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Julio Aguado, PhD
Julio Aguado, PhD
Scientist studying mechanisms of aging
在 uq.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome
J Aguado, A Sola-Carvajal, V Cancila, G Revêchon, PF Ong, ...
Nature communications 10 (1), 4990, 2019
1052019
DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs
F Rossiello, J Aguado, S Sepe, F Iannelli, Q Nguyen, S Pitchiaya, ...
Nature communications 8 (1), 13980, 2017
1012017
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
Molecular psychiatry 28 (7), 2878-2893, 2023
832023
From “cellular” RNA to “smart” RNA: multiple roles of RNA in genome stability and beyond
F Michelini, AP Jalihal, S Francia, C Meers, ZT Neeb, F Rossiello, U Gioia, ...
Chemical reviews 118 (8), 4365-4403, 2018
832018
Telomere transcription in ageing
J Aguado, FA di Fagagna, E Wolvetang
Ageing research reviews 62, 101115, 2020
612020
Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids
J Aguado, HK Chaggar, C Gómez‐Inclán, MR Shaker, HC Leeson, ...
Aging Cell 20 (9), e13468, 2021
472021
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis
A Slonchak, X Wang, J Aguado, JDJ Sng, H Chaggar, ME Freney, K Yan, ...
Science advances 8 (48), eadd8095, 2022
252022
Klotho inhibits neuronal senescence in human brain organoids
MR Shaker, J Aguado, HK Chaggar, EJ Wolvetang
npj Aging and Mechanisms of Disease 7 (1), 18, 2021
212021
The hallmarks of aging in Ataxia-Telangiectasia
J Aguado, C Gómez-Inclán, HC Leeson, MF Lavin, Y Shiloh, ...
Ageing Research Reviews 79, 101653, 2022
172022
Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants
A Isaacs, AA Amarilla, J Aguado, N Modhiran, EA Albornoz, AA Baradar, ...
Frontiers in Immunology 13, 926262, 2022
132022
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology
J Aguado, AA Amarilla, A Taherian Fard, EA Albornoz, A Tyshkovskiy, ...
Nature aging 3 (12), 1561-1575, 2023
102023
Target-enrichment sequencing for detailed characterization of small RNAs
Q Nguyen, J Aguado, F Iannelli, AM Suzuki, F Rossiello, ...
Nature protocols 13 (4), 768-786, 2018
92018
Cellular senescence and premature aging in Down Syndrome
L Peng, AA Baradar, J Aguado, E Wolvetang
Mechanisms of Ageing and Development 212, 111824, 2023
82023
Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution
A Taherian Fard, HC Leeson, J Aguado, G Pietrogrande, D Power, ...
GeroScience 46 (1), 999-1015, 2024
42024
Noncoding RNA of Zika Virus Affects Interplay between Wnt-Signaling and Pro-Apoptotic Pathways in the Developing Brain Tissue
A Slonchak, H Chaggar, J Aguado, E Wolvetang, AA Khromykh
Viruses 15 (5), 1062, 2023
42023
Exploring aging interventions in human brain organoids
J Aguado, EJ Wolvetang
Aging (Albany NY) 14 (4), 1592, 2022
42022
Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress
HC Leeson, J Aguado, C Gómez-Inclán, HK Chaggar, AT Fard, Z Hunter, ...
Neurobiology of Disease, 106562, 2024
2024
Insights into senolytic drugs for the treatment of SARS-CoV-2 infection in the brain
J Aguado, AA Amarilla
Nature Aging, 2023
2023
Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
I Rosso, C Jones-Weinert, F Rossiello, M Cabrini, S Brambillasca, ...
Nature communications 14 (1), 7086, 2023
2023
Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence
G Pietrogrande, M Shaker, S Stednitz, F Soheilmoghaddam, J Aguado, ...
bioRxiv, 2023.08. 29.555421, 2023
2023
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