The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens N Zhou, Y Jiang, TR Bergquist, AJ Lee, BZ Kacsoh, AW Crocker, ... Genome biology 20, 1-23, 2019 | 362 | 2019 |
Single-cell transcriptomics uncovers glial progenitor diversity and cell fate determinants during development and gliomagenesis Q Weng, J Wang, J Wang, D He, Z Cheng, F Zhang, R Verma, L Xu, ... Cell stem cell 24 (5), 707-723. e8, 2019 | 173 | 2019 |
Single-cell transcriptomics in medulloblastoma reveals tumor-initiating progenitors and oncogenic cascades during tumorigenesis and relapse L Zhang, X He, X Liu, F Zhang, LF Huang, AS Potter, L Xu, W Zhou, ... Cancer cell 36 (3), 302-318. e7, 2019 | 116 | 2019 |
Dual requirement of CHD8 for chromatin landscape establishment and histone methyltransferase recruitment to promote CNS myelination and repair C Zhao, C Dong, M Frah, Y Deng, C Marie, F Zhang, L Xu, Z Ma, X Dong, ... Developmental cell 45 (6), 753-768. e8, 2018 | 108 | 2018 |
Single‐cell transcriptomic analysis reveals a hepatic stellate cell–activation roadmap and myofibroblast origin during liver fibrosis in mice WU Yang, H He, T Wang, N Su, F Zhang, K Jiang, J Zhu, C Zhang, K Niu, ... Hepatology 74 (5), 2774-2790, 2021 | 95 | 2021 |
SPRINT: an SNP-free toolkit for identifying RNA editing sites F Zhang, Y Lu, S Yan, Q Xing, W Tian Bioinformatics 33 (22), 3538-3548, 2017 | 80 | 2017 |
A novel approach to remove the batch effect of single-cell data F Zhang, Y Wu, W Tian Cell discovery 5 (1), 46, 2019 | 50 | 2019 |
Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome X Dong, X Wang, F Zhang, W Tian Molecular Biology and Evolution 33 (10), 2565-2575, 2016 | 31 | 2016 |
CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair J Wang, J Wang, L Yang, C Zhao, LN Wu, L Xu, F Zhang, Q Weng, ... Nature Communications 11 (1), 4133, 2020 | 29 | 2020 |
PhenoPro: a novel toolkit for assisting in the diagnosis of Mendelian disease Z Li, F Zhang, Y Wang, Y Qiu, Y Wu, Y Lu, L Yang, WJ Qu, H Wang, ... Bioinformatics, 2019 | 29 | 2019 |
Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis Z Luo, M Xia, W Shi, C Zhao, J Wang, D Xin, X Dong, Y Xiong, F Zhang, ... Nature 612 (7941), 787-794, 2022 | 26 | 2022 |
CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling Z Zhang, F Zhang, AK Davis, M Xin, G Walz, W Tian, Y Zheng Cell reports 38 (2), 2022 | 20 | 2022 |
Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition C Fan, C Zhao, F Zhang, M Kesarwani, Z Tu, X Cai, AK Davis, L Xu, ... Proceedings of the National Academy of Sciences 118 (1), e2020102118, 2021 | 18 | 2021 |
Unsupervised inference of developmental directions for single cells using VECTOR F Zhang, X Li, W Tian Cell Reports 32 (8), 2020 | 14 | 2020 |
Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis Q Ma, L Yang, K Tolentino, G Wang, Y Zhao, UM Litzenburger, Q Shi, ... Elife 11, e79126, 2022 | 13 | 2022 |
scMAGIC: accurately annotating single cells using two rounds of reference-based classification Y Zhang, F Zhang, Z Wang, S Wu, W Tian Nucleic Acids Research 50 (8), e43-e43, 2022 | 13 | 2022 |
Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy LMN Wu, F Zhang, R Rao, M Adam, K Pollard, S Szabo, X Liu, KA Belcher, ... Science Advances 8 (44), eabo5442, 2022 | 11 | 2022 |
Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability Z Luo, D Xin, Y Liao, K Berry, S Ogurek, F Zhang, L Zhang, C Zhao, R Rao, ... Nature communications 14 (1), 762, 2023 | 10 | 2023 |
OLIG2 maintenance is not essential for diffuse intrinsic pontine glioma cell line growth but regulates tumor phenotypes Y Liao, Z Luo, Y Deng, F Zhang, R Rao, J Wang, L Xu, SS Kumar, ... Neuro-oncology 23 (7), 1183-1196, 2021 | 5 | 2021 |
Single-Cell Transcriptomics Resolves Intermediate Glial Progenitors and Uncovers a Pivotal Determinant of Cell Fate and Gliomagenesis Q Weng, J Wang, J Wang, D He, Z Cheng, F Zhang, R Verma, L Xu, ... Cell stem cell 24 (5), 707, 2019 | 4 | 2019 |