Differential roles of M1 and M2 microglia in neurodegenerative diseases Y Tang, W Le Molecular Neurobiology 53 (2), 1181-1194, 2016 | 2121 | 2016 |
MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis X Zhang, S Chen, L Song, Y Tang, Y Shen, L Jia, W Le Autophagy 10 (4), 588-602, 2014 | 261 | 2014 |
Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson’s disease Y Tang, T Li, J Li, J Yang, H Liu, XJ Zhang, W Le Cell Death Differ 21 (3), 369-380, 2014 | 232 | 2014 |
miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression D Yang, T Li, Y Wang, Y Tang, H Cui, Y Tang, X Zhang, D Chen, N Shen, ... Journal of cell science 125 (7), 1673-1682, 2012 | 184 | 2012 |
Direct reprogramming rather than iPSC-based reprogramming maintains aging hallmarks in human motor neurons Y Tang, ML Liu, T Zang, CL Zhang Frontiers in molecular neuroscience 10, 359, 2017 | 157 | 2017 |
Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease L Li, S Zhang, X Zhang, T Li, Y Tang, H Liu, W Yang, W Le Current Alzheimer Research 10 (4), 433-441, 2013 | 146 | 2013 |
Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons Z Wang, D Yang, X Zhang, T Li, J Li, Y Tang, W Le PloS one 6 (4), e19229, 2011 | 141 | 2011 |
Protective Microglia and Their Regulation in Parkinson’s Disease W Le, J Wu, Y Tang Front Mol Neurosci 9 (89), 2016 | 129 | 2016 |
Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation T Li, D Yang, J Li, Y Tang, J Yang, W Le Molecular neurobiology 51, 142-154, 2015 | 100 | 2015 |
Adaptive changes in autophagy after UPS impairment in Parkinson's disease Y Shen, Y Tang, X Zhang, K HuANG, W Le Acta Pharmacologica Sinica 34 (5), 667-673, 2013 | 65 | 2013 |
Early pathogenic event of Alzheimer’s disease documented in iPSCs from patients with PSEN1 mutations J Yang, H Zhao, Y Ma, G Shi, J Song, Y Tang, S Li, T Li, N Liu, F Tang, ... Oncotarget 8 (5), 7900, 2017 | 61 | 2017 |
Gene4Denovo: an integrated database and analytic platform for de novo mutations in humans G Zhao, K Li, B Li, Z Wang, Z Fang, X Wang, Y Zhang, T Luo, Q Zhou, ... Nucleic acids research 48 (D1), D913-D926, 2020 | 59 | 2020 |
Valproic Acid Reduces Neuritic Plaque Formation and Improves Learning Deficits in APPSwe/PS1A246E Transgenic Mice via Preventing the Prenatal Hypoxia … Z Wang, XJ Zhang, T Li, J Li, Y Tang, W Le CNS neuroscience & therapeutics 20 (3), 209-217, 2014 | 53 | 2014 |
Disease modeling with human neurons reveals LMNB1 dysregulation underlying DYT1 dystonia B Ding, Y Tang, S Ma, M Akter, ML Liu, T Zang, CL Zhang Journal of Neuroscience 41 (9), 2024-2038, 2021 | 50 | 2021 |
Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells J Yang, Y Tang, H Liu, F Guo, J Ni, W Le BMC biology 12, 1-17, 2014 | 48 | 2014 |
Gender segregation in gene expression and vulnerability to oxidative stress induced injury in ventral mesencephalic cultures of dopamine neurons Q Tao, X Fan, T Li, Y Tang, D Yang, W Le Journal of neuroscience research 90 (1), 167-178, 2012 | 39 | 2012 |
Microglial polarization in the pathogenesis and therapeutics of neurodegenerative diseases Y Tang Frontiers in aging neuroscience 10, 154, 2018 | 31 | 2018 |
Human superoxide dismutase 1 overexpression in motor neurons of Caenorhabditis elegans causes axon guidance defect and neurodegeneration J Li, T Li, X Zhang, Y Tang, J Yang, W Le Neurobiology of aging 35 (4), 837-846, 2014 | 31 | 2014 |
Allele-specific genome targeting in the development of precision medicine J Wu, B Tang, Y Tang Theranostics 10 (7), 3118-3137, 2020 | 29 | 2020 |
SOX4-mediated repression of specific tRNAs inhibits proliferation of human glioblastoma cells J Yang, DK Smith, H Ni, K Wu, D Huang, S Pan, AA Sathe, Y Tang, ML Liu, ... Proceedings of the National Academy of Sciences 117 (11), 5782-5790, 2020 | 26 | 2020 |