Attenuation of miR-126 activity expands HSC in vivo without exhaustion ER Lechman, B Gentner, P van Galen, A Giustacchini, M Saini, ... Cell stem cell 11 (6), 799-811, 2012 | 235 | 2012 |
Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and Bcl2A1 as critical target genes R Piva, E Pellegrino, M Mattioli, L Agnelli, L Lombardi, F Boccalatte, ... The Journal of clinical investigation 116 (12), 3171-3182, 2006 | 193 | 2006 |
Efficient ex vivo engineering and expansion of highly purified human hematopoietic stem and progenitor cell populations for gene therapy E Zonari, G Desantis, C Petrillo, FE Boccalatte, MR Lidonnici, ... Stem cell reports 8 (4), 977-990, 2017 | 167 | 2017 |
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ... Nature genetics 52 (4), 388-400, 2020 | 162 | 2020 |
The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration C Voena, C Conte, C Ambrogio, E Boeri Erba, F Boccalatte, S Mohammed, ... Cancer research 67 (9), 4278-4286, 2007 | 128 | 2007 |
CRL4AMBRA1 is a master regulator of D-type cyclins D Simoneschi, G Rona, N Zhou, YT Jeong, S Jiang, G Milletti, AA Arbini, ... Nature 592 (7856), 789-793, 2021 | 99 | 2021 |
miRNA-126 orchestrates an oncogenic program in B cell precursor acute lymphoblastic leukemia S Nucera, A Giustacchini, F Boccalatte, A Calabria, C Fanciullo, T Plati, ... Cancer cell 29 (6), 905-921, 2016 | 73 | 2016 |
The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells B King, F Boccalatte, K Moran-Crusio, E Wolf, J Wang, C Kayembe, ... Nature immunology 17 (11), 1312-1321, 2016 | 71 | 2016 |
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis … FE Boccalatte, C Voena, C Riganti, A Bosia, L D'Amico, L Riera, M Cheng, ... Blood, The Journal of the American Society of Hematology 113 (12), 2776-2790, 2009 | 59 | 2009 |
Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening J Tan, N Shenker-Tauris, J Rodriguez-Hernaez, E Wang, ... Nature biotechnology 41 (8), 1140-1150, 2023 | 43 | 2023 |
MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia B Gentner, N Pochert, A Rouhi, F Boccalatte, T Plati, T Berg, SM Sun, ... Experimental hematology 43 (10), 858-868. e7, 2015 | 40 | 2015 |
Assessment of tocilizumab in the treatment of cancer cachexia A Berti, F Boccalatte, MG Sabbadini, L Dagna Journal of Clinical Oncology 31 (23), 2970-2970, 2013 | 36 | 2013 |
The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1 C Voena, F Di Giacomo, E Panizza, L D'amico, FE Boccalatte, ... Oncogenesis 2 (4), e43-e43, 2013 | 36 | 2013 |
Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages L Boytard, T Hadi, M Silvestro, H Qu, A Kumpfbeck, R Sleiman, KH Fils, ... Nature Communications 11 (1), 4311, 2020 | 35 | 2020 |
Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL S Rodriguez, C Abundis, F Boccalatte, P Mehrotra, MY Chiang, MA Yui, ... Leukemia 34 (5), 1241-1252, 2020 | 32 | 2020 |
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion Y Xiu, Q Dong, L Fu, A Bossler, X Tang, B Boyce, N Borcherding, ... Blood, The Journal of the American Society of Hematology 135 (2), 108-120, 2020 | 20 | 2020 |
Advances and hurdles in CAR T cell immune therapy for solid tumors F Boccalatte, R Mina, A Aroldi, S Leone, CM Suryadevara, ... Cancers 14 (20), 5108, 2022 | 11 | 2022 |
Endothelial cell–leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities LV Cappelli, D Fiore, JM Phillip, L Yoffe, F Di Giacomo, W Chiu, Y Hu, ... Blood 141 (5), 503-518, 2023 | 9 | 2023 |
Dynamic 3D chromosomal landscapes in acute leukemia A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ... bioRxiv, 724427, 2019 | 7 | 2019 |
Cell type-specific prediction of 3D chromatin architecture J Tan, J Rodriguez-Hernaez, T Sakellaropoulos, F Boccalatte, I Aifantis, ... bioRxiv, 2022.03. 05.483136, 2022 | 6 | 2022 |