Improving reporting standards for polygenic scores in risk prediction studies H Wand, SA Lambert, C Tamburro, MA Iacocca, JW O’Sullivan, C Sillari, ... Nature 591 (7849), 211-219, 2021 | 344 | 2021 |
Polygenic versus monogenic causes of hypercholesterolemia ascertained clinically J Wang, JS Dron, MR Ban, JF Robinson, AD McIntyre, M Alazzam, ... Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2439-2445, 2016 | 217 | 2016 |
Severe hypertriglyceridemia is primarily polygenic JS Dron, J Wang, H Cao, AD McIntyre, MA Iacocca, JR Menard, ... Journal of clinical lipidology 13 (1), 80-88, 2019 | 189 | 2019 |
Genetics of hypertriglyceridemia JS Dron, RA Hegele Frontiers in endocrinology 11, 455, 2020 | 161 | 2020 |
Genetics of triglycerides and the risk of atherosclerosis JS Dron, RA Hegele Current atherosclerosis reports 19, 1-10, 2017 | 117 | 2017 |
Targeted next generation sequencing as a tool for precision medicine M Gulilat, T Lamb, WA Teft, J Wang, JS Dron, JF Robinson, RG Tirona, ... BMC medical genomics 12, 1-17, 2019 | 90 | 2019 |
PCSK9: regulation and target for drug development for dyslipidemia AC Burke, JS Dron, RA Hegele, MW Huff Annual review of pharmacology and toxicology 57 (1), 223-244, 2017 | 87 | 2017 |
Complexity of mechanisms among human proprotein convertase subtilisin–kexin type 9 variants JS Dron, RA Hegele Current opinion in lipidology 28 (2), 161-169, 2017 | 81 | 2017 |
Use of next-generation sequencing to detect LDLR gene copy number variation in familial hypercholesterolemia MA Iacocca, J Wang, JS Dron, JF Robinson, AD McIntyre, H Cao, ... Journal of lipid research 58 (11), 2202-2209, 2017 | 79 | 2017 |
Erratum to: Genetics of Lipid and Lipoprotein Disorders and Traits JS Dron, RA Hegele Current Genetic Medicine Reports 5, 115-115, 2017 | 69* | 2017 |
Polygenic determinants in extremes of high-density lipoprotein cholesterol JS Dron, J Wang, C Low-Kam, SA Khetarpal, JF Robinson, AD McIntyre, ... Journal of lipid research 58 (11), 2162-2170, 2017 | 67 | 2017 |
Six years’ experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias JS Dron, J Wang, AD McIntyre, MA Iacocca, JF Robinson, MR Ban, H Cao, ... BMC Medical Genomics 13, 1-15, 2020 | 64 | 2020 |
Polygenic influences on dyslipidemias JS Dron, RA Hegele Current Opinion in Lipidology, 2018 | 62 | 2018 |
The evolution of genetic-based risk scores for lipids and cardiovascular disease JS Dron, RA Hegele Current opinion in lipidology 30 (2), 71-81, 2019 | 61 | 2019 |
Whole-gene duplication of PCSK9 as a novel genetic mechanism for severe familial hypercholesterolemia MA Iacocca, J Wang, S Sarkar, JS Dron, T Lagace, AD McIntyre, P Lau, ... Canadian Journal of Cardiology 34 (10), 1316-1324, 2018 | 50 | 2018 |
Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia JS Dron, AA Dilliott, A Lawson, AD McIntyre, BD Davis, J Wang, H Cao, ... Arteriosclerosis, Thrombosis, and Vascular Biology 40 (8), 1935-1941, 2020 | 44 | 2020 |
The polygenic nature of mild-to-moderate hypertriglyceridemia JS Dron, J Wang, AD McIntyre, H Cao, RA Hegele Journal of clinical lipidology 14 (1), 28-34. e2, 2020 | 41 | 2020 |
Design and user experience testing of a polygenic score report: a qualitative study of prospective users DG Brockman, L Petronio, JS Dron, BC Kwon, T Vosburg, L Nip, A Tang, ... BMC Medical Genomics 14, 1-20, 2021 | 39 | 2021 |
Targeted sequencing reveals expanded genetic diversity of human transfer RNAs MD Berg, DJ Giguere, JS Dron, JT Lant, J Genereaux, C Liao, J Wang, ... RNA biology 16 (11), 1574-1585, 2019 | 32 | 2019 |
Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia JS Dron, J Wang, AJ Berberich, MA Iacocca, H Cao, P Yang, J Knoll, ... Journal of Lipid Research 59 (8), 1529-1535, 2018 | 32 | 2018 |