Anticancer activity of stilbene‐based derivatives B De Filippis, A Ammazzalorso, M Fantacuzzi, L Giampietro, C Maccallini, ... ChemMedChem 12 (8), 558-570, 2017 | 136 | 2017 |
Lewis acid-promoted 1, 4-addition to chiral imide derivatives in the synthesis of. beta.-amino acids R Amoroso, G Cardillo, P Sabatino, C Tomasini, A Trere The Journal of Organic Chemistry 58 (21), 5615-5619, 1993 | 107 | 1993 |
N‐acylsulfonamides: Synthetic routes and biological potential in medicinal chemistry A Ammazzalorso, B De Filippis, L Giampietro, R Amoroso Chemical biology & drug design 90 (6), 1094-1105, 2017 | 76 | 2017 |
The positive regulation of eNOS signaling by PPAR agonists in cardiovascular diseases C Maccallini, A Mollica, R Amoroso American Journal of Cardiovascular Drugs 17 (4), 273-281, 2017 | 65 | 2017 |
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction A Carocci, A Catalano, F Corbo, A Duranti, R Amoroso, C Franchini, ... Tetrahedron: Asymmetry 11 (17), 3619-3634, 2000 | 58 | 2000 |
Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors M Fantacuzzi, B De Filippis, M Gallorini, A Ammazzalorso, L Giampietro, ... European journal of medicinal chemistry 185, 111815, 2020 | 57 | 2020 |
2-Substituted benzothiazoles as antiproliferative agents: novel insights on structure-activity relationships A Ammazzalorso, S Carradori, R Amoroso, IF Fernández European Journal of Medicinal Chemistry, 112762, 2020 | 47 | 2020 |
PPAR-γ agonist GL516 reduces oxidative stress and apoptosis occurrence in a rat astrocyte cell line L Giampietro, M Gallorini, B De Filippis, R Amoroso, A Cataldi, ... Neurochemistry International 126, 239-245, 2019 | 47 | 2019 |
Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells R Florio, L De Lellis, S Veschi, F Verginelli, V di Giacomo, M Gallorini, ... Scientific Reports 8 (1), 13610, 2018 | 45 | 2018 |
The benzimidazole-based anthelmintic parbendazole: a repurposed drug candidate that synergizes with gemcitabine in pancreatic cancer R Florio, S Veschi, V Di Giacomo, S Pagotto, S Carradori, F Verginelli, ... Cancers 11 (12), 2042, 2019 | 44 | 2019 |
Benzothiazole-based N-(phenylsulfonyl) amides as a novel family of PPARα antagonists A Ammazzalorso, A Giancristofaro, A D’Angelo, B De Filippis, ... Bioorganic & medicinal chemistry letters 21 (16), 4869-4872, 2011 | 44 | 2011 |
Stilbene derivatives as new perspective in antifungal medicinal chemistry B De Filippis, A Ammazzalorso, R Amoroso, L Giampietro Drug development research 80 (3), 285-293, 2019 | 42 | 2019 |
Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway A Patruno, S Franceschelli, M Pesce, C Maccallini, M Fantacuzzi, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (12), 2095-2104, 2012 | 42 | 2012 |
Targeting neuronal nitric oxide synthase as a valuable strategy for the therapy of neurological disorders C Maccallini, R Amoroso Neural regeneration research 11 (11), 1731-1734, 2016 | 38 | 2016 |
Structural development studies of PPARs ligands based on tyrosine scaffold B De Filippis, P Linciano, A Ammazzalorso, C Di Giovanni, M Fantacuzzi, ... European Journal of Medicinal Chemistry 89, 817-825, 2015 | 38 | 2015 |
Choline chloride-based DES as solvents/catalysts/chemical donors in pharmaceutical synthesis R Amoroso, F Hollmann, C Maccallini Molecules 26 (20), 6286, 2021 | 37 | 2021 |
Multitarget PPARγ agonists as innovative modulators of the metabolic syndrome A Ammazzalorso, C Maccallini, P Amoia, R Amoroso European journal of medicinal chemistry 173, 261-273, 2019 | 37 | 2019 |
Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase C Maccallini, A Patruno, N Besker, JI Alì, A Ammazzalorso, B De Filippis, ... Journal of medicinal chemistry 52 (5), 1481-1485, 2009 | 37 | 2009 |
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl) piperidine sulfonamides as aromatase inhibitors M Di Matteo, A Ammazzalorso, F Andreoli, I Caffa, B De Filippis, ... Bioorganic & Medicinal Chemistry Letters 26 (13), 3192-3194, 2016 | 36 | 2016 |
Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ JC dos Santos, A Bernardes, L Giampietro, A Ammazzalorso, ... Journal of Structural Biology 191 (3), 332-340, 2015 | 36 | 2015 |