Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction S Ellouze, S Augustin, A Bouaita, C Bonnet, M Simonutti, V Forster, ... The American Journal of Human Genetics 83 (3), 373-387, 2008 | 247 | 2008 |
Complement factor H inhibits CD47-mediated resolution of inflammation B Calippe, S Augustin, F Beguier, H Charles-Messance, L Poupel, ... Immunity 46 (2), 261-272, 2017 | 143 | 2017 |
The optimized allotopic expression of ND1 or ND4 genes restores respiratory chain complex I activity in fibroblasts harboring mutations in these genes C Bonnet, S Augustin, S Ellouze, P Bénit, A Bouaita, P Rustin, JA Sahel, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (10), 1707-1717, 2008 | 132 | 2008 |
Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits C Bonnet, V Kaltimbacher, S Ellouze, S Augustin, P Bénit, V Forster, ... Rejuvenation research 10 (2), 127-144, 2007 | 101 | 2007 |
Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss H Cwerman-Thibault, S Augustin, C Lechauve, J Ayache, S Ellouze, ... Molecular Therapy Methods & Clinical Development 2, 2015 | 78 | 2015 |
Subretinal mononuclear phagocytes induce cone segment loss via IL-1β CM Eandi, H Charles Messance, S Augustin, E Dominguez, S Lavalette, ... Elife 5, e16490, 2016 | 77 | 2016 |
Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity C Lechauve, S Augustin, H Cwerman-Thibault, A Bouaita, V Forster, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (12), 2261-2273, 2012 | 76 | 2012 |
Gene therapy for mitochondrial diseases: Leber Hereditary Optic Neuropathy as the first candidate for a clinical trial H Cwerman-Thibault, S Augustin, S Ellouze, JA Sahel, M Corral-Debrinski Comptes Rendus. Biologies 337 (3), 193-206, 2014 | 61 | 2014 |
The 10q26 risk haplotype of age-related macular degeneration aggravates subretinal inflammation by impairing monocyte elimination F Beguier, M Housset, C Roubeix, S Augustin, Y Zagar, C Nous, T Mathis, ... Immunity 53 (2), 429-441. e8, 2020 | 60 | 2020 |
Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX 2 expression via TNF‐α T Mathis, M Housset, C Eandi, F Beguier, S Touhami, S Reichman, ... Aging Cell 16 (1), 173-182, 2017 | 50 | 2017 |
ANGPTL4–αvβ3 interaction counteracts hypoxia‐induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2 E Gomez Perdiguero, A Liabotis‐Fontugne, M Durand, C Faye, ... The Journal of Pathology 240 (4), 461-471, 2016 | 50 | 2016 |
In vivo observation of the locomotion of microglial cells in the retina M Paques, M Simonutti, S Augustin, O Goupille, B El Mathari, JA Sahel Glia 58 (14), 1663-1668, 2010 | 42 | 2010 |
Foxg1-Cre mediated Lrp2 inactivation in the developing mouse neural retina, ciliary and retinal pigment epithelia models congenital high myopia O Cases, A Joseph, A Obry, MD Santin, S Ben-Yacoub, M Pâques, ... PloS one 10 (6), e0129518, 2015 | 41 | 2015 |
Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy A Bouaita, S Augustin, C Lechauve, H Cwerman-Thibault, P Bénit, ... Brain 135 (1), 35-52, 2012 | 40 | 2012 |
Neuroglobin involvement in visual pathways through the optic nerve C Lechauve, S Augustin, D Roussel, JA Sahel, M Corral-Debrinski Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (9), 1772-1778, 2013 | 39 | 2013 |
IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis H Charles-Messance, G Blot, A Couturier, L Vignaud, S Touhami, ... Journal of neuroinflammation 17, 1-12, 2020 | 38 | 2020 |
Neuroglobin can prevent or reverse glaucomatous progression in DBA/2J mice H Cwerman-Thibault, C Lechauve, S Augustin, D Roussel, É Reboussin, ... Molecular therapy Methods & clinical development 5, 200-220, 2017 | 38 | 2017 |
Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells S Augustin, M Berard, S Kellaf, N Peyri, F Fauvel-Lafeve, C Legrand, ... Anticancer research 29 (4), 1335-1343, 2009 | 36 | 2009 |
Neuroglobin gene therapy prevents optic atrophy and preserves durably visual function in Harlequin mice C Lechauve, S Augustin, H Cwerman-Thibault, É Reboussin, D Roussel, ... Molecular Therapy 22 (6), 1096-1109, 2014 | 34 | 2014 |
Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation S Touhami, F Beguier, S Augustin, H Charles-Messance, L Vignaud, ... Journal of neuroinflammation 15, 1-11, 2018 | 30 | 2018 |