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Hannah Leeson
Hannah Leeson
Postdoctoral Research Fellow, University of Queensland
在 uq.edu.au 的电子邮件经过验证
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Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids
J Aguado, HK Chaggar, C Gómez‐Inclán, MR Shaker, HC Leeson, ...
Aging Cell 20 (9), e13468, 2021
472021
P2X7 receptors regulate phagocytosis and proliferation in adult hippocampal and SVZ neural progenitor cells: implications for inflammation in neurogenesis
HC Leeson, MA Kasherman, T Chan-Ling, MD Lovelace, JC Brownlie, ...
Stem Cells 36 (11), 1764-1777, 2018
402018
P2X7 receptor signaling during adult hippocampal neurogenesis
HC Leeson, T Chan-Ling, MD Lovelace, JC Brownlie, BJ Gu, MW Weible
Neural Regeneration Research 14 (10), 1684-1694, 2019
292019
The hallmarks of aging in Ataxia-Telangiectasia
J Aguado, C Gómez-Inclán, HC Leeson, MF Lavin, Y Shiloh, ...
Ageing Research Reviews 79, 101653, 2022
172022
Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses
DA Ovchinnikov, SL Withey, HC Leeson, UW Lei, A Sundarrajan, ...
Human Molecular Genetics 29 (6), 990-1001, 2020
152020
Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types
MR Shaker, A Kahtan, R Prasad, JH Lee, G Pietrogrande, HC Leeson, ...
Frontiers in cell and developmental biology 10, 803061, 2022
92022
Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution
A Taherian Fard, HC Leeson, J Aguado, G Pietrogrande, D Power, ...
GeroScience 46 (1), 999-1015, 2024
42024
Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort
HC Leeson, Z Hunter, HK Chaggar, A Mackay-Sim, EJ Wolvetang
Stem Cell Research 56, 102527, 2021
32021
Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations
HC Leeson, Z Hunter, HK Chaggar, MF Lavin, A Mackay-Sim, ...
Stem Cell Research 56, 102528, 2021
32021
Real-time live-cell flow cytometry to investigate calcium influx, pore formation, and phagocytosis by P2X7 receptors in adult neural progenitor cells
HC Leeson, T Chan-Ling, MD Lovelace, JD Brownlie, MW Weible II, ...
JoVE (Journal of Visualized Experiments), e59313, 2019
32019
Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations
HC Leeson, D Goh, D Coman, EJ Wolvetang
Stem Cell Research 64, 102917, 2022
12022
Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening
ZL Hunter, HC Leeson, MR Shaker, EJ Wolvetang, L Vadlamudi
Stem Cell Research 60, 102673, 2022
12022
Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations
AT Fard, H Leeson, JA Perez, G Pietrogrande, D Power, CLG Inclan, ...
bioRxiv, 2022.01. 24.476823, 2022
12022
Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress
HC Leeson, J Aguado, C Gómez-Inclán, HK Chaggar, AT Fard, Z Hunter, ...
Neurobiology of Disease, 106562, 2024
2024
Superior Induced Pluripotent Stem Cell Generation through Phactr3-Driven Mechanomodulation of Both Early and Late Phases of Cell Reprogramming
MM Chowdhury, S Zimmerman, H Leeson, CM Nefzger, JC Mar, A Laslett, ...
Biomaterials Research 28, 0025, 2024
2024
CD146-assisted isolation and multi-omics characterisation of human pluripotent stem cell derived cranial Schwann cell precursor-like cells.
E Wolvetang, A Balachandran, K Dave, K Tiwari, C Gomez-Inclan, ...
2023
Substrate stiffness facilitates improved induced pluripotent stem cell production through modulation of both early and late phases of cell reprogramming
MM Chowdhury, S Zimmerman, H Leeson, CM Nefzger, JC Mar, A Laslett, ...
bioRxiv, 2023.02. 27.530366, 2023
2023
Thyroid hormone and ALK5 inhibitor improve maturation of human pluripotent stem cell derived hepatocytes
S Withey, D Gerrard, H Leeson, R Atkinson-Dell, S Harrison, M Baxter, ...
bioRxiv, 2022.04. 28.489845, 2022
2022
Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients
ZL Hunter, HC Leeson, MR Shaker, EJ Wolvetang, L Vadlamudi
Stem Cell Research 56, 102564, 2021
2021
Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytes
S Withey, D Gerrard, H Leeson, R Atkinson-Dell, S Harrison, M Baxter, ...
Journal of Hepatology 73 (s1), S247-S248, 2020
2020
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