD47: SIRPα Macrophage Checkpoint, Tumor Opsonization, and ‘Phagocytic Feedback’ LJ Dooling, JC Andrechak, BH Hayes, S Kadu, R Pan, MP Tobin, ... Biophysical Journal 120 (3), 89a, 2021 | 1 | 2021 |
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice ZS Hasanali, AL Garfall, L Burzenski, LD Shultz, Y Tang, S Kadu, ... JCI insight 9 (10), 2024 | | 2024 |
Macrophages Aggregate and Cooperate to Phagocytose Cohesive Tumor Cell Targets in Engineered Immuno-Tumoroids and Solid Tumors LJ Dooling, JC Andrechak, BH Hayes, S Kadu, DE Discher 2022 AIChE Annual Meeting, 2022 | | 2022 |
Macrophages Cooperatively Phagocytose Solid Tumors in Macrophage Immunotherapy and Initiate an Anti-Tumor Antibody Feedback Loop JC Andrechak, LJ Dooling, S Kadu, W Zhang, JY Lee, BH Hayes, R Pan, ... MOLECULAR THERAPY 30 (4), 508-508, 2022 | | 2022 |
Macrophage Checkpoint Blockade: From Cell Therapy and CRISPR Models to Acquired Immunity LJ Dooling, JC Andrechak, BH Hayes, S Kadu, DE Discher 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Adaptive Immune Responses Against Solid Tumors Mediated by Macrophage Checkpoint Blockade JC Andrechak, LJ Dooling, BH Hayes, JY Lee, S Kadu, R Pan, ... MOLECULAR THERAPY 28 (4), 153-153, 2020 | | 2020 |
Mouse Melanoma B16 Tumors are Soft and Engulfable when Targeted in Combination with Macrophage Checkpoint Blockade LJ Dooling, BH Hayes, JC Andrechak, S Kadu, DE Discher Biophysical Journal 118 (3), 155a-156a, 2020 | | 2020 |
Sequential Exposure to Interleukin-21 and Interleukin-15 During Human Natural Killer Cell Expansion Optimizes Yield and Function C Zhang, S Kadu, Y Xiao, O Johnson, A Kelly, RS O’Connor, M Lai, ... | | |
Macrophages eat more after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα BH Hayes, RK Tsai, LJ Dooling, S Kadu, JY Lee, D Pantano, ... MACROPHAGES & CHROMOSOMAL INSTABILITY, 1, 0 | | |