Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis CJ Weston, EL Shepherd, LC Claridge, P Rantakari, SM Curbishley, ... The Journal of clinical investigation 125 (2), 501-520, 2015 | 223 | 2015 |
Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience RH Bhogal, J Hodson, DC Bartlett, CJ Weston, SM Curbishley, ... PloS one 6 (3), e18222, 2011 | 181 | 2011 |
Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells B Eksteen, JR Mora, EL Haughton, NC Henderson, L Lee–Turner, ... Gastroenterology 137 (1), 320-329, 2009 | 146 | 2009 |
Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver AP Holt, EL Haughton, PF Lalor, A Filer, CD Buckley, DH Adams Gastroenterology 136 (2), 705-714, 2009 | 144 | 2009 |
Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro EL Haughton, SJ Tucker, CJ Marek, E Durward, V Leel, Z Bascal, ... Gastroenterology 131 (1), 194-209, 2006 | 128 | 2006 |
Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells JG Orr, V Leel, GA Cameron, CJ Marek, EL Haughton, LJ Elrick, JE Trim, ... Hepatology 40 (1), 232-242, 2004 | 97 | 2004 |
Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation A Wilhelm, EL Shepherd, A Amatucci, M Munir, G Reynolds, E Humphreys, ... The Journal of pathology 239 (1), 109-121, 2016 | 67 | 2016 |
The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure A Chauhan, L Sheriff, MT Hussain, GJ Webb, DA Patten, EL Shepherd, ... Nature communications 11 (1), 1939, 2020 | 62 | 2020 |
Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis EL Shepherd, R Saborano, E Northall, K Matsuda, H Ogino, H Yashiro, ... JHEP Reports 3 (2), 100217, 2021 | 42 | 2021 |
CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma JCR Wadkin, DA Patten, SK Kamarajah, EL Shepherd, V Novitskaya, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (2 …, 2017 | 40 | 2017 |
The reactive oxygen species–mitophagy signaling pathway regulates liver endothelial cell survival during ischemia/reperfusion injury RH Bhogal, CJ Weston, S Velduis, H GD Leuvenink, GM Reynolds, ... Liver Transplantation 24 (10), 1437-1452, 2018 | 36 | 2018 |
Evaluation of serum and tissue levels of VAP-1 in colorectal cancer ST Ward, CJ Weston, EL Shepherd, R Hejmadi, T Ismail, DH Adams BMC cancer 16, 1-8, 2016 | 29 | 2016 |
SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress DA Patten, SK Kamarajah, JM Rose, J Tickle, EL Shepherd, DH Adams, ... Scientific reports 7 (1), 17600, 2017 | 27 | 2017 |
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies NJ Coltman, BA Coke, K Chatzi, EL Shepherd, PF Lalor, ... Toxicology letters 345, 34-45, 2021 | 13 | 2021 |
Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo EL Shepherd, S Karim, PN Newsome, PF Lalor World journal of hepatology 12 (11), 931, 2020 | 12 | 2020 |
Cellular localization and trafficking of vascular adhesion protein-1 as revealed by an N-terminal GFP fusion protein CJ Weston, EL Shepherd, DH Adams Journal of Neural Transmission 120, 951-961, 2013 | 11 | 2013 |
Novel targets in the immune microenvironment of the hepatic sinusoids for treating liver diseases DA Patten, EL Shepherd, CJ Weston, S Shetty Seminars in liver disease 39 (02), 111-123, 2019 | 9 | 2019 |
Decellularization of the human liver to generate native extracellular matrix for use in automated functional assays with stellate cells EL Shepherd, E Northall, P Papakyriacou, K Safranska, KK Sorensen, ... Hepatic Stellate Cells: Methods and Protocols, 233-244, 2023 | 3 | 2023 |
VASCULAR ADHESION PROTEIN-1 (VAP-1) IS A NOVEL BIOMARKER AND A POTENTIAL ANTI-INFLAMMATORY AND ANTI-FIBROTIC TARGET IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD): 1020 LC Claridge, N Westerlund, EL Haughton, CJ Weston, PF Lalor, DJ Smith, ... Hepatology 50, 783A-784A, 2009 | 3 | 2009 |
The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration AL Wilkinson, S Hulme, JI Kennedy, ER Mann, P Horn, EL Shepherd, ... Iscience 26 (10), 2023 | 1 | 2023 |