Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis MF Bezerra, AS Lima, MR Piqué-Borràs, DR Silveira, JL Coelho-Silva, ... Blood, The Journal of the American Society of Hematology 135 (11), 870-875, 2020 | 76 | 2020 |
High levels of proinflammatory cytokines IL-6 and IL-8 are associated with a poor clinical outcome in sickle cell anemia IF Domingos, DA Pereira-Martins, MJVC Sobreira, RTD Oliveira, ... Annals of Hematology 99, 947-953, 2020 | 40 | 2020 |
Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma RTC Julieta Panero, Raquel M Alves-Paiva, Alejandro Roisman, Barbara A ... American Journal of Hematology 91 (5), 481-485, 2016 | 36 | 2016 |
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia A Erdem, S Marin, DA Pereira-Martins, R Cortés, A Cunningham, ... Nature Communications 13 (1), 1105, 2022 | 34 | 2022 |
Dietary methionine starvation impairs acute myeloid leukemia progression A Cunningham, A Erdem, I Alshamleh, M Geugien, M Pruis, ... Blood, The Journal of the American Society of Hematology 140 (19), 2037-2052, 2022 | 32 | 2022 |
Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia AR Lucena-Araujo, JL Coelho-Silva, DA Pereira-Martins, DR Silveira, ... Blood, The Journal of the American Society of Hematology 134 (12), 951-959, 2019 | 30 | 2019 |
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability A Erdem, S Marin, DA Pereira-Martins, M Geugien, A Cunningham, ... Nature Communications 13 (1), 2013, 2022 | 29 | 2022 |
PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia K Lima, JL Coelho-Silva, GS Kinker, DA Pereira-Martins, F Traina, ... Cancer Genetics 233, 56-66, 2019 | 22 | 2019 |
Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia DRA Silveira, L Quek, IS Santos, A Corby, JL Coelho-Silva, ... Blood advances 4 (10), 2339-2350, 2020 | 18 | 2020 |
M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism I Weinhäuser, DA Pereira-Martins, LY Almeida, JR Hilberink, DRA Silveira, ... Science Advances 9 (15), eadf8522, 2023 | 16 | 2023 |
Influence of UGT1A1 promoter polymorphism, α-thalassemia and βs haplotype in bilirubin levels and cholelithiasis in a large sickle cell anemia cohort JVGF Batista, GS Arcanjo, THC Batista, MJ Sobreira, RM Santana, ... Annals of Hematology 100, 903-911, 2021 | 16 | 2021 |
Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia AR Lucena-Araujo, DA Pereira-Martins, LC Koury, PL Franca-Neto, ... Blood advances 1 (21), 1807-1814, 2017 | 14 | 2017 |
The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy K Lima, DA Pereira-Martins, LBL de Miranda, JL Coelho-Silva, ... Blood cancer journal 12 (11), 151, 2022 | 12 | 2022 |
Evaluation of oxidative stress-related genetic variants for predicting stroke in patients with sickle cell anemia IF Domingos, DA Pereira-Martins, RL Borges-Medeiros, DA Falcao, ... Journal of the Neurological Sciences 414, 116839, 2020 | 12 | 2020 |
A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings? DRA Silveira, JL Coelho-Silva, WF Silva, G Vallance, DA Pereira-Martins, ... Leukemia & Lymphoma 62 (1), 147-157, 2021 | 11 | 2021 |
Reduced SLIT2 is associated with increased cell proliferation and arsenic trioxide resistance in acute promyelocytic leukemia I Weinhäuser, DA Pereira-Martins, C Ortiz, DR Silveira, LAA Simoes, ... Cancers 12 (11), 3134, 2020 | 11 | 2020 |
The combination of gefitinib with ATRA and ATO induces myeloid differentiation in acute promyelocytic leukemia resistant cells LY Almeida, DA Pereira-Martins, I Weinhäuser, C Ortiz, LA Cândido, ... Frontiers in oncology 11, 686445, 2021 | 10 | 2021 |
MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model DA Pereira-Martins, I Weinhäuser, JL Coelho-Silva, PL França-Neto, ... Cell death & disease 12 (4), 371, 2021 | 9 | 2021 |
Alpha thalassemia, but not βS-globin haplotypes, influence sickle cell anemia clinical outcome in a large, single-center Brazilian cohort BLD Hatzlhofer, DA Pereira-Martins, I de Farias Domingos, GS Arcanjo, ... Annals of Hematology 100, 921-931, 2021 | 9 | 2021 |
The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia A Cunningham, LL Oudejans, M Geugien, DA Pereira-Martins, ... Blood advances 8 (1), 56-69, 2024 | 8 | 2024 |