| Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4) WT Choi, S Duggineni, Y Xu, Z Huang, J An Journal of medicinal chemistry 55 (3), 977-994, 2012 | 123 | 2012 |
| Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction W Tian, X Han, M Yan, Y Xu, S Duggineni, N Lin, G Luo, YM Li, X Han, ... Biochemistry 51 (2), 724-731, 2012 | 103 | 2012 |
| Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis WT Choi, Y Yang, Y Xu, J An Current topics in medicinal chemistry 14 (13), 1574-1589, 2014 | 60 | 2014 |
| Design and synthesis of potent bivalent peptide agonists targeting the EphA2 receptor S Duggineni, S Mitra, I Lamberto, X Han, Y Xu, J An, EB Pasquale, ... ACS medicinal chemistry letters 4 (3), 344-348, 2013 | 43 | 2013 |
| A synthetic bivalent ligand of CXCR4 inhibits HIV infection Y Xu, S Duggineni, S Espitia, DD Richman, J An, Z Huang Biochemical and biophysical research communications 435 (4), 646-650, 2013 | 38 | 2013 |
| The chemical biology of apoptosis: revisited after 17 years S Yang, Y Mao, H Zhang, Y Xu, J An, Z Huang European Journal of Medicinal Chemistry 177, 63-75, 2019 | 32 | 2019 |
| Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4 S Duggineni, S Mitra, R Noberini, X Han, N Lin, Y Xu, W Tian, J An, ... Biochemical pharmacology 85 (4), 507-513, 2013 | 28 | 2013 |
| Development of a Novel Fluorescence Polarization–Based Assay for Studying the β-Catenin/Tcf4 Interaction W Tian, Y Xu, X Han, S Duggineni, X Han, Z Huang, J An Journal of Biomolecular Screening 17 (4), 530-534, 2012 | 26 | 2012 |
| A new class of α-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities J Wang, B Liang, Y Chen, JFW Chan, S Yuan, H Ye, L Nie, J Zhou, Y Wu, ... European journal of medicinal chemistry 215, 113267, 2021 | 15 | 2021 |
| Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity X Han, Y Xu, Y Yang, J Xi, W Tian, S Duggineni, Z Huang, J An PloS one 8 (11), e80183, 2013 | 15 | 2013 |
| Virtual screening, biological evaluation, and 3D-QSAR studies of new HIV-1 entry inhibitors that function via the CD4 primary receptor C Zhang, H Zhang, LS Huang, S Zhu, Y Xu, XQ Zhang, RT Schooley, ... Molecules 23 (11), 3036, 2018 | 13 | 2018 |
| Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1α probed by novel N-methylated synthetically and modularly … CZ Dong, S Tian, WT Choi, S Kumar, D Liu, Y Xu, X Han, Z Huang, J An Biochemistry 51 (30), 5951-5957, 2012 | 13 | 2012 |
| Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration JP Lee, R Zhang, M Yan, S Duggineni, DR Wakeman, WL Niles, Y Feng, ... Proceedings of the National Academy of Sciences 117 (49), 31177-31188, 2020 | 12 | 2020 |
| Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists X Fang, Q Meng, H Zhang, B Liang, S Zhu, J Wang, C Zhang, LS Huang, ... European Journal of Medicinal Chemistry 200, 112410, 2020 | 11 | 2020 |
| Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities H Zhang, X Fang, Q Meng, Y Mao, Y Xu, T Fan, J An, Z Huang European Journal of Medicinal Chemistry 157, 380-396, 2018 | 11 | 2018 |
| High affinity CXCR4 inhibitors generated by linking low affinity peptides C Zhang, LS Huang, R Zhu, Q Meng, S Zhu, Y Xu, H Zhang, X Fang, ... European journal of medicinal chemistry 172, 174-185, 2019 | 10 | 2019 |
| Discovery and computational analyses of novel small molecule Zika virus inhibitors S Zhu, C Zhang, LS Huang, XQ Zhang, Y Xu, X Fang, J Zhou, M Wu, ... Molecules 24 (8), 1465, 2019 | 10 | 2019 |
| Novel bivalent and D-peptide ligands of CXCR4 mobilize hematopoietic progenitor cells to the blood in C3H/HeJ mice Y Mao, Q Meng, P Song, S Zhu, Y Xu, EY Snyder, J An, Z Huang Cell Transplantation 27 (8), 1249-1255, 2018 | 8 | 2018 |
| A novel dimeric CXCR4 antagonist synergizes with chemotherapy in acute myeloid leukaemia by mobilizing leukaemic cells from their associated bone marrow niches. Y Huang, Z Huang, J An, Y Xu British Journal of Haematology 187 (1), 2019 | 7 | 2019 |
| A chemical strategy for the degradation of the main protease of SARS-CoV-2 in cells X Sang, J Wang, J Zhou, Y Xu, J An, A Warshel, Z Huang Journal of the American Chemical Society 145 (50), 27248-27253, 2023 | 6 | 2023 |
