| Stroke genetics informs drug discovery and risk prediction across ancestries A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba, DC Posner, ... Nature 611 (7934), 115-123, 2022 | 325 | 2022 |
| Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik Nature communications 10 (1), 3300, 2019 | 276 | 2019 |
| Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome E Porcu, MC Sadler, K Lepik, C Auwerx, AR Wood, A Weihs, ... Nature communications 12 (1), 5647, 2021 | 95 | 2021 |
| C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis K Lepik, T Annilo, V Kukuškina, eQTLGen Consortium, K Kisand, Z Kutalik, ... PLoS computational biology 13 (9), e1005766, 2017 | 54 | 2017 |
| Causal inference methods to integrate omics and complex traits E Porcu, J Sjaarda, K Lepik, C Carmeli, L Darrous, J Sulc, N Mounier, ... Cold Spring Harbor perspectives in medicine 11 (5), a040493, 2021 | 16 | 2021 |
| Limited evidence for blood eQTLs in human sexual dimorphism E Porcu, A Claringbould, A Weihs, K Lepik, BIOS Consortium, ... Genome medicine 14 (1), 89, 2022 | 15* | 2022 |
| Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases MC Sadler, C Auwerx, K Lepik, E Porcu, Z Kutalik Nature Communications 13 (1), 7559, 2022 | 12 | 2022 |
| An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank G James, S Reisberg, K Lepik, N Galwey, P Avillach, L Kolberg, R Mägi, ... PLoS One 14 (4), e0215026, 2019 | 10 | 2019 |
| Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations M Lepamets, C Auwerx, M Nõukas, A Claringbould, E Porcu, M Kals, ... Human Genetics and Genomics Advances 3 (4), 2022 | 9 | 2022 |
| Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus K Männik, T Arbogast, M Lepamets, K Lepik, A Pellaz, H Ademi, ... BioRxiv, 716415, 2019 | 9 | 2019 |
| The impact of 22q11. 2 copy-number variants on human traits in the general population M Zamariolli, C Auwerx, MC Sadler, A van der Graaf, K Lepik, T Schoeler, ... The American Journal of Human Genetics 110 (2), 300-313, 2023 | 7 | 2023 |
| Consortium e, Consortium B. 2019 E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik Mendelian randomization integrating GWAS and EQTL data reveals genetic …, 0 | 6 | |
| Genetic determinants of plasma protein levels in the Estonian population A Kalnapenkis, M Jõeloo, K Lepik, V Kukuškina, M Kals, K Alasoo, ... Scientific Reports 14 (1), 7694, 2024 | 2 | 2024 |
| Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome E Porcu, MC Sadler, K Lepik, C Auwerx, AR Wood, A Weihs, DM Ribeiro, ... EUROPEAN JOURNAL OF HUMAN GENETICS 30 (SUPPL 1), 65-65, 2022 | 1 | 2022 |
| pyTWMR: transcriptome-wide Mendelian randomization in python S Oreshkov, K Lepik, F Santoni Bioinformatics 40 (8), btae505, 2024 | | 2024 |
| Widespread natural selection on metabolite levels in humans Y Timasheva, K Lepik, O Liska, B Papp, Z Kutalik Genome Research 34 (8), 1121-1129, 2024 | | 2024 |
| Response to Bassett et al. M Zamariolli, C Auwerx, MC Sadler, A van der Graaf, K Lepik, T Schoeler, ... The American Journal of Human Genetics 110 (7), 1219-1220, 2023 | | 2023 |
| Tabea Schoeler, 2, 7 Mariana Moysés-Oliveira, 6 Anelisa G. Dantas, Maria Isabel Melaragno, and Zoltán Kutalik 2, 3, 4 M Zamariolli, C Auwerx, MC Sadler, A van der Graaf, K Lepik The American Journal of Human Genetics 110, 300-313, 2023 | | 2023 |
| Metabolite levels in humans are shaped by natural selection acting on cardiometabolic fitness Y Timasheva, K Lepik, O Liska, B Papp, Z Kutalik HUMAN HEREDITY 88 (SUPPL 1), 71-71, 2023 | | 2023 |
| Reidentifying metabolic networks using observational data A van der Graaf, K Lepik, Z Kutalik HUMAN HEREDITY, 31-32, 2022 | | 2022 |
