| Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity T De Bruyn, S Chatterjee, S Fattah, J Keemink, J Nicolaï, P Augustijns, ... Expert opinion on drug metabolism & toxicology 9 (5), 589-616, 2013 | 136 | 2013 |
| Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network Z Vinarov, B Abrahamsson, P Artursson, H Batchelor, P Berben, ... Advanced Drug Delivery Reviews 171, 289-331, 2021 | 119 | 2021 |
| Caco-2 cell conditions enabling studies of drug absorption from digestible lipid-based formulations J Keemink, CAS Bergström Pharmaceutical research 35, 1-11, 2018 | 79 | 2018 |
| Lipolysis-permeation setup for simultaneous study of digestion and absorption in vitro J Keemink, E Mårtensson, CAS Bergström Molecular Pharmaceutics 16 (3), 921-930, 2019 | 69 | 2019 |
| Impact of drug physicochemical properties on lipolysis-triggered drug supersaturation and precipitation from lipid-based formulations LC Alskär, J Keemink, J Johannesson, CJH Porter, CAS Bergström Molecular Pharmaceutics 15 (10), 4733-4744, 2018 | 59 | 2018 |
| Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation? LC Alskär, A Parrow, J Keemink, P Johansson, B Abrahamsson, ... Journal of Controlled Release 304, 90-100, 2019 | 42 | 2019 |
| An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems C Alvebratt, J Keemink, K Edueng, O Cheung, M Strømme, ... European Journal of Pharmaceutics and Biopharmaceutics 149, 21-29, 2020 | 27 | 2020 |
| Primary hepatocytes in sandwich culture J Keemink, M Oorts, P Annaert Protocols in In Vitro Hepatocyte Research, 175-188, 2015 | 27 | 2015 |
| Antibody-induced enhancement of factor VIIa activity through distinct allosteric pathways LM Andersen, PA Andreasen, I Svendsen, J Keemink, H Østergaard, ... Journal of Biological Chemistry 287 (12), 8994-9001, 2012 | 19 | 2012 |
| Verapamil hepatic clearance in four preclinical rat models: towards activity‐based scaling J Nicolaï, T De Bruyn, PP Van Veldhoven, J Keemink, P Augustijns, ... Biopharmaceutics & drug disposition 36 (7), 462-480, 2015 | 15 | 2015 |
| Straightforward entry to pyrido [2, 3-d] pyrimidine-2, 4 (1H, 3H)-diones and their ADME properties M Jatczak, K Muylaert, LM De Coen, J Keemink, B Wuyts, P Augustijns, ... Bioorganic & Medicinal Chemistry 22 (15), 3947-3956, 2014 | 15 | 2014 |
| Unbound ritonavir concentrations in rat and human hepatocytes J Keemink, P Augustijns, P Annaert Journal of pharmaceutical sciences 104 (7), 2378-2387, 2015 | 13 | 2015 |
| Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes M Oorts, J Keemink, N Deferm, R Adriaensen, L Richert, P Augustijns, ... Journal of pharmacological and toxicological methods 90, 31-38, 2018 | 12 | 2018 |
| Challenges in permeability assessment for oral drug product development M Koziolek, P Augustijns, C Berger, R Cristofoletti, D Dahlgren, J Keemink, ... Pharmaceutics 15 (10), 2397, 2023 | 10 | 2023 |
| Does the intake of ethanol affect oral absorption of poorly soluble drugs? J Keemink, E Sjögren, R Holm, CAS Bergström Journal of pharmaceutical sciences 108 (5), 1765-1771, 2019 | 9 | 2019 |
| Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido [3, 2-b] azepin-6-one K Muylaert, M Jatczak, B Wuyts, LM De Coen, K Van Hecke, H Loones, ... Synlett 25 (10), 1443-1447, 2014 | 9 | 2014 |
| Biopharmaceutical profiling of a pyrido [4, 3-d] pyrimidine compound library B Wuyts, J Keemink, S De Jonghe, P Annaert, P Augustijns International journal of pharmaceutics 455 (1-2), 19-30, 2013 | 9 | 2013 |
| Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay J Keemink, OJ Hedge, V Bianco, M Hubert, CAS Bergström Journal of Pharmaceutical Sciences 111 (1), 175-184, 2022 | 8 | 2022 |
| Effect of cryopreservation on enzyme and transporter activities in suspended and sandwich cultured rat hepatocytes J Keemink, N Deferm, T De Bruyn, P Augustijns, T Bouillon, P Annaert The AAPS journal 20, 1-14, 2018 | 6 | 2018 |
| In vitro disposition profiling of heterocyclic compounds J Keemink, B Wuyts, J Nicolaï, S De Jonghe, A Stella, P Herdewijn, ... International Journal of Pharmaceutics 491 (1-2), 78-90, 2015 | 4 | 2015 |
