The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton DA Canton, DW Litchfield Cellular signalling 18 (3), 267-275, 2006 | 138 | 2006 |
Phosphorylation regulates the stability of the regulatory CK2β subunit C Zhang, G Vilk, DA Canton, DW Litchfield Oncogene 21 (23), 3754-3764, 2002 | 116 | 2002 |
Phase II trial of IL-12 plasmid transfection and PD-1 blockade in immunologically quiescent melanoma AP Algazi, CG Twitty, KK Tsai, M Le, R Pierce, E Browning, R Hermiz, ... Clinical Cancer Research 26 (12), 2827-2837, 2020 | 113 | 2020 |
The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein DA Canton, MEK Olsten, K Kim, A Doherty-Kirby, G Lajoie, JA Cooper, ... Molecular and cellular biology 25 (9), 3519-3534, 2005 | 90 | 2005 |
The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane MEK Olsten, DA Canton, C Zhang, PA Walton, DW Litchfield Journal of Biological Chemistry 279 (40), 42114-42127, 2004 | 83 | 2004 |
Functional specialization of CK2 isoforms and characterization of isoform-specific binding partners DW Litchfield, DG Bosc, DA Canton, RB Saulnier, G Vilk, C Zhang Molecular and cellular biochemistry 227, 21-29, 2001 | 78 | 2001 |
Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory R Havekes, DA Canton, AJ Park, T Huang, T Nie, JP Day, LA Guercio, ... Journal of Neuroscience 32 (50), 18137-18149, 2012 | 73 | 2012 |
Assembly of protein kinase CK2: investigation of complex formation between catalytic and regulatory subunits using a zinc-finger-deficient mutant of CK2β DA CANTON, C ZHANG, DW LITCHFIELD Biochemical Journal 358 (1), 87-94, 2001 | 70 | 2001 |
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc AA Paulucci-Holthauzen, LA Vergara, LJ Bellot, D Canton, JD Scott, ... Journal of Biological Chemistry 284 (9), 5956-5967, 2009 | 65 | 2009 |
The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein DA Canton, MEK Olsten, H Niederstrasser, JA Cooper, DW Litchfield Journal of Biological Chemistry 281 (47), 36347-36359, 2006 | 58 | 2006 |
Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy A Mukhopadhyay, J Wright, S Shirley, DA Canton, C Burkart, RJ Connolly, ... Gene therapy 26 (1), 1-15, 2019 | 55 | 2019 |
Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid) DA Canton, S Shirley, J Wright, R Connolly, C Burkart, A Mukhopadhyay, ... Immunotherapy 9 (16), 1309-1321, 2017 | 50 | 2017 |
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells H Hehnly, D Canton, P Bucko, LK Langeberg, L Ogier, I Gelman, ... Elife 4, e09384, 2015 | 50 | 2015 |
Gravin is a transitory effector of polo-like kinase 1 during cell division DA Canton, CD Keene, K Swinney, LK Langeberg, V Nguyen, L Pelletier, ... Molecular Cell 48 (4), 547-559, 2012 | 44 | 2012 |
Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti–PD-1 … ML Telli, H Nagata, I Wapnir, CR Acharya, K Zablotsky, BA Fox, ... Clinical Cancer Research 27 (9), 2481-2493, 2021 | 40 | 2021 |
Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters C Burkart, A Mukhopadhyay, SA Shirley, RJ Connolly, JH Wright, ... Gene therapy, 2018 | 35 | 2018 |
ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme AE Cherry, BR Haas, AV Naydenov, S Fung, C Xu, K Swinney, ... Molecular cancer therapeutics 15 (9), 2018-2029, 2016 | 27 | 2016 |
Anchoring proteins encounter mitotic kinases DA Canton, JD Scott Cell Cycle 12 (6), 863-864, 2013 | 13 | 2013 |
Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity JY Lee, B Nguyen, A Mukhopadhyay, M Han, J Zhang, R Gujar, J Salazar, ... Molecular Therapy-Oncolytics 25, 174-188, 2022 | 9 | 2022 |
Intratumoral electroporation of plasmid encoded il12 and membrane-anchored anti-cd3 increases systemic tumor immunity M Han, B Nguyen, JY Lee, E Browning, J Zhang, A Mukhopadhyay, ... Molecular Cancer Research 20 (6), 983-995, 2022 | 9 | 2022 |