Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, ... Journal of Experimental Medicine 215 (6), 1729-1747, 2018 | 145 | 2018 |
Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis S Asada, S Goyama, D Inoue, S Shikata, R Takeda, T Fukushima, ... Nature communications 9 (1), 2733, 2018 | 114 | 2018 |
Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway T Fujino, S Goyama, Y Sugiura, D Inoue, S Asada, S Yamasaki, ... Nature communications 12 (1), 1826, 2021 | 73 | 2021 |
Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia HJ Uckelmann, EL Haarer, R Takeda, EM Wong, C Hatton, C Marinaccio, ... Cancer discovery 13 (3), 746-765, 2023 | 41 | 2023 |
Discrimination of dormant and active hematopoietic stem cells by G0 marker reveals dormancy regulation by cytoplasmic calcium T Fukushima, Y Tanaka, FK Hamey, CH Chang, T Oki, S Asada, ... Cell Reports 29 (12), 4144-4158. e7, 2019 | 37 | 2019 |
A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells K Yamamoto, S Goyama, S Asada, T Fujino, T Yonezawa, N Sato, ... Cell reports 36 (8), 2021 | 19 | 2021 |
HLA-DRB1 mismatch is associated with a decreased relapse in adult acute myeloid leukemia after single-unit myeloablative cord blood transplantation T Konuma, S Kato, H Ishii, R Takeda, M Oiwa-Monna, A Tojo, ... Annals of Hematology 94, 1233-1235, 2015 | 18 | 2015 |
MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Y Hayashi, KC Kawabata, Y Tanaka, Y Uehara, Y Mabuchi, K Murakami, ... Cell reports 39 (6), 2022 | 17 | 2022 |
Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors Y Tanaka, R Takeda, T Fukushima, K Mikami, S Tsuchiya, M Tamura, ... Nature Communications 13 (1), 271, 2022 | 17 | 2022 |
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia T Isobe, M Takagi, A Sato-Otsubo, A Nishimura, G Nagae, C Yamagishi, ... Nature communications 13 (1), 4501, 2022 | 15 | 2022 |
HHEX promotes myeloid transformation in cooperation with mutant ASXL1 R Takeda, S Asada, SJ Park, A Yokoyama, HJ Becker, A Kanai, ... Blood, The Journal of the American Society of Hematology 136 (14), 1670-1684, 2020 | 15 | 2020 |
High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis KC Kawabata, Y Hayashi, D Inoue, H Meguro, H Sakurai, T Fukuyama, ... Leukemia 32 (2), 419-428, 2018 | 10 | 2018 |
The first case of elderly TCF3-HLF-positive B-cell acute lymphoblastic leukemia R Takeda, K Yokoyama, M Ogawa, T Kawamata, T Fukuyama, K Kondoh, ... Leukemia & Lymphoma 60 (11), 2821-2824, 2019 | 7 | 2019 |
Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With MLL Gene Amplification: A Case Report and Literature … R Takeda, K Yokoyama, T Fukuyama, T Kawamata, M Ito, N Yusa, ... Frontiers in Oncology 12, 799982, 2022 | 5 | 2022 |
Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun 12: 1826 T Fujino, S Goyama, Y Sugiura, D Inoue, S Asada, S Yamasaki, ... | 5 | 2021 |
Immunophenotypic analysis of cerebrospinal fluid reveals concurrent development of ATL in the CNS of a HAM/TSP patient R Takeda, T Ishigaki, N Ohno, K Yokoyama, T Kawamata, T Fukuyama, ... International Journal of Hematology 111, 891-896, 2020 | 3 | 2020 |
Nested polymerase chain reaction with specific primers for mucorales in the serum of patients with hematological malignancies M Hirano, Y Ota, T Koibuchi, T Takei, R Takeda, T Kawamata, ... Japanese Journal of Infectious Diseases 72 (3), 196-198, 2019 | 2 | 2019 |
An Unusually Short Latent Period of Therapy‐Related Myeloid Neoplasm Harboring a Rare MLL‐EP300 Rearrangement: Case Report and Literature Review R Takeda, K Yokoyama, S Kobayashi, T Kawamata, S Nakamura, ... Case Reports in Hematology 2019 (1), 4532434, 2019 | 2 | 2019 |
3011–MUTANT ASXL1 INDUCES EXPANSION OF HEMATOPOIETIC STEM CELLS THROUGH ACTIVATION OF AKT/MTOR PATHWAY T Fujino, S Goyama, Y Sugiura, D Inoue, S Asada, S Yamasaki, ... Experimental Hematology 88, S41, 2020 | 1 | 2020 |
Mutant ASXL1 collaborates with HHEX to promote myeloid leukemogenesis S Asada, R Takeda, D Inoue, S Goyama, T Kitamura Cancer Research 79 (13_Supplement), 4643-4643, 2019 | 1 | 2019 |